57 results about "Gamma knife" patented technology

Methods, systems and devices are presented that provide improved medical diagnostic and intervention procedures such as magnetic resonance imaging, cardiac imaging, cardiac nuclear scintigraphy, computed tomography, echocardiography, imaging to direct laser ablation, imaging to direct radio frequency radiation ablation, imaging to direct gamma knife radiation therapy, and imaging to direct radiation therapy by respiratory gating. In a preferred embodiment, one or more balloon pressure probes within a catheter are placed into the esophagus and detect pressure within the esophagus to infer respiratory air-flow. Other probes such as those based on fiber optics and other useful materials are described. Many of these devices interact poorly or not at all with magnetic and electromagnetic fields, and are particularly useful for use in respiratory gating of MRI.

A head radiotherapy device optimizing IGRT image guidance consistency is provided. A treatment bed (2) is installed obliquely at the front portion of a frame main body (11). The top surface of the treatment bed (2) is a seat-type structure. An imaging system (3) is installed in a host (1). A real-time scanning imaging device is added into a gamma knife roller component. The imaging surface of theimaging system and the isocentral focal point of a treatment beam are in a same plane. Through combining with a seat-type treatment bed structure design, the quality control of a body portion is improved. A patient can carry out IGRT image guidance and a radiation therapy state at a same location so as to avoid the reciprocating movement of the treatment bed. A mechanical error introduced during moving is eliminated, and the consistency of a real-time tumor image acquired during IGRT image guidance with an actual tumor shape and a location in the treatment state of the patient is ensured. Thetumor position is detected in real time so that the human body tumor position is always at a focal point position. Treatment precision is monitored in real time during a treatment process.

The invention discloses a gamma knife radiotherapy reverse design planning method. First, three-dimensional models of a target zone and endangered organ interest zones are reestablished; an optimization model is established; optimization parameters and genetic algorithm parameters are determined; and a graphics processing unit (GPU) is used for parallel computing for accelerating during the whole process, then solving is carried out according to an improved genetic algorithm, the process comprises initialization group gene coding, reproduction individual selecting by individual fitness calculating and accessing, individual reproduction variation group regeneration and weight adjusting, and finally a feasible treatment plan is obtained. The method has the advantages that the optimization model has good adaptability, the method can be suitable for different diseases by adjusting the weight in an objective function, according to the feature of gamma knife treatment plan designing, gene coding of the genetic algorithm, group initialization, reproduction and variation rules are improved, and according to the optimization model, a flexible effective individual fitness evaluation function is provided.

The invention discloses an implementation method and system for a 4D gamma knife plan based on breathe monitoring. A 4D gamma knife treatment plan subsystem is used for generating a 4D gamma knife treatment plan of a corresponding patient, and the 4D gamma knife treatment plan is sent to a treatment control subsystem; a breathe monitoring subsystem is used for collecting and storing patient breathe signals; a breathe predicating subsystem is used for setting up a breathe predicating reference signal parameter library of the patient and predicating the breathe time phase of the next moment in the practical treatment process of the current patient, the treatment control subsystem and the 4D gamma knife treatment plan are combined, and a radiotherapy subsystem is controlled to call corresponding gamma knife projecting range parameters to conduct actions; the radiotherapy subsystem is used for calling the corresponding gamma knife projecting range parameters to conduct radiotherapy and record treatment data in real time according to control commands of the treatment control subsystem. According to the implementation method and system for the 4D gamma knife plan based on breathe monitoring, the design of the 4D gamma knife plane can be efficiently achieved, the patient does not need to hold the breath in the treatment process, and the application range is wide.

The present invention is a method and system for developing a dynamic scheme for Gamma Knife radiosurgery based on the concept of “dose-painting” to take advantage of robotic patient positioning systems on the Gamma Knife C and Perfexion units. The spherical high dose volume created by the Gamma Knife unit will be viewed as a 3D spherical “paintbrush”, and treatment planning is reduced to finding the best route of this “paintbrush” to “paint” a 3D tumor volume. Under the dose-painting concept, Gamma Knife radiosurgery becomes dynamic, where the patient is moving continuously under the robotic positioning system.

