Method for separating and purifying coptisine monomers

A technology for separation and purification of coptisine, which is applied in the field of separation and purification of coptisine monomer, can solve problems such as inability to strengthen the determination of coptisine content, no coptisine, lack of high purity, etc., achieve good separation effect, easy to scale up production, and easy The effect of product quality
CN101781307BInactive Publication Date: 2012-03-07CHENGDU PUSH BIOLOGICAL TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHENGDU PUSH BIOLOGICAL TECH
Publication Date
2012-03-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method for separating and purifying coptisine monomers, comprising the steps of extracting, concentrating, leaching, dissolving and filtering, performing preparative high performance liquid chromatography and separating, recycling products and the like. The method of the invention has simple and convenient operation, short production cycle, high separating efficiency, stable process and low cost, and can realize preparing great amount of the high-purity coptisine monomers by separation; and the obtained coptisine monomers have high purity, and can be used as comparison products in assaying.
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Description

technical field

[0001] The invention relates to the technical field of methods for isolating compound monomers from plants, in particular to a method for separating and purifying coptisine monomers. Background technique

[0002] Coptis coptidis (Rhizoma coptidis) is the dry rhizome of Coptis chinensis Franch., Coptis deltoidea C.Y.Cheng et Hsiao or Coptis teeta Wall. "Yalian", "Yunlian". Coptis chinensis is bitter and cold in nature, and it has the effects of clearing away heat and dampness, purging fire and detoxifying through the heart, spleen, stomach, liver, gallbladder and large intestine meridians. For damp heat and fullness, vomiting and acid regurgitation, diarrhea, jaundice, high fever and coma, hyperactivity of heart fire, upset and insomnia, red eyes, toothache, thirst, carbuncle and furuncle; external treatment of eczema, eczema, ear canal Pus.

[0003] Coptisine is a characteristic chemical component of Coptis chinensis, and it is also the most active proberb...

Claims

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