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Double-channel hollow fiber film type artificial lung and manufacture method thereof

A manufacturing method and fiber membrane technology, applied in the direction of suction equipment, etc., to achieve the effects of high oxygenation, reduced pressure, and long service life

Inactive Publication Date: 2009-06-10
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the shortcoming of existing single channel hollow fiber membrane type artificial lung, provide a kind of double channel hollow fiber membrane type artificial lung, similar dual channel hollow fiber membrane type artificial lung has not been seen in the world so far any literature report

Method used

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  • Double-channel hollow fiber film type artificial lung and manufacture method thereof
  • Double-channel hollow fiber film type artificial lung and manufacture method thereof
  • Double-channel hollow fiber film type artificial lung and manufacture method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. Surface coating of hollow fiber membrane

[0031] The hollow fiber two-component coating process is adopted: the silicone rubber with a vinyl molar percentage of 5% is dissolved in tetrahydrofuran, the catalyst chloroplatinic acid solution is added, and the component is uniformly mixed to form component one, and the silicone rubber in component one The mass concentration is 5%; the cholesteryl enoate liquid crystal is dissolved in tetrahydrofuran, and the hydrogen-containing silicone oil crosslinking agent is added to stir evenly to prepare component 2, and the mass concentration of the cholesteryl enoate liquid crystal in the component 2 is 5%. After the hollow fiber is soaked in the solution of component one and component two successively, after passing through the heating device, the silicone rubber can be cross-linked and cured. After repeated coating, a uniform liquid crystal / silicone rubber cross-linked film can be coated on the surface of the hollow fiber.

...

Embodiment 2

[0040] 1. Surface coating of hollow fiber membrane

[0041] The hollow fiber two-component coating process is adopted: the silicone rubber with a vinyl molar percentage of 2% is dissolved in tetrahydrofuran, the catalyst chloroplatinic acid solution is added, and the component is uniformly prepared to form component one, and the silicone rubber in component one The mass concentration is 6%; the cholesteryl enoate liquid crystal is dissolved with petroleum ether, and the hydrogen-containing silicone oil crosslinking agent is added to stir evenly to prepare component 2, and the mass concentration of the cholesteryl enoate liquid crystal in the component 2 is 6%. After the hollow fiber is soaked in the solution of component one and component two successively, after passing through the heating device, the silicone rubber can be cross-linked and cured. After repeated coating, a uniform liquid crystal / silicone rubber cross-linked film can be coated on the surface of the hollow fiber...

Embodiment 3

[0051] 1. Surface coating of hollow fiber membrane

[0052] The hollow fiber two-component coating process is adopted: the silicone rubber with a vinyl molar percentage of 10% is dissolved in tetrahydrofuran, the catalyst chloroplatinic acid solution is added, and the component is evenly mixed to prepare component one, and the silicone rubber in component one The mass concentration is 7.5%; tetrahydrofuran dissolves the cholesteryl enoate liquid crystal, and the hydrogen-containing silicone oil crosslinking agent is added to stir evenly to prepare component 2, and the mass concentration of the cholesteryl enoate liquid crystal in the component 2 is 7.5%. After the hollow fiber is soaked in the solution of component one and component two successively, after passing through the heating device, the silicone rubber can be cross-linked and cured. After repeated coating, a uniform liquid crystal / silicone rubber cross-linked film can be coated on the surface of the hollow fiber.

[...

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Abstract

The invention provides a dual-channel hollow fibre film type artificial lung and a method thereof. The artificial lung includes a case and an inner-placed hollow fibre bundle consisted of hollow fibre, the case is made of gradient earthenware pipe and inner wall of the case is coated with ionomer film; the hollow fibre outside surface is coated with liquid crystal / silicon rubber crosslinking film. The invention also provides a method for manufacturing the artificial lung which mainly includes a coating technics of the hollow fibre and gradient earthenware pipe. The invention firstly discloses that O2 and CO2 have a dual-channel type artificial lung respectively, compared with the artificial lung with single channel, oxygen gas transmitting rate is larger and pressure fall is lower, working life is more longer and better oxygenation effect can be obtained.

Description

technical field [0001] The invention relates to a hollow fiber membrane type artificial lung, in particular to an O 2 and CO 2 A double-channel hollow fiber membrane type artificial lung with its own channel for entering and exiting, and a manufacturing method thereof. Background technique [0002] The artificial lung has the ability to regulate blood O 2 and CO 2 The function of content, its main function is to achieve O through the membrane coated on the surface of the hollow fiber 2 uptake and CO 2 discharge. As an oxygenator that has been clinically applied and commercialized, the extracorporeal membrane artificial lung still has problems such as insufficient blood transmission efficiency, decreased gas exchange capacity due to blood penetration, and shortened use time. Moreover, the oxygenators that have been clinically used in China almost rely on imports for the membrane components used. [0003] Hollow fiber membrane is a hollow fiber membrane artificial lung ...

Claims

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Application Information

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IPC IPC(8): A61M1/18
Inventor 饶华新张子勇余祥正
Owner JINAN UNIVERSITY
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