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Medicament for treating climacteric syndrome and preparation method thereof

A syndrome and medicine technology, applied to medicines for the treatment of climacteric syndrome, in the field of preparation of the above-mentioned medicines, can solve problems such as treatment difficulties, impact on personal health and quality of life, etc., and achieves reduction of production costs, production equipment and technical requirements are simple, Easy to swallow effect

Inactive Publication Date: 2010-02-17
BEIJING BORAN PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because it is accompanied by other endocrine symptoms, its treatment is relatively difficult, which seriously affects personal health and quality of life

Method used

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  • Medicament for treating climacteric syndrome and preparation method thereof
  • Medicament for treating climacteric syndrome and preparation method thereof
  • Medicament for treating climacteric syndrome and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0023] Study on the crushing yield and sterilization process of powdered medicinal materials

[0024] 1.1 Investigation on the crushing yield of powdered medicinal materials

[0025] The original preparation of this product is to pulverize the powdered medicinal materials. For the convenience of control, the medicinal materials are provisionally crushed and passed through a 100-mesh sieve, and the crushing yield of the powdered medicinal materials is investigated.

[0026] Test method: Weigh 1000g of dried Chinese yam, 350g of cinnamon and 700g of Moutan cortex, a total of 2050g of medicinal materials, 2 parts each, mix them separately, crush them, pass through a 100-mesh sieve, collect the fine powders respectively, weigh them, and calculate the powder yield. The results are shown in Table 1.

[0027] Table 1 Investigation of crushing yield

[0028]

[0029] The results show that the pulverization yield of the powdered medicinal material of this product is about 96%.

...

experiment example 2

[0032] Experimental example 2: Extraction process research

[0033] 2.1 Pre-test

[0034] According to the proportion of the prescription, accurately weigh 65g of Acanthopanax ovalica, 100g of rehmannia glutinosa, 45g of aconite (manufactured), 65g of medlar, 50g of Ligustrum lucidum (manufactured), 35g of Poria, 65g of dodder (manufactured), and 65g of Cistanche (made) 35g of Alisma, add 10 times the amount of water and decoct for 2 hours, combine the decoction, filter, and calculate the liquid absorption.

[0035] Conclusion: the amount of liquid absorbed by medicinal dregs is 10 times the amount of water 5250ml- filtrate 4000ml = the amount of liquid absorbed is 1250ml, and the amount of liquid absorbed by medicinal materials is 2.4 times.

[0036] 2.2 Test

[0037] 2.2.1 Optimizing the amount of water added due to the fact that the original water extraction process has formulated more detailed and reasonable parameters for the main factors such as the extraction time and...

experiment example 3

[0060] Experimental example 3: Concentration process research

[0061] 3.1 Liquid Concentration Method

[0062] At present, most of the industrial production uses decompression equipment for concentration. This method not only has high efficiency, but also helps to retain active ingredients. Therefore, after extracting the medicinal liquid and recovering ethanol, concentration under reduced pressure is adopted. Through experiments, it is determined that the concentration condition is concentration under reduced pressure (65-70°C, -0.08MPa). The test shows that the method has high efficiency and no bumping, so this condition is determined.

[0063] 3.2 Conditions for recovering ethanol

[0064] Ethanol recovery under reduced pressure has high efficiency and is suitable for large-scale industrial production. The present invention adopts the method of recovering ethanol under reduced pressure and investigates its specific process parameters. Combined with experience and experim...

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Abstract

The invention discloses a pharmaceutical composition for treating climacteric syndrome and a preparation method thereof. The pharmaceutical composition is prepared from acanthopanax obouatus hoo, prepared rehmannia roots, cinnamon, prepared aconite, medlar, prepared ligustrum lucidum, yam, tuckahoe, prepared dodder, prepared cistanche salsa, tree peony barks and alisma orientale. The invention aims to solve the defects of the prior oral solid pharmaceutical composition for treating climacteric syndrome and provides a condensed pill which is smaller and is easy to swallow as well as is easily accepted by patients. The preparation method of the pharmaceutical composition for treating climacteric syndrome comprises the following steps: respectively crushing the yam, the cinnamon and the treepeony barks into fine powder, and mixing the fine powder for later use; adding ten times of water into other nine Chinese medicines comprising the prepared rehmannia roots and the like to carry out decoction twice, wherein the first decoction time is 2 hours, and the second decoction time is 1 hour; combining decoction liquors, and filtering; under the conditions of the temperature of 65-70 DEG Cand the pressure of -0.08MPa, depressurizing and condensing the filter liquor into clear paste with relative density of 1.08-1.12 at the temperature of 60-70 DEG C, cooling, adding the same amount ofalcohol, stirring, and standing for one night; filtering supernatant fluid, depressurizing and recovering alcohol, and condensing the supernatant fluid into clear paste with relative density of 1.20-1.25 at the temperature of 60-70 DEG C; mixing the clear paste and the fine power, depressurizing and drying, crashing the dry paste, screening by a sieve of 100 meshes, adding 10g of carboxyrnethyl starch sodium and a proper amount of starch, and mixing.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, in particular to a medicine for treating menopausal syndrome [0002] The present invention also relates to the preparation method of the above-mentioned medicine. Background technique [0003] Menopausal syndrome is a common disease that plagues menopausal women. It is caused by hypothalamus-pituitary-ovary dysfunction caused by ovarian dysfunction in the aging process of the human body. Syndrome dominated by sexual nerve dysfunction. 90% of women will have different degrees of symptoms, and accordingly cause related diseases, of which cardiovascular and cerebrovascular diseases and osteoporosis are the most common. Because it is accompanied by other endocrine symptoms, its treatment is relatively difficult, which seriously affects personal health and quality of life. Contents of the invention [0004] The object of the present invention is to provide a medicine for ...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P15/12
Inventor 彭丽丽刘学静刘志勤黄成武
Owner BEIJING BORAN PHARM CO LTD
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