Preparation of magnetic molecularly imprinted polymer and application in complex sample pre-processing

A magnetic molecular imprinting and complex sample technology, applied in the field of separation and analysis, can solve problems such as large consumption of organic solvents, low analysis efficiency, and time-consuming, achieving wide applicability, broad application prospects, and removal of matrix interference.
CN101550207AInactive Publication Date: 2009-10-07JILIN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
JILIN UNIV
Publication Date
2009-10-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention specifically adopts a simple method for preparing a molecularly imprinted polymer and directly applies the molecularly imprinted polymer to the extraction separation of trace substance in the complex sample pre-processing. The invention adopts a chemical coprecipitation method for preparing Fe3O4 magnetofluid. Then the surface of Fe3O4 magnetofluid is modified with oleic acid. The template molecules and functional monomers are realized with preassembling and are mixed with the cross linker and modified magnetofluid. Then the mixture is added into the polymer solvent containing dispersing agent. After the reaction is finished, magnetic field separation is executed. The polymer is dried after eluting the formwork molecules. A three-phase extraction system which is established on the base of magnetic molecularly imprinted polymer can be directly applied to the extraction separation of complex samples of food, environment and biological sample. The method of the invention has excellent selectivity and can eliminate the matrix interference in the sample. Furthermore as the polymer has excellent magnetism, the polymer can excellently realize the separation to the sample matrix after the extraction, and the polymer has broad application prospect in the complex sample pre-processing.
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Description

technical field

[0001] The invention belongs to the technical field of separation and analysis, and specifically adopts a simple method to prepare a magnetic molecularly imprinted polymer, which is directly applied to the extraction and separation of trace substances in complex sample pretreatment. Background technique

[0002] Complex systems, such as food, environmental samples, and biological samples are mostly mixtures of many different substances, and the content of the target components to be detected is often very low. Therefore, sample pretreatment is an extremely important step in the analysis of complex samples. Most of the traditional pretreatment methods require multiple operations, which not only consume a lot of organic solvents, but also take a lot of time, and the analysis efficiency is low.

[0003] Molecular imprinting technology is a technology that uses artificial methods to prepare polymers that have specific binding effects on specific molecules and the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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