Anti-gout drop pills of pure traditional Chinese medicine

A technology of wind dripping pills and traditional Chinese medicine, applied in the field of pure traditional Chinese medicine anti-gout dripping pills, can solve the problems of low efficacy, cure gouty diseases, poor curative effect, etc., to reduce the level of uric acid, restore the ability to excrete uric acid, and cure joint swelling. Yamato Action Difficulty Effects

Inactive Publication Date: 2011-03-23
张南 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs have defects in treatment, poor curative effect and large side effects have become the bottleneck of their clinical application, and they cannot be used for a long time
There are also some Chinese patent medicine preparations commonly used in the market to treat gout. However, due to the low efficacy of the medicine, it is difficult to fundamentally cure the gout disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 1) Dripping pills

[0034] Accurately weigh 5 grams of argyle leaf volatile oil, 5 grams of total terpenes of argyle leaf, 5 grams of plantain total glycosides, and 20 grams of polyethylene glycol 2000, and place them in a heating container while stirring and heating them until the dry powder of medicine is obtained. The melt or emulsion or suspension of the matrix is ​​ready for use. Adopt the dripping pill machine (such as the TZDW-1 dripping pill machine produced by Beijing Changzheng Tianmin High-tech Co., Ltd.), and adjust the temperature control system of the dripping pill machine so that the dripping head temperature of the dripping pill machine is heated and maintained at (50 ℃ to 90 ℃), the temperature of the condensing agent is cooled and kept at (4 ℃ to -5 ℃). When the temperature of the dripper of the dripping pill machine and the condensing agent in the condensing column are stabilized at the above-required temperature state, the molten liquid or emulsion or ...

Embodiment 2

[0038] 1) Dripping pills

[0039] Accurately weigh 10 grams of argyle leaf volatile oil, 10 grams of total terpenes of argyle leaf, 10 grams of plantago plant total glycosides, and 40 grams of polyethylene glycol 4000. The preparation method is the same as in Example 1. Each drop pill in this test contains 10 mg of argyle leaf volatile oil, 10 mg of total terpenes of argyle leaf, 10 mg of total glycosides of plantago, and 40 mg of polyethylene glycol 4000.

[0040] 2) Oral liquid

[0041] Dissolve 5 droplets in 10 ml of distilled water to prepare a suspended oral solution. Each milliliter of oral liquid contains 5 mg mugwort volatile oil, 5 mg mugwort total terpenes, 5 mg plantain total glycosides and 20 mg polyethylene glycol 4000.

[0042] Comparative sample preparation:

[0043] 1) Single drug preparation Mugwort volatile oil oral liquid

[0044] Weigh 25 mg of mugwort volatile oil to dissolve and 100 mg of polyethylene glycol 2000 in 10 ml of distilled water to prepare an oral solu...

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PUM

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Abstract

The invention belongs to the technical field of drugs, in particular to a pure traditional Chinese medicine anti-gout dropping pill; the invention develops a new generation strong-efficient non-toxic drug for treating gout-the pure traditional Chinese medicine anti-gout dropping pill which is characterized by correcting complicating disease of gout rapidly by taking the search of characteristic compounds or natural effective mixed compounds for inhibiting the formation of uric acid, enhancing the dissolution and the precipitation of urate which is deposited in joints, soft tissues, soft bonesand kidney, promoting the discharge of the uric acid from renal tubule and recovering the self-excretion ability of the uric acid of the kidney as the base point. The pure traditional Chinese medicine anti-gout dropping pill is formed by mixing volatile oil of argyi wormwood leaf, total terpenes of the argyi wormwood leaf and total glucosides of plantain seed according to certain proportion and aplurality of experiments, the pure traditional Chinese medicine anti-gout dropping pill can effectively reduce the uric acid level in blood of mice with potassium oxonate-induced hyperuricemia and greatly improve and effectively cure the potassium oxonate-induced joint swelling and mobility difficulty, and the development and the use of the new drug can allow the drug to become the specific anti-gout new drug.

Description

Technical field: [0001] The invention belongs to the technical field of medicine, and particularly relates to a pure Chinese medicine anti-gout dripping pill. Background technique: [0002] There is a substance called purine in the human body. When its metabolism is disturbed, it can cause gout. Purine undergoes a series of metabolic changes, and the final product is called uric acid. Uric acid has no physiological function in the human body. Under normal circumstances, 2 / 3 of the uric acid produced in the body is excreted by the kidneys and 1 / 3 is excreted by the large intestine. Uric acid in the body is continuously produced and excreted, so it maintains a certain concentration in the blood. In the process of purine synthesis and decomposition, a variety of enzymes are involved. Due to the disorder of congenital abnormal metabolism of enzymes, the synthesis or excretion of uric acid is increased or decreased, which can cause hyperuricemia. When the blood uric acid concentrat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/68A61K9/20A61K47/42A61P19/06A61K47/10
Inventor 张南李晓
Owner 张南
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