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Wound antibiotic flushing fluid and preparation method thereof

A technology for washing liquid and wounds, which is applied in the directions of topical antibacterial agents, pharmaceutical formulations, medical preparations with inactive ingredients, etc. Low cost and cheap effect

Inactive Publication Date: 2010-06-02
ZHEJIANG KUNZHILIN BIOMEDICINE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And it does not have long-term antibacterial effect, and it does not moisturize and moisturize the skin

Method used

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  • Wound antibiotic flushing fluid and preparation method thereof

Examples

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Embodiment 1

[0032] A kind of wound antibacterial washing liquid, its raw material formula is as follows: in wound washing liquid, chlorhexidine acetate 0.5g, silver nitrate 500ug, dehydrated alcohol 10ml, glycerin 10ml, carbomer 940 0.5g, Tween 80 5g, phosphoric acid 5g, the balance of deionized water is 70ml. Configured as 100ml wound antibacterial rinse.

[0033] During preparation, dissolve carbomer 940 in water at a temperature of 70 degrees, then add chlorhexidine acetate, silver nitrate, absolute ethanol, glycerin, Tween 80, and phosphoric acid into it respectively, and stir for 30 minutes.

Embodiment 2

[0035] In the wound washing solution, chlorhexidine acetate 0.01g, silver nitrate 1000ug, absolute ethanol 70ml, glycerin 15ml, carbomer 940 1g, polyvinyl alcohol 0.5g, Tween 80 2g, phosphoric acid 2g, lactic acid 3g, deionized 10ml of water. Configured as 100ml wound antibacterial rinse

[0036] During preparation, dissolve carbomer 940 and polyvinyl alcohol in water at a temperature of 70 degrees, then add chlorhexidine acetate, silver nitrate, absolute ethanol, glycerin, Tween 80, lactic acid, and phosphoric acid into it respectively, and stir for 40 minutes .

Embodiment 3

[0038] In the wound washing solution, 1g of chlorhexidine acetate, 50ug of silver nitrate, 20ml of absolute ethanol, 10ml of glycerin, 1g of carbomer 940, 1g of sodium polyacrylate, 2g of Tween 80, 2g of triethanolamine, 3g of citric acid, 60ml of ionized water. Configured as 100ml wound antibacterial rinse

[0039] During preparation, dissolve carbomer 940 and sodium polyacrylate in water at a temperature of 30 degrees, then add chlorhexidine acetate, silver nitrate, absolute ethanol, glycerin, Tween 80, triethanolamine, and citric acid to it respectively , and stirred for 1 hour.

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Abstract

The invention discloses a wound antibiotic flushing fluid and a preparation method thereof. Counted by 100 ml of wound antibiotic flushing fluid, the the formula of the wound antibiotic flushing fluid comprises the following raw materials: 0.01-2 g of chlorhexidine salt, 3-1,000 micrograms of silver nitrate, 10-70ml of absolute ethyl alcohol, 5-20 ml of emollient, 0.5-5g of thickening agent, 0.05-5g of tween 80, 0.5-5g of pH adjusting agent and 20-90ml of deonized water, wherein the chlorhexidine salt is chlorhexidine acetate or chlorhexidine gluconate; and the emollient is glycerol. The preparation method comprises the following steps of: dissolving the thickening agent in the deonized water, then respectively adding the chlorhexidine salt, the silver nitrate, the absolute ethyl alcohol, the emollient, the tween 80 and the pH adjusting agent into the mixed solution and stirring for 30 minutes to 2 hours. The wound antibiotic flushing fluid contains various antibiotic components and considerably strong broad spectrum bacteriostasis and sterilization functions, can kill various bacterial and fungus and has constant antibacterial action.

Description

technical field [0001] The invention relates to the technical field of wound disinfection, in particular to a wound antibacterial flushing solution for reducing the microbial content in a wound and a preparation method thereof. Background technique [0002] The skin is the first barrier between the body and the outside world. It also has its own special physiological functions, which can prevent the invasion of bacteria and viruses. But when the skin is damaged, this first barrier is also broken, and the human body will be attacked by bacteria and viruses, so inflammation will occur, which will affect the patient's health, and may even threaten the patient's life, so for Antibacterial wound disinfection is very important. [0003] At present, most hospitals use ethanol or iodine to disinfect patients' wounds. But because these two kinds of materials can't thoroughly eliminate the bacteria and most of the viruses that grow on the skin, there is no obvious antibacterial effe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/38A61K9/00A61K47/32A61K47/38A61P31/02A61K31/045A61K31/19A61K31/191
Inventor 魏坤吴远曾晓峰舒丽君
Owner ZHEJIANG KUNZHILIN BIOMEDICINE TECH
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