Methods and devices are disclosed for treating a patient with an unruptured saccular aneurysm that is not associated with an arteriovenous malformation, wherein ionizing radiation is delivered to the brain of a patient through stereotactic radiosurgery. The radiosurgery may be performed with a Gamma Knife, LINAC device such as CyberKnife, or particle-beam device. The treatment impedes a natural progression of the aneurysm towards rupture and may actually obliterate the aneurysm. The treatment plan may be based in part on measured geometric properties of the aneurysm or on physical aneurysm properties such as permeability, wall thickness, wall motion, the presence of macrophages, shear stress, and flow velocities. The methods may be used in conjunction with endovascular coil embolization.

The invention relates to a gamma knife collimator. The gamma knife collimator mainly comprises a frame and a number of aperture blades which are stacked in the frame. The inner sides of a number of aperture blades form a center through hole with variable diameter together. The frame comprises a fixed base plate, a fixed cover plate and a number of connection rods which are used for fixedly connecting the fixed base plate and the fixed cover plate, wherein the fixed base plate and the fixed cover plate are arranged in parallel. The fixed base plate and the fixed cover plate are provided with through holes, wherein a ray runs through the through holes. The aperture blades are fixed between the fixed base plate and the fixed cover plate. Each aperture blade is provided with a rotary shaft fixed near the outer circumference of the fixed base plate, and a transmission shaft which is slidably connected with a driving plate. The rotatably movably connected driving plate and a number of chutes which slidably match the transmission shafts are arranged on the outer side of the fixed cover plate. The driving plate positively and reversely rotates. The chutes match the transmission shafts to form synchronous rotation of a number of aperture blades to adjust the size of the center through hole composed of a number of aperture blades. The intensity and size of the gamma ray are controlled. The gamma knife collimator has the advantages of high control accuracy and easy operation, is provided with a shielding tungsten alloy trap, and solves the problem of complex and inaccurate operation of a professional gamma knife surgery.

The invention discloses an insulating and adiabatic gamma knife stereotactic positioning frame head nail. The head nail comprises a titanium tail, an insulating and adiabatic body, and a titanium tip. The insulating and adiabatic body is of a cross structure composed of a disk and a central axis. The insulating and adiabatic body is clamped onto the lower end of the titanium tail and the top end of the titanium tip. The central axis of the insulating and adiabatic body extends into the titanium tail and the titanium tip. The head nail has the characteristics of simple structure, low cost, and good heat insulation effect. An interference fit structure is adopted. The product precision is high. A magnetic wire ring does not form eddy current during treatment. Heat or high temperature is not easy to produce. The problem of heat transfer is solved. The precision of products is improved. Effective guarantee is provided for measurement. Thus, the effect of radiotherapy is improved.

The invention discloses an automatic source converter for a gamma knife and a method thereof. The automatic source converter comprises a radioactive source protection plug shifter and a six-degree-of-freedom mechanical hand (15), wherein the protection plug shifter comprises a supporting plate (3) for supporting a radioactive source protection plug, an X-shaft guide rail (7) and a Y-shaft guide rail (4) which are communicated with each other and form a T-shaped guide rail as well as a traction mechanism (1) used for pressing closely, positioning and firmly being connected with the protection plug and then pulling the protection plug out of a mainframe of the gamma knife through the T-shaped guide rail; and the six-degree-of-freedom mechanical hand (15) is used for taking out and replacing radioactive sources. According to the invention, during shifting, the protection plug can be kept being positioned precisely so as to facilitate reinstallation, the source conversion operation is performed automatically, manual intervention can be performed at will, and the problem of radiation injury caused by manual source conversion is solved.

