Phosphatidylinositol-3-kinase inhibitor and application thereof

A technology of kinase inhibitor and phosphatidylinositol, which is applied in the field of tumor treatment drugs, can solve the problems of unseen function and application reports, and achieve the effect of low toxicity
CN101849934AInactive Publication Date: 2010-10-06SUZHOU UNIV
4 Cites 11 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SUZHOU UNIV
Publication Date
2010-10-06
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses new application of a 2-(4-fluorophenyl)-3-nitro-8-O-ethyl-2-hydro-benzopyran compound, in particular application of the compound serving as phosphatidylinositol-3-kinase (PI3K) inhibitor. The PI3K inhibitor can inhibit PI3K and disturb a PI3K / AKT signal channel, has good treatment effect on multiple tumors, particularly malignant hematological diseases, can effectively control the propagation of tumor cells and induce the apoptosis thereof, and has the effect of inhibiting and treating the tumors; and meanwhile, the PI3K has low toxicity.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of drugs for treating tumors, and in particular relates to a phosphatidylinositol-3-kinase inhibitor and its application as an anti-tumor drug. Background technique

[0002] Due to various reasons, the incidence of tumors has been increasing year by year. Statistics show that cancer has become the number one cause of death. In terms of tumor drugs, in 2005, the global sales of anti-cancer drugs totaled 28.2 billion US dollars, while the sales of anti-cancer drugs in my country are also increasing at an annual rate of 15% to 17%. , with an annual growth rate of more than 30%. Unfortunately, most of the antineoplastic drugs currently on the market are controlled by developed countries such as the United Kingdom and the United States, so actively developing new drugs with independent intellectual property rights has a very broad prospect.

[0003] The phosphatidylinositol 3-kinase (PI3K) signaling pathway is the main s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More