Nano-herb micro-pills for removing eel poisoning and preparation method thereof

A kind of herbal plant and nanotechnology, applied in the direction of plant raw materials, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem of interfering with sulfhydryl functional enzymes and protein activities, hindering the absorption of trace elements, and toxic and side effects of heavy metals To achieve the effect of promoting the repair of liver cell structure, good resistance to liver damage, and promoting dissolution

Inactive Publication Date: 2010-02-24
TIANJIN REBATE SCI & TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned substances all have relatively high toxicity: (1). The toxic and side effects of heavy metals mainly hinder the absorption of essential trace elements in the human body, interfere with the function of sulfhydryl groups and affect the activity of enzymes and proteins, and have acute toxicity, cumulative toxicity and long-term toxic effects. Long-term consumption of foods with high heavy metal content is likely to cause damage to multiple organs of the nervous system, skeletal system and digestive system; (2). Malachite green and nitrofurans have been found to have teratogenic, mutagenic and carcinogenic effects; (3) .Quinolones have drug resistance and some potential carcinogenic properties

Method used

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  • Nano-herb micro-pills for removing eel poisoning and preparation method thereof
  • Nano-herb micro-pills for removing eel poisoning and preparation method thereof
  • Nano-herb micro-pills for removing eel poisoning and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A kind of nano-herb pellets for detoxifying eel poisoning, the active ingredients and weight of the pellets are: 30kg of terminalia leaves; 60kg of white horse bone leaves; 72kg of olive leaves; 36kg of colored maple leaves; Body-modified nano silicon dioxide 400kg; microcrystalline cellulose 240kg; chitosan 60kg.

[0031] A preparation method for removing eel poisoning nano-herb pellets, the steps of the method are:

[0032] (1). 30kg of terminal leaves, 60kg of white horse bone leaves, 72kg of olive leaves, 36kg of color wood maple leaves, and 102kg of chrysanthemum chrysanthemum leaves, which are taken according to the weight ratio, are made into nano-herb mixed with supersonic high-pressure air jet crushing equipment body, the particle size of the nano-herb mixture is less than 120nm;

[0033] (2). Use a vacuum mixer to mix 400 kg of nano-silica by weight with the nano-herb mixture at room temperature for 30 minutes, then pass through a 100-mesh sieve to obtain mix...

Embodiment 2

[0038] A kind of nano-herb pellets for removing eel poisoning. The active ingredients and weight of the pellets are: 28kg of terminalia leaves; 58kg of white horse bone leaves; 70kg of olive leaves; 34kg of colored maple leaves; Body-modified nano silicon dioxide 402kg; microcrystalline cellulose 242kg; chitosan 62kg.

[0039] The steps of the preparation method are the same as in Example 1.

Embodiment 3

[0041] A kind of nano-herb pellets for detoxifying eel poisoning, the active ingredients and weight of the pellets are: 32kg of terminalia leaves; 62kg of white horse bone leaves; 74kg of olive leaves; 38kg of colored maple leaves; Body-modified nano silicon dioxide 398kg; microcrystalline cellulose 238kg; chitosan 58kg.

[0042] The steps of the preparation method are the same as in Example 1.

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Abstract

The invention relates to nano-herb micro-pills for removing poisoning and a preparation method thereof. The micro-pills comprises the following active components in percentage by weight: 2.8 to 3.2 percent of terminalia leaf, 5.8 to 6.2 percent of serissa serissoides leaf, 7.0 to 7.4 percent of olive leaf, 3.4 to 3.8 percent of mono maple leaf, 10.0 to 10.4 percent of wild chrysanthemum leaf, 39.8to 40.2 percent of nano-silicon dioxide modified by organic ligand, 23.8 to 24.2 percent of microcrystalline cellulose and 5.8 to 6.2 percent of chitosan. The nano-herb micro-pills can effectively reduce contents of heavy metal elements and toxic substances, such as malachite green, nitrofurans, carbostyril and the like in eel bodies, contributes to the repair of eel livers, adopts pure plant components as raw materials without new residues in the eel organism, has high safety, and simultaneously meets the national requirement of environmental protection.

Description

technical field [0001] The invention relates to an antidote in aquaculture, in particular to a nanometer herbal plant pellet for detoxifying eel poisoning and a preparation method thereof. Background technique [0002] Heavy metals such as Cd, Hg, Pb, Cu, and toxic substances such as malachite green, nitrofurans, and quinolones in the aquaculture environment mainly come from drug residue pollution in agriculture, domestic sewage, chlor-alkali industry, battery manufacturing, and mining, etc. industrial pollution. The above-mentioned substances all have relatively high toxicity: (1). The toxic and side effects of heavy metals mainly hinder the absorption of essential trace elements in the human body, interfere with the function of sulfhydryl groups and affect the activity of enzymes and proteins, and have acute toxicity, cumulative toxicity and long-term toxic effects. Long-term consumption of foods with high heavy metal content is likely to cause damage to multiple organs o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61K9/16A61K47/04A61K47/38A61P1/16A61P39/02A61K33/00
Inventor 陈庆忠孙建
Owner TIANJIN REBATE SCI & TECH DEV
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