Biodegradable shape memory stitched wire

The technology of a suture thread and a memory polymer is applied in the application field of medical surgical suture to achieve the effects of reducing economic burden, reducing inconvenience and wide application range

Inactive Publication Date: 2008-12-31
冷劲松
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This invention can not only solve the problem that it is difficult to perform complex suturing operations in a limited space when suturing internal wounds of the body, but also can precisely control the tightness of the wound closure, and there is no need to remove the stitches after the wound heals

Method used

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  • Biodegradable shape memory stitched wire
  • Biodegradable shape memory stitched wire
  • Biodegradable shape memory stitched wire

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Experimental program
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specific Embodiment approach 1

[0018] Embodiment 1: Preparation of a biodegradable shape memory suture thread. In this embodiment, the biodegradable shape memory suture thread is a molded solidified product of a biodegradable shape memory polymer. The biodegradable shape memory polymer used is one or a mixture of the following substances: poly-L-lactide-poly(glycolide / caprolactone) multi-block copolymer, aliphatic poly Ester-coupling agent-multifunctional monomer-adjuvant radiation crosslinking product, poly-L-lactic acid, ε-caprolactone polymer of dimethacrylate and n-butyl acrylate, rac-lactide and di Star blend of glycol, multi-block copolyester synthesized from ε-caprolactone and ethylene glycol monomethyl ether and chain extender based on carbonic anhydrase group, ε-caprolactone diol Oligomers and p-dioxanone homopolymers and diisocyanate polymers. The difference is that the biodegradable shape memory sutures made of different biodegradable shape memory polymer materials have different toughness and differ...

specific Embodiment approach 2

[0019] Embodiment 2: Preparation of a biodegradable shape memory suture. The difference between this embodiment and the first embodiment lies in the molding characteristics of the biodegradable shape memory suture. The molding method is one or more of the following methods: compression molding, injection (plastic) molding, compression molding, die-casting molding, blow molding, solid-phase hydrostatic extrusion molding, die drawing molding, sol -Gel filament picking molding, sol-gel spinning molding, melt stretching molding, directional free stretching molding, shrinkage stretching molding, solid state extrusion molding. The curing process of the biodegradable shape memory suture thread depends on the curing process of the corresponding biodegradable shape memory polymer. The shape of the biodegradable shape memory suture after solidification has two types: straight line and two ends twisted into suture kinks. The shape of each line can be specifically divided into uniform line ty...

specific Embodiment approach 3

[0020] Specific embodiment three: application of biodegradable shape memory suture thread. Heat the biodegradable shape memory suture thread to soften, stretch it into an approximate linear shape under the action of external force, and then stretch it (straight-line shape is directly stretched); cooling, the suture will remain stretched; The elongated suture thread is used to sew the wound loosely; the suture thread is heated to return to the original shape until the wound is just ideally closed; after cooling, the recovery state of the suture thread is fixed, and the wound remains in the ideal closed state; as the wound heals , The biodegradable shape memory suture will dissolve at the designed time and be absorbed harmlessly by the body.

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Abstract

The invention relates to the preparation and the application of a biodegradable shape memory suture which can not only accurately control the wound closure tightness, but also solve the problem that the operational space for the wound in the body is restricted; at the same time, the cost of treatment is significantly reduced and no stitch removal is needed after the operation. Taking a biodegradable shape memory polymer as the raw material, the suture with required specification is obtained through molding and curing process. The using method of the suture mainly lies in the temperature control: before the suturing, the suture is heated to softening temperature and then stretched to suture the wound; after the suturing, the suture is heated again and restored to the initial shape, and then the suture gradually contracts and tightens until the wound is closed ideally; finally the suture is absorbed by the body gradually along with the time without any harm caused to the human body. The biodegradable shape memory suture can be widely used in human and animal surgery wound suture.

Description

Technical field [0001] The invention relates to the preparation of a biodegradable shape memory suture thread and its application in medical surgical suture. Background technique [0002] Shape memory refers to the ability of a material to remember its original shape. Assuming that the initial shape of a material is A, it is heated to soften and then mechanically deformed to B shape. After cooling, the material automatically maintains B shape. If the material automatically returns to shape A after being heated to a certain temperature, and maintains shape A after cooling, the material is a unitary memory material; if the material automatically returns to shape A after being heated, and shape B after cooling, then this material It is a two-way memory material. The above two shape memory effects are all attributed to the transformation of the internal structural phase of the material under different conditions. At present, most shape memory materials are unidirectional memory mater...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L17/10
Inventor 冷劲松刘彦菊吴雪莲王肖华
Owner 冷劲松
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