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Application of Probiotic Factor and Lactobacillus Mixture in Prevention and Treatment of Vaginitis

A technology of probiotics and lactic acid bacteria, applied in the field of probiotics and lactic acid bacteria, can solve the problems of no number of probiotics, treatment failure, etc.

Inactive Publication Date: 2011-11-30
上海杜伊特医疗器械有限公司 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, the single use of probiotic factors may encounter the situation that some patients have no probiotics in the vagina or the number of probiotics is too small, resulting in treatment failure

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0020] Embodiment 1 2 3 4 5 6

[0021] Lactobacillus 30 30 30 40 40 40

[0022] Chitosan 10 10-10 0-

[0023] Fructooligosaccharide 10 10----

[0024] Xylooligosaccharides 10 10 10 20-15

[0025] Galactooligosaccharide 10-10-10 10

[0026] Stachyose 10 10---10

[0027] Chitooligosaccharides 10 10 10 20 20 10

[0028] Pharmaceutical excipients 10 20 40 10 30 15

[0029] The specific preparation method of the above embodiment of the present invention is:

[0030] Take appropriate amount of sterile water, dissolve all the sugars that need to be added in sterile water in turn, filter and sterilize with a filter membrane to obtain a sterilized sugar solution. Lyophilize in vacuum. Add Lactobacillus and mix well. Add pre-prepared pharmaceutical excipients to prepare a suitable preparation form.

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PUM

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Abstract

The invention relates to the application of a probiotic factor and lactobacillus mixture in preventing and treating vaginitis. Prebiotic factors can promote the reproduction of beneficial bacteria Lactobacillus and Bifidobacteria in women's vagina, and inhibit the growth of vaginal pathogenic bacteria through space occupation competition and secretion of hydrogen peroxide. At the same time, the reproduction of Lactobacillus can maintain the weak acidic environment of the vagina and adjust the pH value of the vagina. The addition of Lactobacillus can effectively supplement vaginal probiotics, help probiotics multiply rapidly, and occupy the dominant position in the structure of vaginal flora. Through the effective combination of probiotic factors and lactobacilli, the present invention has remarkable efficacy in preventing and treating vaginitis, especially recurrent vaginitis.

Description

Technical field [0001] The present invention relates to probiotic factors and lactic acid bacteria, in particular to the application of probiotic factors and lactic acid bacteria mixture in the prevention and treatment of vaginitis. Background technique [0002] Vaginitis is a common disease faced by women throughout their lives. At present, the treatment of vaginitis mainly relies on antibiotics and chemical synthetic drugs, which kill pathogenic bacteria while also killing beneficial bacteria. After cure, the structure of vaginal flora is fragile and vaginitis Easy to relapse. There is a need for a more effective method to kill pathogenic bacteria. At the same time, the frequent use of antibiotics and chemical synthetic drugs leads to the emergence of drug resistance, which makes the treatment of vaginitis time-consuming and laborious, and the effect is not good. [0003] At present, some products at home and abroad use microecology knowledge and use Lactobacillus preparations ...

Claims

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Application Information

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IPC IPC(8): A61K35/74A61P15/02A61K31/702A61K31/722A61K35/747
Inventor 邢建慧赵小宁
Owner 上海杜伊特医疗器械有限公司
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