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Composition for treating gall stone symptom

A composition and a technique for cholelithiasis, which are applied in the field of pharmaceutical compositions, can solve the problems of unsupportable patients, very different symptoms, and cannot be used as medicines, and achieve the effects of simple and feasible production method and good clinical curative effect.

Inactive Publication Date: 2009-05-20
广东万年青制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many drugs for the treatment of cholelithiasis, but the stone expulsion effect is not ideal. Ursodeoxycholic acid has only a slight stone expulsion effect, and the stone expulsion rate is about 15%. There are also chenodeoxycholic acid, choleretic Acid, Shudantong and other stone-discharging effects are even worse
[0004] As a traditional Chinese medicine for the treatment of cholelithiasis, the biggest difficulty is that "if the attack is not strong enough, the stone cannot be removed; if the attack is too strong, the patient may not be able to support it."
Moreover, people's physique and symptoms vary greatly. Clinically, the decoction prescribed by doctors for patients can change the prescription and dosage at any time due to human factors, but it cannot be used as medicine. Patients need to decoct the prescribed medicine by themselves, which is very inconvenient

Method used

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  • Composition for treating gall stone symptom
  • Composition for treating gall stone symptom
  • Composition for treating gall stone symptom

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0131] The preparation of embodiment 1 capsule

[0132] Weigh 2000g of medicinal materials Lianmoyao, 1600g of Desmodium, 1200g of Polygonum cuspidatum, 1000g of capillary, 800g of Bupleurum, 1500g of dandelion, 900g of Cyperus cyperi, 1000g of salvia miltiorrhiza, 1000g of cassia seed, and 1000g of black plum. 120L water for one time, 96L water for the second time, decoct twice, 1.5 hours each time, combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of 1.22 (55-60°C), dry the above extract, add talc The powder is crushed into a total amount of 1500g, mixed evenly, packed into capsules, and made into 3000 capsules, 500mg per capsule.

Embodiment 2

[0133] The preparation of embodiment 2 tablet

[0134] Weigh 1500g of medicinal materials Lian Qiancao, 1000g of money grass, 800g of Polygonum cuspidatum, 800g of capillary, 500g of Bupleurum, 1000g of dandelion, 500g of Cyperus cyperi, 600g of salvia miltiorrhiza, 600g of cassia seed, and 300g of ebony. 76L water for the first time, 60L water for the second time, decoct twice, 1.5 hours each time, combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of not less than 1.22 (55-60°C), and dry the above extract , crushed into fine powder, added a little talcum powder and sodium carboxymethyl starch to a total of 1120g, mixed evenly, granulated, pressed into 3200 tablets, and obtained.

Embodiment 3

[0135] The preparation of embodiment 3 granules

[0136] Weigh 1,200g of Lianzicao, 1,500g of Desmodium, 600g of Polygonum cuspidatum, 800g of capillary, 300g of Bupleurum, 800g of dandelion, 300g of Cyperus cyperi, 1,000g of salvia miltiorrhiza, 200g of cassia seed, 200g of ebony plum, crush the above ten flavors into medium pieces, add water first 69L water for the first time, 55L water for the second time, decoct twice, 1.5 hours each time, combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of not less than 1.22 (55-60°C), and dry the above extract. Grind into fine powder, add sucrose powder to 2500g, stir well, make granules, pack 10g per bag, and get ready.

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Abstract

The invention relates to a composition for treating cholelithiasis, which relates to a traditional Chinese medicine composition for treating the cholelithiasis. The composition can be a granule, a capsule, a tablet, a pill, a dripping pill, powder or an oral liquid prepared by taking Longtube Ground Ivy Herb, desmodium, giant knotweed, Herba Artemisiae Capillaris, radix bupleuri, dandelion, rhizoma cyperi, Salvia miltiorrhiza, cassia seed and dark plum as raw materials. The medicine has better clinical treatment effect on damp-heat syndrome patients of the cholelithiasis differentiated by the traditional Chinese medicine, and has efficacies of clearing heat and promoting diuresis, dredging liver and gallbladder, and relieving pain and expelling stones simultaneously. The comprehensive treatment effect of the cholelithiasis is as follows: the total obvious effective rate is 54.2 percent, and the total effective rate is 90.9 percent; the composition has no clinical adverse reaction, and no adverse effect on hearts, livers, kidneys and peripheral hemogram; and the composition has a simple and feasible production method and can be applied in industrialized production in batches.

Description

technical field [0001] The invention relates to a pharmaceutical composition using traditional Chinese medicinal materials as raw materials, in particular to a traditional Chinese medicinal composition for treating cholelithiasis. Background technique [0002] Cholelithiasis is a common disease that seriously endangers human health. It can occur in the gallbladder, intrahepatic bile duct and common bile duct. Its prevalence varies with race, genetics, geography, diet and other factors. Epidemiological studies have shown that the number of patients with cholelithiasis has increased sharply in recent years, with an increase of about 2 times every ten years. With the gradual improvement of people's living standards in our country, the dietary structure has changed, and the incidence of cholelithiasis is rising rapidly. [0003] At present, western medicine treats cholelithiasis with operation as the main method, but the effect is not satisfactory, and there are many deficienci...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P1/16
Inventor 欧先涛王长根
Owner 广东万年青制药股份有限公司
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