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Prescription for treating allergy purpura and method for preparing same

A technology for allergic purpura and drugs, which is applied in the direction of medical formulas, allergic diseases, and medical preparations containing active ingredients, etc. It can solve problems such as allergic purpura that have not been found, and achieve the effect of relieving clinical symptoms and curing diseases

Active Publication Date: 2009-10-07
JILIN BENCAOTANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, no Chinese patent medicines have been found clinically for the treatment of allergic purpura

Method used

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  • Prescription for treating allergy purpura and method for preparing same
  • Prescription for treating allergy purpura and method for preparing same
  • Prescription for treating allergy purpura and method for preparing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Embodiment 1 (granule)

[0074] prescription:

[0075] Buffalo horn 500.0g Scutellaria baicalensis 250.0g Comfrey 250.0g

[0076] Moutan bark 250.0g Palm (charcoal) 333.3g Agrimony 250.0g

[0077] Scrophulariaceae 166.7g Honeysuckle 333.3g Forsythia 166.7g

[0078] Sophora flavescens 333.3g

[0079] Preparation method:

[0080] Take comfrey, Moutan cortex, agrimony, and forsythia plus 6 times the amount of 90% ethanol to reflux and extract twice, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure (below 60°C), and concentrate to relative density 1.10~1.15 (60°C) extract, set aside; decoct dregs, buffalo horn, baicalin, palm, scrophulariaceae, flavescens with 10 times the amount of water, 1.5 hours each time, filter the decoction, Combine the filtrates, concentrate under reduced pressure (below 80°C) to a relative density of 1.10-1.15 (80°C) extract, and save for later use; take honeysuckle and add 10 times the amount of wate...

Embodiment 2

[0081] Embodiment 2 (mixture)

[0082] prescription:

[0083] Buffalo horn 500.0g Scutellaria baicalensis 250.0g Comfrey 250.0g

[0084] Moutan bark 250.0g Palm (charcoal) 333.3g Agrimony 250.0g

[0085] Scrophulariaceae 166.7g Honeysuckle 333.3g Forsythia 166.7g

[0086] Sophora flavescens 333.3g

[0087] Preparation method:

[0088]Take comfrey, Moutan cortex, agrimony, and forsythia plus 6 times the amount of 90% ethanol to reflux and extract twice, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure (below 60°C), and concentrate to relative density 1.10~1.15 (60°C) extract, set aside; decoct dregs, buffalo horn, baicalin, palm, scrophulariaceae, flavescens with 10 times the amount of water, 1.5 hours each time, filter the decoction, Combine the filtrates, concentrate under reduced pressure (below 80°C) to a relative density of 1.10-1.15 (80°C) extract, and save for later use; take honeysuckle and add 10 times the amount of water...

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Abstract

The present invention discloses a prescription, a preparing method, a usage, a main pharmacodynamics research result and the poisonous character research result for treating allergy purpuric by using a pure Chinese medicinal preparation. The prescription has characterizes of including raw materials by weight as follows: buffalo horn 6-150 parts, scutellaria 3-75 parts, groomwell root 3-75 parts, bark of peony root 3-75 parts, kitool (carbon) 4-100 parts, hairy vein agrimony 3-75 parts, radix scrophulariae 2-50 parts, flower of honeysuckle 4-100 parts, capsule of weeping forsythia 2-50 parts and sophora root 4-100 parts. The prescription originates from empirical prescription, adds, reduces and cut for forming according with traditional chinese medicine theory and many years clinical empirical. The prescription is reasonable and has functions of heat-clearing and antitoxic tablet, blood-cooling and hemostatic for treating allergy purpura. The prescription has favorable antianaphylaxis and hemostasia action, and can remove purpura in a short time. The prescription has rapid effect and reliable curative effect. The preparation has reasonable preparing technique and strong operability which is suitable for industrialization producing.

Description

Background technique [0001] Henoch-Schonlein purpura (HSP), also known as hemorrhagic capillary poisoning, is a more common hemorrhagic disease caused by capillary allergy. Due to the body's autoimmune reaction to certain allergens, the formation of immune complexes depletes small blood vessels, and extensive capillary and arteriolar inflammation occurs, and even necrotizing arteriolar inflammation. The permeability and fragility of the blood vessel wall are enhanced, and perivascular infiltration and plasma blood sample exudation lead to bleeding in subcutaneous tissue, mucous membrane and internal organs. At present, there is no Chinese patent medicine for the treatment of allergic purpura clinically. Contents of the invention [0002] The purpose of the present invention is to develop a drug effectively used for treating allergic purpura, which includes the composition, preparation method, application, main pharmacodynamic research results and toxicity research results o...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61P37/08A61P7/04A61K35/32
Inventor 位鸿陈声武荣大奇宫旭国孙庆录李光子李秉钧
Owner JILIN BENCAOTANG PHARMA
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