The invention discloses a high-precision combined type gamma knife collimator and a machining method thereof. The high-precision combined type gamma knife collimator comprises an upper positioning ring, a middle ring and a lower positioning ring. The middle ring is composed of multiple segmentation bodies. The multiple segmentation bodies are annularly combined and assembled to the annular middle ring. Each segmentation body of middle ring is provided with multiple collimator holes. The multiple collimator holes are annularly arranged in the middle ring. The upper positioning ring is installed on an upper opening of the middle ring. The lower positioning ring is installed on a lower opening of the middle ring. The middle ring is subjected to three-dimensional segmentation to form segmentation bodies, materials are selected according to the sizes of the segmentation bodies, the surface is roughly machined after heat treatment, fine machining is carried out after flaw detection, a base and the collimator holes are machined, and orderly assembly is carried out; surface rust-proof treatment is carried out after it is detected that the collimator is qualified, and the collimator is put in storage. By the adoption of the scheme of the segmentation bodies, the machining difficulty of the collimator body is lowered, the precision of the collimator parts and the collimator holes is greatly improved, the detection error of the product is reduced, and it is ensured that the requirement for focusing degree is met.

The invention provides a safe changing system of a gamma knife radiation treatment equipment radioactive source. A source changing tool (26) is changed and arranged above an effective protected transporting source lead tank (10) with an eliminated source tank lead plug (22) and an upper lead taking plug tool (29). A cobalt source box (20) is lifted from the transporting source lead tank (10) intothe source changing tool (26) for combining with a shielding member (32). The source changing tool (26) which comprises the cobalt source box (20) is conveyed to a position which corresponds with gamma knife equipment (11). Auxiliary tools such as bracket, tool cover, lead taking plug tool and the main pull rod realize convenient maintenance and repeated use. Dimension and self weight of the source changing tool are reduced. A multi-combined quick protecting structure in which the source changing tool and the lead taking plug tool are combined is designed. The safe changing system of a gamma knife radiation treatment equipment radioactive source has advantages of reducing workload of field personnel, reducing cost, improving safety in mounting and changing of the radioactive source, effectively improving in-position precision of treatment control and a treatment bed, and improving quality control of a body gamma knife.

The systemic gamma knife radio therapeutic apparatus includes one frame; one radioactive source device supported on the frame; one drive device for driving the radioactive source device; one therapeutic bed connected to the frame; one locating bed fitted to the therapeutic bed and one repeated locating device for accurate locating during multiple treatment. It features the focus converting device for driving the radioactive source device to rotate by 0-90 deg for switching the focus between two focus positions; and one helmet device for fixing the head under treatment. The present invention can complete the therapy on the trunk and the therapy on the head.

The invention discloses a whole body gamma knife alignment body, which comprises a head alignment body (7) and a body alignment body (4). The outer diameter of the head alignment body is same as that of the body alignment body; the inner diameter of the head alignment body (7) is 210 to 250mm, and the inner diameter of the body alignment body (4) is 310 to 350mm; the intrados of the head alignment body and the body alignment body are opposite and the center lines of the head alignment body and the body alignment body are overlapped; a target A of the head alignment body is overlapped with a target A' of the body alignment body, namely the ball centers (6) of the head alignment body and the body alignment body are overlapped; the ball centers are overlapped with a rotary center line (10) of a frame; and a head alignment body fixing frame (11) and a body alignment body fixing frame (9) are parallel to the rotary center line (10) of the frame. The whole body gamma knife alignment body has the characteristics of simple structure, small occupied space, wide treatment range, high accuracy, safety and reliability, and convenient maintenance, and can accurately meet the requirements on target size and dosage during treatment of the head and body.

