Quick multi-wavelength tissue optical parameter measuring device and trans-construction method

Abstract

The invention belongs to the field of optical parameter measurement in tissue optics research, and relates to a multi-wavelength tissue optical parameter trans-construction method based on a neural network. The method comprises: using double integrating sphere technology and a high-sensitivity photoelectric detector to collect reflected light and transmitted light on the surface of a tested sample, and using a method of relative measurement to obtain the reflectivity, diffuse transmittance and collimation transmittance of the sample; using a Monte Carlo method to establish a mapping model of a tissue optical parameter (mua, mus and g) to a measurement amount (Rd, Td and Tc); establishing a BP neural network containing two buried layers, and adopting a gradient descent weight learning function to train a BP network; and predicting the optical parameter of the measured sample through the (Rd, Td and Tc) obtained by measurement in real time, wherein an input signal of the neural network is (Rd, Td and Tc), and an output signal is (mua, mus and g). The invention provides a device adopted by the method at the same time. The method provided by the invention can quickly and accurately measure the tissue optical parameters under multi-wavelength.

Description

technical field [0001] The invention belongs to the field of optical parameter measurement in tissue optical research, in particular to a multi-wavelength isolated tissue optical parameter detection method. Background technique [0002] With the progress of society, human beings pay more and more attention to their own health, and people pay more and more attention to health-related detection methods and early diagnosis and treatment methods. Optical-related detection and diagnosis and treatment methods have the advantages of high resolution, multi-parameters, and high spatiotemporal resolution, and have the advantages of minimally invasive or even non-invasive and non-ionization in medical diagnosis. Therefore, optical correlation methods have broad application prospects in medical diagnosis and treatment. [0003] Biomedical photonics is a discipline about the application of light in the fields of biology and medicine. Since Roentgen discovered X-rays, optics has been co...

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Problems solved by technology

Compared with the inverse Monte Carlo method, its calculation speed has certain advantages, but when the albedo of the sample is small (large absorption coefficient and small scattering coefficient), the calculation error of the inverse doubling method is relatively large

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