Inactivated vaccine for streptococcus suis and pasteurella multocida diseases and preparation method thereof
A Pasteurella and Streptococcus suis technology, applied in antibacterial drugs, pharmaceutical formulations, bacterial antigen components, etc., can solve problems such as waste, ineffective drug treatment, antibiotic drug residues, etc., and achieve the effect of easy operation and cost reduction
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0031] This product is selected from pathogenic Streptococcus equi subspecies zooepidemic strain C55138 of Langeri group C, Streptococcus suis type 2 HA9801 strain, Pasteurella capsule A group and capsule B group bacteria inoculated in a suitable medium for cultivation. The culture is inactivated by formaldehyde solution to remove residual toxins, and then concentrated and prepared by adding aluminum hydroxide gel. Various bacterial infections caused by group B bacteria. This includes several of the most important bacterial diseases that are currently prevalent. The strains used in the manufacture and inspection of this product are Streptococcus equi subsp. zooepidemicus strain C55138 of Langeri C group, Pasteurella multocida P71 strain of capsular group A and Pasteurella multocida C44-1 of capsular group B group ( C44-8) strains and other virulent strains can be used for efficacy inspection, all of which are identified, kept and supplied by the China Veterinary Drug Administ...
Embodiment 2
[0067] Example 2 Efficacy Research
[0068] With 20 healthy susceptible pigs, 2ml of the vaccine prepared in Example 1 was injected intramuscularly, containing 1 dose; after 21 days, each virulent strain was used for virulent challenge.
[0069] Streptococcus group C C55138 strain:
[0070] Select 5 immunized pigs, together with 5 control pigs with the same conditions, inject the lethal dose of virulent bacteria liquid of C55138 strain, and observe for 10 days. If more than 4 / 5 of the immunized pigs are protected and more than 4 / 5 of the control pigs die, they are qualified.
[0071] Streptococcus suis type 2 HA9801 strain:
[0072] Select 5 immunized pigs, together with 5 control pigs with the same conditions, to attack with a lethal dose of HA9801 virulent strain, and observe for 10 days. More than 4 / 5 of the control group died, and more than 4 / 5 of the immunized group were protected, which was judged as qualified.
[0073] Pasteurella strain P71:
[0074] Select 5 immuni...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com