2 results about "Streptococcus sobrinus" patented technology

The application belongs to the technical field of biological medicine, and particularly relates to an antimicrobial peptide and application thereof in preparation of products for preventing and / or treating oral diseases. The amino acid sequence of the antimicrobial peptide Perceptide-302 is shown as SEQ ID NO. 1. Experimental results of the application show that the polypeptide can effectively inhibit and kill oral pathogenic bacteria at a low concentration, the minimum inhibitory concentration (MIC) of the polypeptide on six kinds of bacteria, including Streptococcus mutans, Streptococcus sobrinus, Streptococcus sanguis, Streptococcus gordonii, Lactobacillus casei and Lactobacillus acidophilus, is 2.5 μg / mL-5 μg / mL, the minimum bactericidal concentration (MBC) is 5 μg / mL-10 μg / mL, and mechanism research is carried out on the most important clinical Streptococcus mutans. The application provides a new active ingredient and technical approach for developing a new type, efficient and safe oral disease prevention and treatment drug and product.

The invention belongs to the technical field of lactobacillus paracasei, and particularly relates to a lactobacillus paracasei LPa-6 strain and application thereof in atopic dermatitis. The lactobacillus paracasei LPa-6 strain not only has the performance of targeted inhibition of Enterobacter cloacae, Streptococcus sobrinus and Aloscardovia omnicola, but also can be used for increasing the concentration of anti-inflammatory factors, regulating Th1 / Th2 imbalance, increasing the abundance of effective microbial communities in intestinal tracts, and effectively relieving and improving the symptoms of atopic dermatitis, and can be used for preventing and treating enterobacter cloacae, Streptococcus sobrinus and Aloscardovia omnicola, and preventing and treating enterobacter cloacae, Streptococcus sobrinus and Aloscardovia omnicola.