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Water aqua medicine compounds, preparing method and applications thereof

A composition and medicine technology, applied in the field of biological preparations and their preparation, can solve problems such as inability to achieve curative effects, and achieve the effects of simple and convenient medication route, improvement of quality of life, and enhancement of phagocytosis function

Inactive Publication Date: 2010-12-22
匡建民
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the limitations of monotherapy, higher curative effect cannot be achieved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Prescription: Radix Radix 20, Honeysuckle 20g, Scutellaria baicalensis 20, Wild Chrysanthemum 20, Distilled water 500ml, Chicken embryo urine 400ml;

[0027]Weigh Radix Isatidis, Honeysuckle, Scutellaria baicalensis, and wild chrysanthemum according to the components, add 2000ml of water to decoct for 2 hours and filter for later use, add 2000ml of water to the dregs and decoct for 1.5 hours in the same way, filter and combine with the first decoction to concentrate to 500ml. Add 3 times the amount of anhydrous ethanol to precipitate for 72 hours, take the supernatant to recover ethanol, add distilled water to dilute the precipitate to 1000ml, filter to obtain a clarified liquid, and sterilize it for later use; take chicken embryos incubated for 9 to 10 days aseptically Extract the urine in the allantoic cavity and put it in a sterile bottle for later use; mix the chicken embryo urine with the above-mentioned traditional Chinese medicine extract according to the volume r...

Embodiment 2

[0029] Study on the Pharmacological Action of "Bodek"——Animal Experiments

[0030] 1 Experimental research on anticancer activity (antitumor activity in animals):

[0031] 1.1 Drugs and materials: "Bodek nasal drops", tincture of iodine, alcohol, 2ml sterile empty needle. heparin. 0.2% trypan blue saline solution. Cyclophosphamide (a product of Jiangsu Hengrui Pharmaceutical Co., Ltd., batch number 05122521). 2.5% glutaraldehyde solution.

[0032] 1.2 Experimental equipment: torque balance

[0033] 1.3 Experimental tumor strain: Sarcoma S 180 Breeding mice were cited from Institute of Materia Medica, Shandong Academy of Medical Sciences.

[0034] 1.4 Experimental animals: Healthy Kunming white mice were purchased from the Experimental Animal Center of Shandong Epidemic Prevention Station, male and female, 5-6 weeks old, weighing 18-22g.

[0035] 1.5 Preparation and inoculation of mouse sarcoma and ascites tumor models

[0036] Select intraperitoneal inoculation of sarc...

Embodiment 3

[0078] Research on anticancer activity of "Bodek"——clinical experiment

[0079] 1. Case collection

[0080] 1 Inclusion criteria:

[0081] 1.1. All the cases were outpatient or inpatient cases, all of which were diagnosed with definite malignant tumors by histology or cytology. All 200 patients were randomly divided into experimental group and control group according to 1:1. The treatment group consisted of 100 cases, including 53 males and 47 females. Age ranged from 16 to 86 years, with an average age of 63.2 years. 30 cases were initially treated and 70 cases were re-treated. 8 cases of lung cancer, 25 cases of gastric cancer, 16 cases of colorectal cancer, 19 cases of esophageal cancer, 8 cases of liver cancer, 5 cases of breast cancer, 3 cases of nasopharyngeal cancer, 1 case of lip cancer, 9 cases of ovarian cancer, 3 cases of uterine cancer, pancreatic cancer 1 case, 2 cases of bladder cancer. The control group consisted of 100 cases, including 48 males and 52 fem...

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PUM

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Abstract

The invention discloses an aqueous medicine composition, which is made by the following components: isatic root of 17 to 23 gram, honeysuckle of 17 to 23 gram, scutellaria of 18 to 22 gram, wild chrysanthemum of 18 to 22 gram, distilled water of 500 to 550 milliliter, and chick embryo urine of 400 to 450 milliliter; the content of effective components of isatic root, honeysuckle, scutellaria, andwild chrysanthemum is no less than 60 percent. The agent medicine composition of the invention has the effects of inducing human body to produce endogenous interferon, enhancing phagocytosis of macrophage, regulating T, B lymphocyte, activating the specific and nonspecific immune function, and realizing the direct damage or killing of tumor cells. The medicine of the invention belongs to Chinese medicine preparation and is a combo of Chinese medicine and inactive virus; the usage of the medicine is simple and convenient with little side effect and low cost; the invention is convenient for generalization widely in clinic; the invention can also be widely applied to family sickbed and accord with the developing direction of medical health with low cost. The invention is predicted to make benefit of about 2,000,000 Yuan.

Description

technical field [0001] The invention relates to a biological preparation and its preparation method and application, in particular to a biological preparation-like aqueous pharmaceutical composition for nasal mucosa absorption, its preparation method and its application as a medicine in the biological treatment of malignant tumors. Background technique [0002] As a common and frequently-occurring disease, tumor seriously damages people's health. According to statistics, there are more than 8 million new cancer patients and more than 6 million deaths in the world every year. In my country, the morbidity and mortality of cancer are also increasing year by year. In the 20 years from the 1970s to the 1990s, the incidence of cancer in my country rose from 900,000 to 1.6 million per year, and the number of deaths rose from 700,000 to 1.3 million per year. Current cancer treatment methods mainly include the following types: surgery, radiotherapy, chemotherapy, biological immunot...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/539A61P35/00A61K35/48A61K35/57
Inventor 匡建民王静雯匡建梅王圣芳王家林徐全民韩丽郭立群赵茂林赵惠兰刘波唐基栋赵慧琴
Owner 匡建民