The invention relates to the technical field of radiotherapy target area automatic sketching, and particularly relates to a radiotherapy target area automatic sketching system and method based on deeplearning which are used for solving the problems of high qualification requirements on doctors, time consumption and labor consumption in the radiotherapy target area automatic sketching process. Thesystem comprises a management client, a logic server, a forwarding server and a model server, wherein the management client is used for statistics, query and check of DCM data and management of system users and permissions; the logic server is used for defining interaction logic of main data of the front end; the forwarding server is used for providing a DCM data forwarding service between the sketching system and a gamma knife planning system or a local PACS system; and the model server is used for providing model algorithm service for medical data diagnosis, and the model server can generate an RTSS file containing a sketching result for the case data. According to the invention, the qualification requirements of physicians for learning cost and deployment cost are reduced, and time andlabor are saved.

The present invention is a method and system for developing a dynamic scheme for Gamma Knife radiosurgery based on the concept of “dose-painting” to take advantage of robotic patient positioning systems on the Gamma Knife C and Perfexion units. The spherical high dose volume created by the Gamma Knife unit will be viewed as a 3D spherical “paintbrush”, and treatment planning is reduced to finding the best route of this “paintbrush” to “paint” a 3D tumor volume. Under the dose-painting concept, Gamma Knife radiosurgery becomes dynamic, where the patient is moving continuously under the robotic positioning system.

The invention relates to a machine tool special for machining gamma-knife spherical cap focusing holes. The machine tool comprises a base, a protruding plate is arranged in the center of the base, a forming drum is installed on the outer wall of the protruding plate in a matched mode, a height control clamping groove is formed in the inner wall of the forming drum, a pressing plate is arranged on the height control clamping groove, a stand column is fixedly installed in the center of the pressing plate, and multiple balancing weights which are different in diameter are installed on the stand column in a sleeving mode. The invention aims at solving the technical problem of providing a test die which is directly formed by mixed concrete and simulates corresponding forming pressure, the test requirements can be met, and meanwhile the manufacturing cost is reduced.

The invention provides traditional Chinese medicine composition for treating gliomas. The traditional Chinese medicine composition comprises more than twenty Chinese herbal medicines including rhizoma amorphophalli, scorpions, leeches and the like. The traditional Chinese medicine composition performs phagocytosis and elimination functions on gliomas, improves microcirculation of the brain, enhances blood and oxygen metabolism, softens and reduces focuses, is suitable for patients who do not have an operation or have part of the gliomas cut off in an operation, patients suffering from gliomas again after an operation and patients who are subjected to X-knife or gamma-knife radiotherapy and chemotherapy, and especially has a more remarkable curative effect on symptoms such as headaches, nausea and vomiting, tinnitus, numbness of limbs, hyperspasmia, mental disorder, blurred or double vision and the like caused by gliomas.

A Gamma Knife heat treatment apparatus and a Gamma Knife treatment system. The Gamma Knife heat treatment apparatus comprises a radiation source (220) and a source carrier body (230). The radiation source (220) is arranged on the source carrier body (230) and is used for emitting multiple beams of gamma rays capable of focusing geometrically and forming a focus point (210). The Gamma Knife heat treatment apparatus also comprises a CBCT imaging module (310). The CBCT imaging module (310) comprises a CBCT ball pipe (240) and a dynamic planar detector (250). The ball pipe (240) is mounted onto the source carrier body (230). The dynamic planar detector (250) is mounted onto the source carrier body (230) and arranged on a side opposite to the CBCT ball pipe (240). A vertical line of connection between the CBCT ball pipe (240) and the dynamic planar detector (250) either passes through the focus point (210), or is positioned at a set distance away from the focus point (210). The Gamma Knife head treatment apparatus and the Gamma Knife treatment system allow for implantation of high precision positioning of a head tumor by means of the CBCT imaging module (310), and for fractionated treatment of the head tumor at small doses, thus protecting as much as possible normal tissues of a patient.

