Whole human TNF alpha (tumor necrosis factor alpha) monoclonal antibody and preparation and application thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- 优锐生物医药科技(深圳)有限公司
- Publication Date
- 2013-06-19
Smart Images
Figure 1
Abstract
Description
technical field
[0001] The invention relates to the field of biotechnology, in particular to a TNFα-binding protein and its application. Background technique
[0002] Autoimmune diseases are the third largest group of diseases after cancer and cardiovascular diseases. Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. The prevalence rate of rheumatoid arthritis in my country is about 0.32-0.36%, and the incidence rate among people over 60 years old is as high as 30%-40%. Faced with hundreds of thousands of yuan per person per year for imported drug treatment, patients often have to endure painful chemical treatment for a long time, but with little effect.
[0003] RA has a large number of patients and a large amount of medication, which makes the market for therapeutic drugs huge. In 2005, the global market reached 6 billion US dollars. At present, there are many clinical treatment options for RA. The first choice is to use high-dose non-steroidal ant...