Use of human fat-derived mesenchymal stem cells in treatment of diseases in kidney and ocular fundus

An adipose-derived, stem cell technology, applied in sensory diseases, animal cells, urinary system diseases, etc.
CN102048756BActive Publication Date: 2014-02-19微能生命科技集团有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
微能生命科技集团有限公司
Publication Date
2014-02-19

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Abstract

The invention relates to the use of human fat-derived mesenchymal stem cells in the treatment of diseases in kidney and ocular fundus. The invention provides the use of the human fat-derived mesenchymal stem cells in cell preparation for treating diseases in kidney and / or ocular fundus, such as acute kidney injury, renal fibrosis, renal tubular epithelial cell damage, retinosis, diabetic retinopathy and retinal tear. The cell preparation can promote the repair of kidney structure and damaged eyeball pathologic structure with good effect.
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Description

technical field

[0001] The present invention generally relates to the use of mesenchymal stem cells. Specifically, the present invention relates to the use of human adipose-derived mesenchymal stem cells in kidney and / or fundus diseases. Background technique

[0002] Mesenchymal stem cells (MSCs) are widely used in the research of various diseases due to their ability of self-renewal and multilineage differentiation. Human adipose-derived MSCs (hAD-MSCs) are easy to obtain, expand and have the same Source MSCs have similar differentiation potential and have become the most popular seed cells in the field of regenerative medicine in recent years.

[0003] Acute kidney injury and the resulting renal fibrosis are common clinical pathological processes. Whether it is a variety of primary glomerular diseases, or secondary kidney diseases such as diabetic nephropathy and lupus nephritis, they are closely related to the degree of renal fibrosis. These diseases can cause apoptosi...

Claims

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