Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Absorbable bone screw and preparation method thereof

A bone screw, nano calcium carbonate technology, applied in medical science, surgery, etc., can solve the problems of aseptic inflammation, decreased mechanical properties, affecting tissue repair, etc., and achieves enhanced degradability, large specific surface area, and increased strength. Effect

Inactive Publication Date: 2011-11-23
ZHONGAO HUICHENG TECH CO LTD
View PDF6 Cites 30 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as the degradation time increases, the mechanical properties of this screw decrease too quickly; the acidic substances produced during the degradation process will cause aseptic inflammatory reactions in the tissue and affect tissue repair.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] 1) Dissolve 2.0 g of L-polylactic acid with an average molecular weight of 200,000 in 20 ml of dioxane at 50° C. to form a solution A with a concentration of 10% g / ml;

[0015] 2) 0.5g average particle diameter is that the calcium carbonate of 20 nanometers is joined in the 10 milliliters of stearic acid ethanol solution that concentration is 20% gram / ml, and the concentration of nanometer calcium carbonate in stearic acid ethanol solution is 5% gram / ml milliliter, processed at 50°C for 50 minutes, filtered out the powder, and dried to form surface-modified nano-calcium carbonate;

[0016] 3) adding the surface-modified nano-calcium carbonate to the solution A prepared in step 1), stirring and ultrasonically dispersing to form a suspension B;

[0017] 4) Prepare the suspension B in step 3) into thin slices with a thickness of 1mm by casting method, dry at 40°C, and then pulverize into granular materials, add them to an injection molding machine and inject them into a mo...

Embodiment 2

[0019] 1) Dissolve 2.0 g of D-polylactic acid with an average molecular weight of 100,000 in 20 ml of dioxane at 60° C. to form a solution A with a concentration of 10% g / ml;

[0020] 2) 0.11g average particle diameter is that the calcium carbonate of 100 nanometers is joined in the 10 milliliters of stearic acid ethanol solution that concentration is 10% gram / ml, and the concentration of nanometer calcium carbonate in stearic acid ethanol solution is 1.1% gram / ml milliliter, processed at 75°C for 10 minutes, filtered out the powder, and dried to form surface-modified nano-calcium carbonate;

[0021] 3) adding the surface-modified nano-calcium carbonate to the solution A prepared in step 1), stirring and ultrasonically dispersing to form a suspension B;

[0022] 4) Prepare the suspension B in step 3) into thin slices with a thickness of 2mm by casting method, dry at 100°C, and then pulverize into granular materials, add them to an injection molding machine and inject them into...

Embodiment 3

[0024] 1) Dissolve 2.0 g of racemic polylactic acid with an average molecular weight of 1.2 million in 40 ml of dioxane at 20° C. to form a solution A with a concentration of 5% g / ml;

[0025] 2) 1.33g average particle diameter is that the nano-calcium carbonate of 200 nanometers is joined in the 10 milliliters of stearic acid ethanol solution that concentration is 15% gram / ml, and the concentration of nano-calcium carbonate in stearic acid ethanol solution is 13.3% gram / ml, processed at 20°C for 600 minutes, filtered out the powder, dried to form surface-modified nano-calcium carbonate;

[0026] 3) adding the surface-modified nano-calcium carbonate to the solution A prepared in step 1), stirring and ultrasonically dispersing to form a suspension B;

[0027] 4) Prepare the suspension B in step 3) into a thin sheet with a thickness of 5mm by casting method, dry at 130°C, and then crush it into granular material, add it to the injection molding machine and inject it into a mold...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle sizeaaaaaaaaaa
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to View More

Abstract

The invention discloses an absorbable bone screw and a preparation method thereof. The absorbable bone screw comprises: by mass, 5 to 40% of nanoscale calcium carbonate and 95 to 60% of a polylactic acid. The preparation method comprises mixing nanoscale calcium carbonate powder and a polylactic acid in a solution form, uniformly dispersing the nanoscale calcium carbonate powder in a polymer matrix through a rapid tape-casting drying method, and carrying out a molding process by an injection molding machine. The absorbable bone screw has the advantages of good biological activity and degradability, and high strength.

Description

technical field [0001] The invention belongs to a composite material for bone and tendon repair and a preparation method thereof, in particular to an absorbable nano calcium carbonate reinforced bone screw and a preparation method thereof. Background technique [0002] Bone screws are used for the fixation of fractures and grafted materials, and are traditionally made of metal materials. In recent years, the number of screws made of degradable polymer materials has gradually increased. Its biggest feature is that it can degrade after being implanted in the human body. As the tissue heals, the implant slowly degrades. After the tissue heals, the implant is completely absorbed. Ashamed, so no second surgery. However, as the degradation time increases, the mechanical properties of this screw decrease too quickly; the acidic substances produced during the degradation process will cause aseptic inflammatory reactions in the tissue and affect tissue repair. Introducing inorganic...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/14A61L31/12A61L31/02A61L31/06
Inventor 金攻李众利翁文剑胡影李新宇
Owner ZHONGAO HUICHENG TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com