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Foot bathing effervescent tablets for warming and invigorating kidney deficiency

A technology for warming and tonifying kidney deficiency and effervescent tablets, which is applied to medical preparations containing active ingredients, drug delivery, and plant raw materials, etc., which can solve the problem of slow dissolution of active ingredients of drugs, inability to quickly and fully dissolve active ingredients, and lower bioavailability And other issues

Inactive Publication Date: 2011-10-05
GUANGDONG JIANDA LIGHTING ELECTRICAL APPLIANCE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current commercially available medicated bath pedicure products are all powder and bagged dosage forms, which are directly pulverized from the drug, and the active ingredients of the drug are slowly dissolved, especially at the water temperature acceptable to the human body. reduced bioavailability
[0004] In order to solve the technical problem that the effective ingredients of the medicine cannot be fully dissolved at the water temperature acceptable to the human body, the patent application published as CN1947684A discloses a "Muzu effervescent tablet", which comprises 20% of the total mass -40% organic acid, 20-40% sodium bicarbonate, 0.2-2.0% surfactant and 0.1%-5% lubricant, characterized in that: the traditional Chinese medicine Muzu effervescent tablet also contains Total mass 1-10% zedoary oil, 3-10% Sophora flavescens, 5-30% sodium chloride and appropriate amount of binder
The raw materials of traditional Chinese medicine in the scheme described in the above-mentioned patent application are zedoary oil and flavescens, as can be seen from the description in the instruction manual, the raw material of flavescens is just used as medicine after being pulverized, so although it is made into an effervescent tablet, it can make the tablet It dissolves rapidly when it meets water, but the active ingredients in Sophora flavescens raw material powder still cannot be dissolved quickly and fully at the water temperature acceptable to the human body

Method used

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  • Foot bathing effervescent tablets for warming and invigorating kidney deficiency
  • Foot bathing effervescent tablets for warming and invigorating kidney deficiency
  • Foot bathing effervescent tablets for warming and invigorating kidney deficiency

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] prescription:

[0045] Raw materials: actinolite 978g, cinnamon 582g, cnidium 894g, dodder 894g, gorgon 894g, rehmannia 1176g, cumin 582g;

[0046] Excipients: peppermint oil (appropriate amount), lemon 600g (calculated as anhydrous substance), sodium bicarbonate 780g, polyethylene glycol 6000 120g.

[0047] Preparation method:

[0048] The above seven flavors are crushed into fine powder and sieved; the remaining six herbs are decocted twice, adding 8 times the amount of water for the first time, and 6 times the amount of water for the second time, each time for 3 hours, and combining the second decoction , filtered, the filtrate was concentrated to a thick paste with a relative density of 1.28-1.32 (measured at 60°C), added 7 / 10 fine powder of rehmannia glutinosa, mixed evenly, dried at 80°C, crushed into fine powder, and sieved. Citric acid and sodium bicarbonate were dried separately, pulverized into fine powder, sieved, and set aside. Divide the above extract po...

Embodiment 2

[0050] prescription:

[0051] Raw materials: actinolite 600g, cinnamon 343g, cnidium 811g, dodder 1046g, gorgon 1280g, rehmannia 1387g, cumin 533g;

[0052] Excipients: citric acid 300g (calculated as anhydrous matter), fumaric acid 300g, sodium bicarbonate 480g, sodium carbonate 300g, polyethylene glycol 6000 100g, polyethylene glycol 4000 40g.

[0053] Preparation method:

[0054] The above seven flavors are crushed into fine powder and sieved; the remaining six medicinal materials are decocted twice, adding 10 times the amount of water for the first time, and adding 10 times the amount of water for the second time, each time for 2 hours, and combining the second decoction , filtered, the filtrate was concentrated to a thick paste with a relative density of 1.28-1.32 (measured at 60°C), added 7 / 10 fine powder of rehmannia glutinosa, mixed evenly, dried at 80°C, crushed into fine powder, and sieved. Citric acid, fumaric acid, sodium bicarbonate and sodium carbonate were dri...

Embodiment 3

[0056] prescription:

[0057] Raw materials: actinolite 862g, cinnamon 300g, cnidium 537g, dodder 820g, gorgon 1056g, rehmannia 1725g, cumin 700g;

[0058] Excipients: citric acid 300g (calculated as anhydrous matter), fumaric acid 300g, sodium bicarbonate 480g, sodium carbonate 300g, polyethylene glycol 6000 100g, polyethylene glycol 4000 30g, sodium lauryl sulfate 10g, manna Alcohol 100g, peppermint oil, rose oil (appropriate amount)

[0059] Preparation method:

[0060] The above seven flavors are crushed into fine powder and sieved; the remaining six medicinal materials are decocted twice, adding 6 times the amount of water for the first time, and adding 6 times the amount of water for the second time, each time for 1.5 hours, and combining the second decoction , filtered, and the filtrate was concentrated to a thick paste with a relative density of 1.28-1.32 (measured at 60° C.), added 6 / 10 Rehmannia glutinosa fine powder, mixed evenly, dried at 80° C., crushed into fin...

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Abstract

The invention relates to a Chinese medicinal compound preparation, in particular to foot bathing effervescent tablets for warming and invigorating kidney deficiency. The foot bathing effervescent tablets mainly comprise active ingredients, effervescent excipient and adhesive. The foot bathing effervescent tablets are characterized in that the active ingredient consists of 10 to 40 percent of prepared rehmannia rhizome powder and water extracts of the following raw material medicaments in percentage by weight: 8 to 30 percent of actinolite, 5 to 20 percent of cinnamon, 8 to 30 percent of common cnidium fruit, 8 to 30 percent of dodder, 8 to 30 percent of gordon euryale seed and 5 to 20 percent of fennel. The foot bathing effervescent tablets can adjust the functions of internal organs, andhave the effects of nourishing liver and kidney and warming and invigorating kidney deficiency.

Description

technical field [0001] The invention relates to medical preparations, in particular to a traditional Chinese medicine compound preparation. Background technique [0002] Kidney deficiency refers to that kidney vital essence negative and positive are not enough. There are many types of kidney deficiency referred to by traditional Chinese medicine, the most common of which are kidney-yin deficiency and kidney-yang deficiency. Symptoms of kidney deficiency: the symptoms of kidney yang deficiency are backache, cold limbs, chills, poor sexual function, and even edema, that is to say, the symptoms are "cold"; the symptoms of kidney yin deficiency are "hot", Mainly have backache, dry heat, night sweat, night sweat, dizziness, tinnitus and so on. Due to the high incidence of kidney deficiency, this requires that the means and methods of its prevention and treatment must be popularized to meet the needs of a large number of people with kidney deficiency. Therefore, it is an object...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61K9/46A61P1/14A61P15/08A61K33/26
Inventor 方永奇方惠新王淑英刘林
Owner GUANGDONG JIANDA LIGHTING ELECTRICAL APPLIANCE CO LTD