Unlock instant, AI-driven research and patent intelligence for your innovation.

Chinese medicinal composition for treating hepatic fibrosis and preparation method

A liver fibrosis and composition technology, which is applied in the field of traditional Chinese medicine compositions for treating liver fibrosis, can solve the problems such as the inability to use Huang Huangcao and Cordyceps sinensis together, and the lack of Gan Huangcao extract and Cordyceps sinensis liver fibrosis, etc., and achieve a synergistic effect. Accurate, good therapeutic effect, simple prescription effect

Active Publication Date: 2011-12-21
HANGZHOU HUADONG MEDICINE GRP PHARMA RES INST +2
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the prior art, there is no bibliographic report on the combined use of C. chinensis and Cordyceps sinensis, and there is no report on the prevention and treatment of liver fibrosis by the combination of C.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chinese medicinal composition for treating hepatic fibrosis and preparation method
  • Chinese medicinal composition for treating hepatic fibrosis and preparation method
  • Chinese medicinal composition for treating hepatic fibrosis and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Capsule preparation 1

[0024] Take fermented cordyceps mycelium powder produced by Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. under 60 meshes, and use QLM-150KA fluidized bed collision type jet mill with frequency modulation range of 50HZ and frequency of 32HZ to crush the cordyceps powder into Fine powder with particle size distribution below 75μ and average particle size below 15μ.

[0025] The stems (cut into sections) and leaves of the yellow grass, totaling 1000 g, were added with 6000 ml of ethanol with a concentration of 80% to extract twice, each for 1 hour, the extract was concentrated and spray dried.

[0026] Take 200 grams of Cordyceps micropowder prepared as above, 250 grams of Huangcao extract, add 47 grams of sucrose ester and 3 grams of magnesium stearate to mix, fill into hard capsules, and make 1000 capsules (0.5g / grain), that is Got.

Embodiment 2

[0028] Capsule preparation 2

[0029] With Huangcao and Cordyceps or fermented Cordyceps mycelium as the basic prescription, on this basis, the formula can be expanded according to the differentiation of TCM. For patients with obvious blood stasis, Danshen can be added.

[0030] A total of 750 g of the stems (cut into sections) and leaves of the yellow grass, 450 g of Salvia miltiorrhiza, add 7500 ml of 95% ethanol to extract once for 1 hour each time, the extract is concentrated and spray dried.

[0031] Take 85 grams of fermented Cordyceps fungus powder produced by Hangzhou Sino-US Huadong Pharmaceutical Co., Ltd. under 60 mesh; 140 grams of extracts of salvia miltiorrhiza, add 25 grams of micro-powdered silica gel, and fill in hard capsules to make 1000 tablets (0.25 g / grain), that is.

Embodiment 3

[0033] Granule preparation

[0034] A total of 1200 g of the stems (cut into sections) and leaves of the yellow grass were extracted three times with 1200 ml of 20% ethanol for 2 hours each time. The extract was concentrated and spray dried.

[0035] Natural Cordyceps, after drying, powdered and passed through a 60-mesh sieve.

[0036] Take 1000g of Huahuangcao extract and 800g of natural cordyceps powder, add 3g of stevia, 60g of colloidal microcrystalline cellulose, 1137g of corn starch, mix well, granulate, dry, and divide into 1000 bags, 3g / bag, ready to get .

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese medicinal composition for treating hepatic fibrosis and a preparation method. In the Chinese medicinal composition disclosed in the invention, a pharmaceutic adjuvant is added into penthorum chinense pursh ethanol extract and Chinese caterpillar fungus or fermented Chinese caterpillar fungus mycelia serving as active ingredients to prepare various oral preparations. Pharmacodynamic experiments prove that the two medicinal materials are combined to have the synergic effect on the treatment of the hepatic fibrosis, and the Chinese medicinal composition can be used for preventing and treating the hepatic fibrosis.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating liver fibrosis. Background technique [0002] In many chronic diseases in my country, hepatitis caused by viral, alcoholism, drugs and other reasons is very common. Chronic liver damage caused by viral infection and alcoholism often causes liver fibrosis and cirrhosis. Considering the physiological characteristics and significance of liver tissue, as well as the importance of treating and preventing liver diseases, there is an urgent need to develop drugs for treating and preventing liver fibrosis. [0003] Liver fibrosis is a pre-pathological state in which damaged liver tissue in chronic liver diseases such as hepatitis cannot be repaired into normal tissue, but it can be transformed into fibrous tissue such as collagen as part of an adaptive response in the body. Serum hyaluronic acid (HA), laminin (LN), type III pr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61K36/815A61K36/537A61P1/16
Inventor 白海波傅旭春杨建科扈荣潘福生
Owner HANGZHOU HUADONG MEDICINE GRP PHARMA RES INST