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Anti-additive medicament and preparation method thereof

A technology of drugs and medicaments, applied in the field of detoxification drugs and preparations, can solve problems such as easy conversion to another kind of dependence, good detoxification of western medicine, and large cardiovascular system response, so as to shorten the psychological demand for drug relief and shorten the time of detoxification , the effect of high technological content

Inactive Publication Date: 2010-05-12
严千燮 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Generally speaking, drugs have four common characteristics: force majeure, which compels users to use the drug continuously, and obtains it by any means; continuous use has a tendency to increase the dose; psychological dependence on the drug And physical dependence (addiction), drug addiction leads to physical fitness, immunity decline, body organs are damaged, so that drug addicts lose the ability to live and work, which will have harmful consequences for families and society
[0003] Although there are more than ten kinds of detoxification drugs in China, these withdrawal treatment drugs mainly rely on folk remedies or contain narcotic drugs instead of drugs to suppress nerve excitement and relieve withdrawal symptoms. Commonly used are methadone and clonidine, etc., which are limited to opioids However, such chemical synthetic drugs have side effects and adverse reactions such as slow detoxification, easy conversion to another kind of dependence, easy poisoning, easy addiction, large cardiovascular system reaction, and high relapse rate.
Western medicine detoxification is better, recovery is more difficult
At present, it is still difficult to find drugs that do not contain scopolamine, chlorpromazine, or have no dependence on physiological withdrawal or relieve drug craving. There is still a blank in the aspect of drug withdrawal or eliminating drug craving.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A kind of detoxification medicine, is made up of following raw material by weight percentage:

[0019] Ledum latifolia 70% Cymene 5%

[0020] Amber 5% Gallic Star 3%

[0021] Ice Sheet 5% Windproof 5%

[0022] Cinnabar 2% Whole Worm 5%

[0023] The preparation method of above-mentioned detoxification drug: comprises the following steps:

[0024] (1) Under the condition of 0.5kg pressure and 100°C, Ledum broadleaf was extracted by steam distillation for 2 hours, and the volatile oil part in the upper layer was separated with an appropriate separator, and then used; or the water layer was washed 3 times with chloroform , the ratio of water layer to chloroform was 3:1, the chloroform layers were combined, the chloroform was recovered, and the residual liquid was combined into the volatile oil fraction for use.

[0025] (2) Take cinnabar and crush it, pass it through a 120-mesh sieve to get fine powder, and set it aside; or process cinnabar: take cinnabar and use a magn...

Embodiment 2

[0029] A kind of detoxification medicine, is made up of following raw material by weight percentage:

[0030] Ledum latifolia 80% Cymene 3%

[0031] Amber 5% Gallic Star 2%

[0032] Ice flakes 2% Windproof 3%

[0033] Cinnabar 2.5% Whole Worm 2.5%

[0034] Preparation method is the same as embodiment 1

[0035] Animal experiment:

[0036] The detoxification drug of the present invention has been tested on animals according to conventional methods and has confirmed the effects of acute toxicity, long-term toxicity, anticonvulsant, analgesia, sedation and other detoxification drugs.

[0037] The results of animal experiments show that the present invention has very obvious inhibitory effect on addicted animals and has no drug dependence.

[0038] The detoxification drug of the invention has the advantages of low cost, safety, reliability, high technological content, small toxic and side effects, can obviously shorten the detoxification time and relieve the psychology of dru...

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PUM

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Abstract

The invention discloses an anti-additive medicament, which comprises the following raw materials in percentage by weight: L.palustre var. dilatatum wablbg 70-80, amber 3-5, arisaema cum bile 2-3, divaricate saposhnikovia root 3-5, borneol 2-5, cymene 3-5, cinnabar 2-3 and scorpion 2.5-5. The medicament has the advantages of remarkably relieving lacrimation, rhinorrhoea, body aches, dysphoria and other symptoms which are reactions to with withdraw of addition, increasing the immunity of human body, obviously shortening the time for addition withdraw, eliminating the psychological need for drugs, along with remarkable anti-addition effect, quick response, no obvious toxic nor side effects and no adverse reactions. The medicament can help drug addicts to get rid of dependence on drugs and is a novel, non-addictive and ideal anti-additive medicament. The invention also provides a preparation method of the anti-additive medicament.

Description

technical field [0001] The invention relates to a drug for detoxification and a preparation method thereof. technical background [0002] In recent years, with the steady development of the international economy, drugs are increasingly rampant all over the world, endangering human health and the peace of the international community, and have become a serious international public hazard, gradually attracting global attention. In view of the serious situation of the continuous development of international drug trafficking and drug abuse, as well as the continuous spread of drug abuse activities in some areas of our country, the number of drug abusers is increasing day by day, which has become a serious social problem. The World Health Organization (WHO) divides substances used as drugs into 8 categories: morphines, barbiturates, alcohols, cocaines, Indian cannabis, amphetamines, KHATs and hallucinogens. Others include nicotine, volatile solutions, etc. At present, there are ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8884A61P25/36A61K31/015A61K31/045A61K33/28A61K35/10A61K35/64A61K35/646
Inventor 严千燮
Owner 严千燮