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Melt crystallization preparation technology of DC (direct compression) grade xylitol

A fusion crystallization and preparation technology, which is applied in food preparation, food science, application, etc., can solve the problems of high cost and complicated process, and achieve the effects of reducing hygroscopicity, simplifying production process, and enhancing plasticity and compressibility

Active Publication Date: 2013-04-17
FUTASTE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to overcome the deficiencies of the prior art, the present invention provides a melting and crystallization preparation process of DC-grade xylitol to solve the problem of preparing DC-grade xylitol in the prior art. Xylitol crystals are pulverized and then mixed with some adhesives , leading to problems such as complex process and high cost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] 1. Take 800 grams of xylitol solution with a mass percentage concentration of 60%, add it to a round bottom flask with a volume of 1L, and evaporate and concentrate it to a mass percentage concentration of 98% at a temperature of 170°C to obtain a xylitol slurry 490 grams;

[0016] 2. Transfer the evaporated and concentrated xylitol slurry to a container pre-insulated at 95°C, and adjust the stirring speed to 110 rpm to lower and stabilize the temperature of the feed liquid to 95°C;

[0017] 3. Adjust the stirring speed to 300 rpm, add 20 grams of 100-mesh micropowder grade xylitol, stir for 300 minutes, transfer to a stainless steel tray for cooling and crystallization, make it completely solidified, and obtain 495 grams of block xylitol solids;

[0018] 4. Use a universal pulverizer to pulverize the massive xylitol solid, and then pass through an 80-mesh sampling sieve to obtain 370 grams of an 80-mesh DC-grade xylitol product. After tableting, the obtained tablet xy...

Embodiment 2

[0020] 1. Take 700 grams of xylitol solution with a mass percentage concentration of 65%, add it to a round bottom flask with a volume of 1L, and evaporate and concentrate it to a mass percentage concentration of 98.5% at a temperature of 150°C to obtain a xylitol slurry 462 grams;

[0021] 2. Transfer the evaporated and concentrated xylitol slurry to a pre-insulated container at 90°C, and adjust the stirring speed to 100 rpm to lower and stabilize the temperature of the feed liquid to 90°C;

[0022] 3. Adjust the stirring speed to 350 rpm, add 25 grams of γ-sorbitol crystals, stir for 200 minutes, transfer to a tray wrapped in tin foil for cooling and crystallization, and make it completely solidified to obtain 475 grams of block xylitol solids ;

[0023] 4. Use a universal pulverizer to pulverize the massive xylitol solid, and then pass through a 70-mesh sieve to obtain 325 grams of a 70-mesh DC grade xylitol product. After tableting, the obtained tablet xylitol product ha...

Embodiment 3

[0025] 1. Take 750 grams of xylitol solution with a mass percentage concentration of 70%, add it to a round bottom flask with a volume of 1L, and evaporate and concentrate it to a mass percentage concentration of 99% at a temperature of 160°C to obtain a xylitol slurry 525 grams;

[0026] 2. Transfer the evaporated and concentrated xylitol slurry to a pre-insulated container at 100°C, and adjust the stirring speed to 120 rpm to lower and stabilize the temperature of the feed liquid to 100°C;

[0027] 3. Adjust the stirring speed to 400 rpm, add 15 grams of micropowder grade xylitol and 10 grams of γ-sorbitol crystals, stir for 400 minutes, transfer to a tray wrapped in tin foil for cooling and crystallization, and make it completely solidified to obtain Block xylitol solid 550 grams;

[0028] 4. Use a universal pulverizer to pulverize the massive xylitol solid, and then pass through a 90-mesh sieve to obtain 500 grams of a 90-mesh DC-grade xylitol product. After tableting, t...

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Abstract

The invention discloses a melt crystallization preparation technology of DC (direct compression) grade xylitol, which obtains a DC grade xylitol product by adopting a melt crystallization method and the processing steps of evaporation concentration, temperature adjustment, stirring, crystallization, and sieving. Through adjusting the crystallization technology of xylitol, the invention changes the crystallization form of the oylitol by using the melt crystallization method and reduces the crystallization density of the xylitol and enables the oxylitol to be easily compressed. The prepared DC grade xylitol product has reduced hygroscopicity and enhanced flowability, plasticity and compressibility, which is beneficial to tabletting. The tablet of the DC grade xylitol product has obviously enhanced hardness, friability, disintegration time and palatability, achieves the requirements for preparing the olylitol buccal tablets, and has excellent effect.

Description

technical field [0001] The invention belongs to the technical field of functional sugar alcohol production, and in particular relates to a process for preparing DC-grade xylitol by using a melt crystallization method. Background technique [0002] Xylitol is a white crystalline powder with a sweetness similar to that of sucrose, but lower in calories than sucrose. It is not only a substitute for daily sugar for healthy people, but also a nutritional and therapeutic agent for diabetics. Because xylitol is not easy to be used by cariogenic streptococcus, it can promote the absorption of corresponding minerals by teeth, and the heat of dissolution of xylitol is negative, and when it melts in the mouth, it will produce a cool feeling due to heat absorption, Xylitol has good effects on tooth protection, oral care, prevention of otitis media, and fresh breath. In order to make xylitol stay in the oral cavity for a longer time without chewing, it is generally made into xylitol loz...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07C31/18C07C29/74A61K31/047A61K9/16A23L1/236A23L27/30
Inventor 田强邱学良王成福赵光辉
Owner FUTASTE PHARM CO LTD
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