On-line detection method of near infrared spectrum for production process of traditional Chinese medicine, pill of six ingredients with rehmannia
A technology of Liuwei Dihuang Pills and near-infrared spectroscopy, which is applied in the field of quality inspection in the production process of traditional Chinese medicine, can solve the problems of cumbersome process, high labor intensity, unfavorable continuous production, etc., and achieve the effect of good reproducibility and simple detection method
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0033] An alcohol extraction process of Liuwei Dihuang Pills is detected on-line, and its specific steps are:
[0034] (1) Add 10 times the amount of 1L 95% ethanol to 100g of Moutan cortex decoction pieces, the extraction temperature is 85°C, the extraction time is 2h, extraction is performed twice, sampling is done every 10min, and 3 batches of the above samples are prepared for modeling;
[0035] (2) Determining the content of paeonol and paeoniflorin in the above-mentioned technological process sample with high performance liquid chromatography, and use this content value as a calibration set sample during modeling;
[0036] The high performance liquid chromatography condition that adopts in the above-mentioned step (2) is: mobile phase 0.5% formic acid (A)-acetonitrile (B), phase B gradient is, 0~8min 90~85%, 8~20min 85~80% , 20-25min 80-40%, 25-30min 40-15%; column temperature 25°C, flow rate 1ml / min, detection wavelength 250nm, running time 35min, injection volume 10μl;...
Embodiment 2
[0044] An extraction process of water-soluble components of Liuwei Dihuang Pills is carried out on-line detection, and the specific steps are as follows:
[0045] (1) Mix 23g of Cornus officinalis, 267g of Rehmannia glutinosa, 100g of Poria cocos, 100g of Alisma chinensis and the dregs of moutan cortex in Example 1, add 10 times the amount of water, decoct and extract for 1.5h, and take samples every 10min to prepare 3 batches of the above samples for modeling purposes;
[0046] (2) Determination of the content of loganin and gallic acid in the above-mentioned technological process sample with high performance liquid chromatography, take this content value as the calibration set sample when modeling;
[0047] The high performance liquid chromatography condition is the same as method in embodiment 1, and the high performance liquid chromatography of water extraction process terminal sample is as follows Figure 4 As shown, the extraction curves of loganin and gallic acid over ...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com