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New purpose for compound aloes and new purpose-based medicament

A new use, the technology of aloe vera, applied in the treatment and/or prevention of hyperlipidemia complicated with cerebral infarction, the new use and the field of drugs for the new use, can solve the problems of poor safety, failure to effectively control blood sugar, and backward treatment methods for patients

Inactive Publication Date: 2011-04-27
JIANGSU WANBANG BIOPHARMLS +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Cerebral infarction caused by hyperlipidemia brings great pain to patients and their families, but most patients fail to effectively control blood sugar due to backward treatment methods and other reasons
At present, the clinical chemical lipid-lowering drugs mainly include statin, fibrate, resin, probucol, etc., all of which have certain defects, especially poor safety, so people have always been interested in finding a safe and effective modulation new drug

Method used

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  • New purpose for compound aloes and new purpose-based medicament
  • New purpose for compound aloes and new purpose-based medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Therapeutic Effect of Compound Aloe Capsules on Patients with Cerebral Infarction

[0020] Test subjects and groups:

[0021] Randomly selected 360 patients with cerebral infarction within 48 hours of onset, including 240 cases in the treatment group and 120 cases in the control group. All cases were treated with oral lipid-lowering drugs according to the condition to control blood lipids. Blood pressure was stabilized and small doses of dehydrating agents were used. , calcium antagonists (nimodipine), and platelet inhibitors (low-dose aspirin), anti-infection and other symptomatic treatment.

[0022] Treatment group: Take 2 compound aloe vera capsules orally, once a day, 28 days as a course of treatment;

[0023] Control group: oral administration of the same amount of placebo, once a day, 28 days as a course of treatment.

[0024] For those with severe conditions, 2 courses of treatment will be given.

[0025] Analytical Items and Treatments: Hemorheological Indexe...

Embodiment 2

[0032] Preventive Effect of Compound Aloe Capsules on Hyperlipidemia Complicated with Cerebral Infarction

[0033] 80 patients were randomly divided into two groups according to the random table generated by computer SPSS software.

[0034] The treatment group consisted of 40 cases, including 19 males and 21 females; age ranged from 58.5 to 83.5; neurological deficit scores ranged from 15 to 37, with an average of (23.2±7.5) points.

[0035] There were 40 cases in the control group, 22 males and 18 females; aged 54.5-85 years; the neurological deficit score ranged from 15 to 38 points, with an average of (22.5±6.6) points.

[0036] There was no significant difference between the two groups in terms of gender, age, and neurological deficit scores (P>0.05), and they were comparable. Both groups were given conventional treatment (OADs, dehydration medicine and supportive therapy, etc.). On this basis, the treatment group took 2 compound aloe capsules orally, once a day, for 28 ...

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PUM

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Abstract

The invention belongs to the field of pharmacy, and relates to a new purpose for compound aloes, a new purpose-based medicament, new use of the compound aloes in the preparation of medicaments for treating or preventing hyperlipidemia with cerebral infarction. The compound aloes can improve the hemorheological indexes of patients obviously, relieve the expression of the hyperlipidemia with cerebral infarction effectively, and improve the neural function, so the compound aloes are favorable for the recovery of the integral bodies of the patients from illness.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to a new application of compound aloe vera and a medicine for the new application for treating and / or preventing hyperlipidemia complicated with cerebral infarction. Background technique [0002] Compound aloe is mainly made of several kinds of traditional Chinese medicine raw materials such as aloe, Qingdai, cinnabar, and amber. The existing public documents include CN200810085002. The formula, preparation method, and mentioned that compound aloe vera has the functions of clearing the liver and purging heat, moistening the intestines and laxative, calming the mind and calming the nerves, and has significant curative effects on heart and liver fire, constipation, abdominal distension, abdominal pain, irritability and insomnia, etc., but for other There is no relevant report on the use of this aspect. [0003] Hyperlipidemia refers to the single or multiple levels of total cholesterol, trigl...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61P3/06A61P9/10A61K33/28A61K35/10
Inventor 高雪芹乔德水
Owner JIANGSU WANBANG BIOPHARMLS