Method for preparing anti-hyperosteogeny tablets

A technology of anti-bone hyperplasia and rhizoma drynaria, which is applied in the field of medicine, can solve the problems that it is difficult to cover up the bad taste of drugs, the time limit for dissolving pills is difficult to control, and the bad smell of drugs is not easy to cover up, and achieves good dissolution rate and bioavailability. The effect of small content difference and accurate dosage

Inactive Publication Date: 2011-04-06
杨凌无为制药集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In solid preparations, powders and granules are not easy to cover the bad bitter taste of the drug, and they are easy to absorb moisture and are not easy to store, which affects the curative effect; when the capsule melts in the stomach, the local concentration of the drug is too high to stimulate the gastric mucosa, and some hygroscopic ingredients , because it can make the capsule wall too dry and brittle; the time limit for pill dissolution is difficult to control, and the production process is long, and it is easy to be contaminated by microorganisms, so that the pills grow mold and mold, and the bad smell of the drug is not easy to cover up

Method used

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  • Method for preparing anti-hyperosteogeny tablets
  • Method for preparing anti-hyperosteogeny tablets

Examples

Experimental program
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Effect test

Embodiment 1

[0031] (1) Take 204g rehmannia glutinosa, 136g chrysanthemum chrysalis, 136g rhizoma drynaria (hot), 136g Caulis Spatholobus, 136g cistanche, 136g epimedium, radish seed (stir-fried) 86g by weight;

[0032] (2) Get half of the amount of Miltonia Spatholobus described in step (1) and pulverize, then pass through a 100-mesh sieve;

[0033] (3) Boil Rehmannia glutinosa, Luniancao, Drynaria officinalis (hot), Cistanche, Epimedium, Laifuzi (fried), and the other half of the seven herbs of Spatholobus Spatholobus twice. The amount of water is 12 times of the total weight of the medicinal materials to be decocted, the decoction time is 3 hours, the amount of water added for the second decoction is 10 times of the total weight of the medicinal materials to be decocted, the decoction time is 2 hours, and the filtrate is combined after filtration. Concentrate to a thick paste with a relative density of 1.30 (50°C);

[0034] (4) Add the sifted Caulis Spatholobus in step (2) to the thick...

Embodiment 2

[0036] The preparation method of this example is the same as that of Example 1, except that the raw materials used are 254g of rehmannia glutinosa, 186g of Herba Ceratum, 186g of Rhizoma Drynariae (hot), 186g of Caulis Spatholobus, 186g of Herba Cistanche, and 186g of Epimedium 186g, radish seed (fried) 186g.

Embodiment 3

[0038]The preparation method of this example is the same as that of Example 1, except that the raw materials used are 154g Rehmannia glutinosa, 86g Rhizoma cerevisiae, 86g Rhizoma Drynariae (hot), 86g Caulis Spatholobus, 86g Cistanche, Epimedium 86g, radish seed (fried) 36g.

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Abstract

The invention discloses a method for preparing anti-hyperosteogeny tablets, which comprises the following steps of: crushing one half of suberect spatholobus stem and sieving, decocting the other half of suberect spatholobus stem, prepared rehmannia root, Chinese pyrola herb, burned fortune's drynaria rhizome, desertliving cistanche, epimedium herb and fried radish seed in water for two times, combining decocted filtrate, concentrating under reduced pressure to form thick paste, adding the crushed and sieved medicinal material into the concentrated thick paste, uniformly mixing, drying, crushing, adding auxiliary materials, uniformly mixing, pelleting, drying, tabletting and sugar-coating to obtain the anti-hyperosteogeny tablets. The anti-hyperosteogeny tablets prepared by the method have magic effect on hypertrophic spondylitis, cervical spondylosis, calcaneus spur, hypertrophic arthritis and kaschin beck disease, have higher dissolution rate and bioavailability than pills, have accurate dosage, stable quality, high yield and low cost, are convenient to take, carry, transport and the like, are suitable for mechanized production and easily meet the hygienic standard.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a preparation method of Kanggu hyperplasia tablet. Background technique [0002] Cervical spondylosis refers to a series of clinical symptoms and signs arising from the degenerative changes of the cervical spine and its subsidiary structures, which stimulate or compress relevant tissues. According to the location of the lesion and clinical manifestations, it can be divided into cervical type, nerve root type, spinal cord type, vertebral artery type, sympathetic type and mixed type. This disease belongs to the category of arthralgia, flaccidity, headache, dizziness and so on in traditional Chinese medicine. Osteoarthritis is a disease of movable joints characterized by degeneration or destruction of articular cartilage, subchondral bone sclerosis, osteophyte formation at the joint margins, and signs and symptoms of inflammation. This disease belongs to the category ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/20A61P19/08
Inventor 尹子郡
Owner 杨凌无为制药集团有限公司
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