Photon-based radiosurgery is widely used for treating local and regional tumors. The key to improving the quality of radiosurgery is to increase the dose falloff rate from high dose regions inside the tumor to low dose regions of nearby healthy tissues and structures. Dynamic photon painting (DPP) further increases dose falloff rate by treating a target by moving a beam source along a dynamic trajectory, where the speed, direction and even dose rate of the beam source change constantly during irradiation. DPP creates dose gradient that rivals proton Bragg Peak and outperforms Gamma Knife® radiosurgery.

The invention discloses a reductant power supply device of a gamma knife treatment bed collimator drive shaft, comprising a collimator driver mechanism, wherein the collimator driver mechanism is provided with a drive motor which is connected with two independent power supplies respectively via a driver; the driver is connected with a gamma knife treatment bed control bus; any power supply is connected with a power supply state detection circuit connected with the gamma knife treatment bed control bus; and the control bus is connected with an alarm device. The invention adopts a reductant power supply consisting of two power supplies to supply power for a collimator drive shaft, and the other power supply can continue to supply power for the collimator driver mechanism when any one power supply is in failure. The power supply state detection circuit can detect the states of two power supplies in real time, and when any one power supply is in failure, the control bus alarms. The invention can effectively prevent power failure of the collimator drive shaft in the treatment process, and avoid getting out of control of the gamma rays.

The invention provides an auxiliary tool for machining a B type gamma knife treatment head part. The auxiliary tool comprises a roller and a rotating disc; the axis of the roller is perpendicular to the axis of the rotating disc; a rotating disc bearing is arranged between the roller and the rotating disc; the rotating disc is provided with a machining hole for machining the B type gamma knife treatment head part; a mounting hole for clamping the B type gamma knife treatment head part is formed in the bottom of the machining hole; the axis of the mounting hole is vertically intersected with the center line of the roller; and the rotating disc bearing on the center line of the mounting hole is provided with a fixed block for preventing rotation of an inner ring and an outer ring of the rotating disc bearing. In addition, the invention further provides a method for machining the B type gamma knife treatment head part by the auxiliary tool. The auxiliary tool satisfies the assembly requirements during and after machining; and the final precision of assembling the B type gamma knife treatment head part reaches within S phi 0.3-0.2 mm.

The invention provides a radiation treatment system based on a four-dimensional single-source gamma knife. The system includes a radiation treatment planning system, an intelligent tracking system, athree-dimensional numerical control treatment bed, a robot system, a radiation source auxiliary treatment system, an integrated control system, a three-dimensional double-digital X-ray perspective system, the three-dimensional numerical control treatment bed, the robot system, the intelligent tracking system, the three-dimensional double-digital X-ray perspective system, the radiation source and the auxiliary treatment system are all connected with the integrated control system and the radiation treatment planning system; and the radiation treatment system is used for performing instant focustracking on the 360-degree focusing projection by virtue of a collimation intensity modulated gamma ray beam which is emitted by the radiation source at the arm end of the robot system, so that the focal point obtains several times of the radiation dose of the tissues and organs around the focal point, and the dose outside the focal boundary is reduced by a cliff type, the focal tissue cells generate a radiation biological effect to occur necrosis, and a radiation treatment effect similar to surgical resection is generated.

The inventive alignment frame simplifies the task of attaching a fixation frame to a patient's skull prior to radiotherapy treatments. The frame is adjustably attachable to the fixation frame and is equipped with a bite plate that allows a patient to bite down on the bite plate to immobile the alignment-calibration frame and the attached fixation frame. The positional relationships are adjusted to bring the fixation screws into optimal locations on the patient's skull. Needle calibration assemblies placed into the fixation screw holders include clear needle guides through which a hypodermic needle is inserted to inject anesthetic into the future fixation screw location. The needle calibration assemblies are removed and the optimal length fixation screw is tightened into the anesthetized location. After all the fixation screws are in place, the patient releases the bite plate and the entire alignment-calibration frame is removed from the fixation frame.

