Method and device for testing flowing property of blood flow at lesion site where blood vessel stent is implanted

A technology for testing device and flow performance, applied in the direction of blood flow measurement, etc.

Inactive Publication Date: 2011-05-25
SOUTHEAST UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, some scholars at home and abroad have carried out experimental research on the influence of stents on blood flow parameters after the stents are implanted in the lesion, and the methods used are mainly Doppler Velocimetry technology and particle image velocity measurement (Particle Image Velocimetry, PIV), in which Doppler velocity measurement technology has high requirements for the intensity of outgoing waves, and moving objects in the surrounding environment will affect the accuracy of measurement results
At the same time, the measurement accuracy is affected by the angle between the sound wave direction and the blood flow direction, and it is difficult to measure low-speed blood flow
Moreover, since the velocity field can only be drawn after the fixed sampling line and sampling points are measured and recorded one by one, it is difficult to achieve the transient measurement of the full flow field of blood flow, and the resolution is not high enough

Method used

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  • Method and device for testing flowing property of blood flow at lesion site where blood vessel stent is implanted
  • Method and device for testing flowing property of blood flow at lesion site where blood vessel stent is implanted
  • Method and device for testing flowing property of blood flow at lesion site where blood vessel stent is implanted

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Embodiment Construction

[0014] The test section includes a simulated vessel, stent, anode and cathode. Among them, the simulated blood vessel is a specially made transparent silicone tube containing part of the stenosis, so as to simulate the human blood vessel containing the stenosis. The wall shear stress at the point to be measured is measured by electrochemical method. The stainless steel tube is used as the anode and also as part of the circuit. The nickel-titanium probe is placed as the cathode at the point to be measured, and potassium ferricyanide (K 3 Fe(CN) 6 ), potassium ferrocyanide (K 4 Fe(CN) 6 ) solution is the electrolyte, and sodium hydroxide (NaOH) is the auxiliary electrolyte. According to the electrochemical principle, starting from 0 volts, gradually increasing the voltage between the anode and the cathode, at this time the current flowing between the anode and the cathode will also gradually increase, when the current no longer increases with the increase of the voltage When...

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Abstract

The invention discloses a device and a method for testing the flowing property of a blood flow at a lesion site where a blood vessel stent is implanted, which are used for testing the influences of the stent on the blood flow after the stent is implanted into a blood vessel. The method mainly comprises the measurement of wall shearing stress and the observation of fluid disturbance, wherein the wall shearing stress is measured by an electrochemical process, and the disturbance of the fluid is observed by using a camera. The device comprises a water tank and a peristaltic pump, wherein the outlet of the peristaltic pump passes through a buffer tank, a one-way regulating valve, a flow meter, a pressure transmitter and a test section in turn, the outlet of the test section is connected with the inlet of the water tank by a pipe and thus, a closed circulating system is formed. A light source is arranged on one side of the test section, and a camera which is connected with a computer is arranged on the other side of the test section. The pressure of the circulating system can be regulated by a pressurizing device connected with the water tank, the flow in the test section is regulated by the one-way regulating valve and the peristaltic pump, and the flow pressure transmitter and the flow meter are connected with the computer respectively.

Description

technical field [0001] The invention belongs to the technical field of performance testing of medical devices, and in particular relates to a test of the influence of a blood vessel stent on blood flow parameters and the like after being implanted in a lesion. Background technique [0002] Cardiovascular and cerebrovascular diseases have been recognized all over the world as one of the most serious diseases that endanger human life and health, and the morbidity and mortality of coronary heart disease rank first among all kinds of diseases. At present, the treatment of coronary heart disease is divided into three categories: drug therapy, surgical operation and interventional therapy. Interventional therapy is more and more popular because of its advantages of less bleeding, less trauma, fewer complications, safety and reliability, and quick postoperative recovery. attention. With the extensive use of stents, the side effects of interventional therapy have gradually emerged,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/026
Inventor 李俐军程洁易红倪中华
Owner SOUTHEAST UNIV
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