Chemical ionization reaction or proton transfer reaction mass spectrometry with a quadrupole or time-of-flight mass spectrometer

An ion and plasma technology, applied in the field of mass spectrometers, can solve the problems of not being able to positively identify specific compounds or substances, noise discrimination, etc., to promote quantitative measurement and/or identification, increase sensitivity, avoid electrode corrosion and avoid stable effect
CN101855700AInactive Publication Date: 2010-10-06MKS INSTR INC
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
MKS INSTR INC
Publication Date
2010-10-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

A system and methods are described for generating reagent ions and product ions for use in a mass spectrometry system. Applications for the system and method are also disclosed for detecting volatile organic compounds in trace concentrations. A microwave or high-frequency RF energy source ionizes particles of a reagent vapor to form reagent ions. The reagent ions enter a chamber, such as a drift chamber, to interact with a fluid sample. An electric field directs the reagent ions and facilitates an interaction with the fluid sample to form product ions. The reagent ions and product ions then exit the chamber under the influence of an electric field for detection by a mass spectrometer module. The system includes various control modules for setting values of system parameters and analysis modules for detection of mass and peak intensity values for ion species during spectrometry and faults within the system.
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Description

technical field

[0001] The present invention relates generally to mass spectrometers, and more particularly to mass spectrometry using microwave or high frequency radio frequency plasma to form reagent ions and applications thereof. Background technique

[0002] Mass spectrometry generally refers to the direct measurement of particle mass values ​​or the unambiguous determination of particle mass values ​​by measuring other physical quantities using spectral data. Mass spectrometers are often involved in determining the mass-to-charge ratio of ionized molecules or components. When the charge of an ionized particle is known, the particle's mass value can be determined from the spectrum of mass values.

[0003] Systems for performing mass spectrometry are known as mass spectrometers. A mass spectrometer system generally includes an ion source, a mass filter or separator, and a detector. For example, a sample of molecules or components can be ionized by affecting electrons i...

Claims

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