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Medicament for treating gynecological inflammation and preparation method thereof

A technology for gynecological inflammation and external use of drugs, applied in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of insignificant effect and slow onset of action, and achieve no toxic side effects, rapid absorption, high surface area active effect

Active Publication Date: 2012-07-04
金日制药(中国)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treatment of pure Chinese medicine has the disadvantages of slow onset of effect and inconspicuous effect.

Method used

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  • Medicament for treating gynecological inflammation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Add 60.0g of Fructus Cnidii, 45.0g of Phellodendron Phellodendri, 45.0g of Sophora Sophora and 45.0g of Peptalis, decoct twice with water, filter, combine the filtrate, concentrate the filtrate to an appropriate amount, adjust the alcohol content to 50% with ethanol, and precipitate with alcohol for 24 hour, get the supernatant and concentrate to an appropriate amount to obtain the extract of traditional Chinese medicine; chlorhexidine acetate 1.0g, borneol 1.0g, menthol 1.0g, vitamin E 1.0g, add medicinal 95% ethanol 20ml to dissolve, and stir Add 10ml of Tween 80, stir thoroughly, then add 500ml of purified water, mix evenly, gradually add the concentrated solution, 100ml of foaming agent, and 20ml of moisturizing agent while stirring, and finally add purified water to make up to 1000ml, and mix well to obtain The total mixture is filtered and loaded into a hand-pressed foam emulsion generating device.

[0020] It has been confirmed by the Fujian Provincial Center for...

Embodiment 2

[0027] Add 80.0g of Cnidium Fructus Cnidii, 50.0g of Cortex Phellodendri, 30.0g of Sophora Sophora, and 50.0g of Peptalis, decoct twice with water, filter, combine the filtrate, concentrate the filtrate to an appropriate amount, adjust the alcohol content to 50% with ethanol, and precipitate with alcohol for 24 hour, get the supernatant and concentrate to an appropriate amount to obtain the extract of traditional Chinese medicine; chlorhexidine acetate 2.0g, borneol 3.0g, menthol 4.0g, vitamin E 3.0g, add medicinal 95% ethanol 20ml to dissolve, and stir Add 3010ml of Tween, stir thoroughly, then add 500ml of purified water, mix evenly, gradually add the concentrated solution, 20ml of foaming agent, and 10ml of moisturizing agent while stirring, and finally add purified water to make up to 1000ml, and mix well to obtain The total mixture is filtered and loaded into a hand-pressed foam emulsion generating device. A clinical test of the prepared foam lotion on patients with genit...

Embodiment 3

[0029] Add 30.0g of Fructus Cnidii, 30.0g of Phellodendron Phellodendri, 80.0g of Sophora Sophora and 30.0g of Radix Papaya, decoct twice with water, filter, combine the filtrate, concentrate the filtrate to an appropriate amount, adjust the alcohol content to 50% with ethanol, and precipitate with alcohol for 24 After 1 hour, take the supernatant and concentrate to an appropriate amount to obtain the extract of traditional Chinese medicine; chlorhexidine acetate 1.5g, borneol 4g, menthol 3.0g, vitamin E 2.0g, add medicinal 95% ethanol 20ml to dissolve, add in stirring Tween 5010ml, stir well, then add 500ml purified water, mix evenly, gradually add concentrated solution, foaming agent 100ml, moisturizer 80ml while stirring, finally add purified water to make up to 1000ml, mix well to get the total mixture , filtered, and loaded into a hand-pressed foam emulsion generating device. A clinical test of the prepared foam lotion on patients with genital itching, vaginitis and cervi...

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PUM

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Abstract

The invention provides a medicament for treating gynecological inflammation, which comprises the following components in parts by weight: 5 to 30 parts of common cnidium fruit, 4 to 30 parts of golden cypress, 4 to 30 parts of lightyellow sophora root, 5 to 30 parts of sessile stemona root, 0.1 to 2 parts of borneol, 0.1 to 2 parts of menthol, 0.1 to 2 parts of chlorhexidine acetate, and 0.1 to 2parts of vitamin E. Compared with the prior art, the invention adopts a compound preparation consisting of classical Chinese medicaments and western medicaments, and has the characteristics of quickly killing pathogenic bacteria of western medicaments as well as diminishing inflammation and resisting bacteria of Chinese medicaments. Microbiological experiments and toxicant experiments prove that:the Chinese medicinal preparation has an excellent killing effect on pathogenic bacteria causing gynecological inflammation, such as staphylococcus aureus, candida albicans, escherichia coli and other pathogens, has the effects of treating female pruritus vulvae, has an accurate curative effect, low toxic or side effect, excellent functions of inflammation diminishing, sterilization and itching relieving.

Description

technical field [0001] The invention relates to a medicine for treating gynecological inflammation and a preparation method thereof. Background technique [0002] Gynecological inflammation is a common disease of women, mainly refers to the inflammation of female reproductive organs, including female pelvic inflammatory disease, adnexitis, cervicitis, vaginitis, urethritis, etc. caused by various reasons. [0003] Modern medicine believes that vaginitis is mainly caused by the invasion of bacteria and parasites or the imbalance of vaginal flora, including trichomonal vaginitis, fungal vaginitis, bacterial vaginosis, gonococcal vaginitis, etc. Gynecological inflammation can spread To the adjacent organs such as the cervix, uterus, and appendages, causing infection and chronic inflammation can also cause infertility or miscarriage. [0004] At present, Western medicine mostly adopts systemic anti-inflammatory plus local anti-inflammatory treatment. Although this method can t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61P15/00A61K31/045A61K31/155A61K31/355
CPCY02A50/30
Inventor 李仲树李冠华李冠嘉周丽娟赖荣胜王英
Owner 金日制药(中国)有限公司