The invention provides an intelligent projection system based on a four-dimensional single-source gamma knife. The system comprises a radiotherapy treatment planning system, an intelligent tracking system, an automatic collaborative treatment bed, a robot system, a radiation source, a human-computer interaction system and an integrated control system, the automatic collaborative treatment bed, therobot system, the intelligent tracking system, the radiation source and the human-computer interaction system are all connected with the integrated control system; the robot system is used for carrying out focus tracking and focusing irradiation on a patient bound on the automatic collaborative treatment bed, and the ray therapy beam emitted by a gamma source rod is subjected to non-isocentric intensity modulated and digital instant focus tracking laser focused four-dimensional radiotherapy plan projection through a gamma source rod and a collimator system, so that the focal point obtains several times of the radiation dose of the tissues and organs around the focal point, and the dose outside the target is reduced by a cliff type, the absorption dose of the focal tissues is accurate, thedose distribution is uniform, the focal tissue cells generate a radiation biological effect to occur necrosis, and a radiation treatment effect similar to surgical resection is generated.

The present application relates to a stereotaxic radiation fixation device, which is installed on a Gamma Knife frame and is used to fix animals or petri dishes. The two connecting parts can be fixedly connected with the Gamma Knife frame; the fixing device, the fixing device is provided with multiple, and the plurality of the fixing devices are distributed on the fixing platform, and the plurality of the fixing devices A clamping mechanism is provided at one end close to each other, and the clamping mechanism encloses a clamping space, and the animal or culture dish can be placed in the clamping space to be fixed by a plurality of the clamping mechanisms.

The invention discloses a radioactive source component for a gamma knife and belongs to the technical field of medical equipment. The radioactive source component comprises a source box and a radioactive source, wherein the source box comprises a body, wherein a plurality of source holes for radioactive source placement are formed in the body; and the source holes include a center source hole andperipheral source holes, the center source hole is superposed with the center axis of the body, and the peripheral source holes are distributed around the center source hole and are tilted to the center axis of the body, so that a gamma ray emitted from the radioactive source can be focused to irradiate a target. The radioactive source component has the beneficial effects that the radioactive source is integrated on the source box, so that the shielding difficulty of a whole machine can be reduced, radiation leakage of the radioactive source can be avoided, and the safety is improved; an emergent beam of the radioactive source has large dosage, the focusing accuracy of the target is high, the penumbra of a target region is reduced, and the radiotherapy effect of a gamma knife is optimized.The radioactive source component is simple and smart in structure and convenient for transferring, assembling and disassembling; and furthermore, the radioactive source can be protected appropriately, the safety is high, and the radioactive source can be assembled and disassembled from the component conveniently.

The invention discloses an automatic source converter for a gamma knife and a method thereof. The automatic source converter comprises a radioactive source protection plug shifter and a six-degree-of-freedom mechanical hand (15), wherein the protection plug shifter comprises a supporting plate (3) for supporting a radioactive source protection plug, an X-shaft guide rail (7) and a Y-shaft guide rail (4) which are communicated with each other and form a T-shaped guide rail as well as a traction mechanism (1) used for pressing closely, positioning and firmly being connected with the protection plug and then pulling the protection plug out of a mainframe of the gamma knife through the T-shaped guide rail; and the six-degree-of-freedom mechanical hand (15) is used for taking out and replacing radioactive sources. According to the invention, during shifting, the protection plug can be kept being positioned precisely so as to facilitate reinstallation, the source conversion operation is performed automatically, manual intervention can be performed at will, and the problem of radiation injury caused by manual source conversion is solved.

The present invention provides a real-time tracking location system. It is characterized by that based on electromagnetic induction principle and graphic image processing technique said invention combines them with focus of human body so as to make dynamic assignment and real-time tracking of human body internal organs and focus, and in the insertion therapy and medical accelerator, cobalt 60 machine and external irradiation of gamma-knife it can implement real-time tracking operation of focus.