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Method for producing Chinese medicine pills

A manufacturing method and a technology of traditional Chinese medicine pills, which are applied in the fields of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of affecting patients' medication compliance, difficulty in ensuring curative effect, unfavorable convenience, etc., and achieve saving of packaging materials , reduce the number of doses, moderate fluidity effect

Active Publication Date: 2009-07-22
JIANGXI HUIREN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Concentrated pills are taken in large quantities, such as the classic patent medicine - Concentrated Liuwei Dihuang Pills, which need to take 8 pills at a time, which is not conducive to the convenience of use, affects the compliance of patients with medication, and makes it difficult to guarantee the curative effect
Moreover, in production and use, although the spherical shape has good fluidity, it also has its disadvantages: (1) the volume consumption is large, that is, the equal weight occupies a larger volume than other shapes (small bulk density); (2) the fluidity is too strong Easy to cause splashing during use

Method used

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  • Method for producing Chinese medicine pills

Examples

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Effect test

Embodiment 1

[0027] Example 1 Preparation of Special-shaped Concentrated Liuwei Dihuang Pills

[0028] According to the standard prescription of Liuwei Dihuang Pills (Concentrated Pills) recorded in the Eleventh Volume of the "Ministry of Health of the People's Republic of China Drug Standards for Traditional Chinese Medicine Prescriptions", Paeonol is extracted from Moutan Cortex; Add water to decoct Alisma and Alisma twice, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate to a thick paste with a relative density of 1.35-1.40; crush the yam and the remaining dogwood into fine powder, sieve, and mix well; The above thick paste, fine powder, and paeonol are mixed evenly to make soft materials. Pill strips are prepared with a 6.5mm orifice plate, and the pills are formed with a 15mm cutting distance capsule-shaped groove. The groove is cut off, and at the same time, the two ends are smoothed by moving horizontally to form capsule-shaped special-shaped tradit...

Embodiment 2

[0029] Example 2 Preparation of special-shaped Wuji Baifeng pills (water honey pills)

[0030] According to "Chinese Pharmacopoeia" 2005 edition, a prescription preparation "Wuji Baifeng Pills" requires conventional methods to prepare (water honey pills) soft materials; pill strips are prepared with 2.5mm diameter pill strips, and are made with 3.7mm specifications (rubbing ) Pill knife making pellets, drying to obtain spherical special-shaped pellets. The pill shape is oblong, nearly cylindrical in the middle, and nearly hemispherical at both ends. Taking Wuji Baifeng pills (water honeyed pills) as 6g each time, comparing the total volume of the conventional honeyed pills and the special-shaped pills of the present invention, the volume of the special-shaped pills of the present invention is 75% of that of the conventional honeyed pills, and it is more convenient to swallow; use packaging The material is reduced compared to conventional packaging (single dose). This product...

Embodiment 3

[0031] Example 3 Preparation of Special-shaped Qiju Dihuang Pills (Concentrated Pills)

[0032] Take 26 parts of medlar, 26 parts of chrysanthemum, 104 parts of Rehmannia glutinosa, 52 parts of Cornus officinalis (made), 39 parts of Moutan bark, 52 parts of Chinese yam, 39 parts of Poria cocos, 39 parts of Alisma, the above eight flavors, Alisma and Poria are crushed into Coarse powder, decoct twice with water, the first time for 3 hours, the second time for 2 hours, combine the decoction, filter, the filtrate is concentrated into a clear paste with a relative density of 1.30-1.35 (20°C); rehmannia glutinosa sliced, add water Decoct three times, the first time for 3 hours, the second time for 2 hours, and the third time for 1 hour, combine the decoctions, filter, and concentrate the filtrate into a clear paste with a relative density of 1.30-1.35 (20°C); 45% ethanol as solvent, 34.8 parts of Cornus officinalis, 21.8 parts of Moutan cortex, and 70% ethanol as solvent of chrysan...

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Abstract

The invention discloses a method for manufacturing a traditional Chinese medicine pill, which is characterized in that a semi-finished product of the traditional Chinese medicine pill is prepared into a bar shape with certain diameter (1), and then an arc shaped cutter which is larger than the diameter (1) is used for cutting and rubbing to form a special traditional Chinese medicine pill with shapes similar to a sphere-like shape, an olive shape, a capsule shape and the like. The dosage form has the characteristics of larger drug loading and small administration quantity compared with the prior corresponding pill.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to a preparation method of traditional Chinese medicine pills. technical background [0002] Pills are an important dosage form of traditional Chinese medicine and the main dosage form used in classic Chinese patent medicines. Specifically, they can be divided into honeyed pills, water honeyed pills, watered pills, paste pills, concentrated pills, wax pills and micro pills. [0003] The appearance of traditional Chinese medicine pills is a regular spherical shape. The preparation methods include plastic method, general method and drop method, among which the plastic method has the largest output and is the main method of industrial production. The method is: prepare a plastic material (soft material), then make it into a strip with a certain diameter, then cut it into short sections equal to the diameter of the pill strip, and then roll (knead) it into a circle. Its industrial preparation ...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61K9/20A61J3/06
Inventor 耿炤丁楚良钮犇
Owner JIANGXI HUIREN PHARMA CO LTD
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