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Extraction method of pachymaran

A technology for extracting polysaccharides from Poria cocos, which is applied in the field of extracting effective components of Chinese herbal medicines, can solve problems such as cumbersome extraction procedures, long time consumption, and severe extraction reactions, and achieve easy control of process conditions, increased yield, and mild reaction conditions. Effect

Inactive Publication Date: 2011-09-21
周明扬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The water extraction and alcohol precipitation method takes a long time and the extraction rate of polysaccharides is low; the leaching procedure of pachyrhin with acid and alkali solution is cumbersome and the leaching reaction is more violent, which easily destroys the three-dimensional structure of polysaccharides and limits its biological activity.

Method used

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  • Extraction method of pachymaran
  • Extraction method of pachymaran

Examples

Experimental program
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Embodiment 1

[0033] The extraction of embodiment 1 Poria cocos polysaccharide

[0034] process such as figure 1 as shown,

[0035] method of extraction:

[0036] 1. The Poria cocos raw material is superfinely pulverized to obtain Poria cocos powder:

[0037] According to the batch production instruction, get the required dried Poria cocos decoction piece raw material 100kg.

[0038] The qualified dried Poria cocos decoction pieces are crushed into particles of about 0.5 cm, and ultra-fine pulverized for 10 minutes, so that the fineness of Poria cocos powder reaches below 3 microns.

[0039] 2. Enzymatic extraction:

[0040] Composite enzyme: It is composed of cellulase, hemicellulase, amylase and papain, the ratio of which is 5:3:2:1. Enzymatic hydrolysis and extraction: add 12 times the weight of Poria cocos raw material for the first time, adjust the pH value of the extraction water to 5.0-6.0, start the stirring paddle, stir at a speed of 30 rpm, add mixed enzymes, and use an amoun...

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Abstract

The invention discloses an extraction method of pachymaran, comprising the following steps of: performing ultrafine grinding on a tuckahoe raw material to obtain tuckahoe powder; performing enzymatic extraction to obtain filtrate; concentrating the filtrate until the specific gravity is 1.05-1.10, then filtering, and drying the filtrate to obtain pachymaran. The extraction method of pachymaran disclosed by the invention has easy-to-control process conditions, can improve the yield to 25%, and has the advantages of mild reaction conditions, no toxic and side effect of reaction products and the like.

Description

technical field [0001] The invention relates to the extraction of effective components of Chinese medicinal materials, in particular to a method for extracting Poria cocos polysaccharide. Background technique [0002] Poria cocos, English name: Indian Buead, Tuckahoe, Latin name: Wolfiporia cocos (Schw.) Ryv.&Gibn, alias: Poria cocos, Poria cocos, Poria cocos, Poria cocos, Poria cocos, Song Yu, Yunling, Poria rabbit, Pine Potato, pine cassava, pine Ling. It belongs to the order Aphyllophorales, Polyporaceae, and Wolfiporia. [0003] The dried sclerotia of Poria cocos, its main active ingredient is polysaccharides, mainly pachyman, with a content of up to 75%, which is a kind of polysaccharide with β (1→6) glucopyranose branched chain. β(1→3) glucopyranose, cut the branched chain into β(1→3) glucopyran, called pachymaran, often called pachymaran (PPS), has antitumor activity, inhibits It has various functions such as tumor growth, anti-inflammation, anti-aging, regulation ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P19/14C08B37/00C12R1/645
Inventor 周明扬
Owner 周明扬
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