A ccd-type colloidal gold immunochromatographic diagnostic test paper quantitative analysis system

A technology of immunochromatography and quantitative analysis, which is applied in the direction of material analysis, material analysis through optical means, and measuring devices, etc. It can solve problems such as inability to quantitatively analyze, facilitate function upgrades and expansions, solve subjective deviations, and ensure stability Effect

Inactive Publication Date: 2011-12-14
杭州顿力医疗器械有限公司
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

Every time the machine is turned on, it is necessary to manually operate the standard color plate to calibrate the system; in addition, the photodiode is used as the signal acquisition component, which cannot perform accurate quantitative analysis, and only the test strip products provided by the manufacturer can be used

Method used

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  • A ccd-type colloidal gold immunochromatographic diagnostic test paper quantitative analysis system
  • A ccd-type colloidal gold immunochromatographic diagnostic test paper quantitative analysis system
  • A ccd-type colloidal gold immunochromatographic diagnostic test paper quantitative analysis system

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Embodiment 1

[0035] Embodiment 1: with reference to attached Figure 1-11 . A CCD-type colloidal gold immunochromatography diagnostic test paper quantitative analysis system is composed of an image collector, a data processor, and a result output device; the main board signal exchange terminal in the data processor is respectively connected with the image processing and reading software and the image collector Two-way data exchange with industrial cameras in the camera. The image collector consists of a target tray, an LED lighting chamber, an optical flat mirror, and an industrial camera. The receiving surface and the reflecting surface of the optical flat mirror are distributed at 45 degrees, and the LED lighting chamber located under the optical flat mirror illuminates the measured target. The light on the surface is vertically reflected to the 45-degree distributed optical plane reflector and the measured target image is reflected to the industrial camera lens through the 45-degree di...

Embodiment 2

[0066] Embodiment 2: On the basis of embodiment 1, a kind of CCD type colloidal gold immunochromatography diagnostic test paper quantitative analysis method, light is sent by LED lighting chamber, is irradiated on the test paper strip after reaction, diffuses through the test paper surface After reflection, the light is reflected by the optical flat mirror to the industrial camera, and the digital image is captured by the industrial camera, and then sent to the computer software for analysis and processing, and finally the reading values ​​of the test line and the quality control line on the colloidal gold immunochromatography diagnostic test strip are obtained. On the test line and quality control line of the test strip, due to the light absorption characteristics of gold nanoparticles, the scattered light signal at the test line - T line and quality control line - C line will be smaller than that of other areas of the test strip. Signal, after analyzing the brightness of the ...

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Abstract

The invention relates to a CCD-type quantitative analysis system of colloidal gold immunity chromatography diagnosis test papers and an analysis method. According to the invention, a CCD digital image technology is used for carrying out instant shooting, processing and reading upon tested targets. The system comprises an image collecting device, a data processing device, and a result outputting device. Bilateral handshaking is respectively carried out between a motherboard handshaking terminal and image processing and reading software, and between a motherboard handshaking terminal and an industrial camera in the image collecting device. The system and the method are advantaged in that: an illumination light source with a patent technology, a self calibrate algorithm, and an image noise reduction algorithm are adopted, such that the stability, consistency and accuracy of reading results can be effectively ensured, and subjective deviation caused by human eye interpretation can be solved; an integral industrial control computer application architecture, with which the invention applied for an independent intellectual property right, is integrated in the instrument system; the parts such as modularized LED illumination, CCD camera, data processing system, can be selected according to user requirements of different performances and prices; according to the invention, parts of the software are developed on a mainstream Windows platform, such that subsequent function upgrading and expanding can be promoted.

Description

technical field [0001] The invention relates to a CCD-type colloidal gold immunochromatographic diagnostic test paper quantitative analysis system and analysis method that adopts CCD digital image technology to instantly photograph, process and read the detected target, and is suitable for colloidal gold such as early pregnancy, influenza and drugs. Rapid determination of the results of immunochromatographic diagnostic test strips. Background technique [0002] Currently, there are various colloidal gold immunochromatographic diagnostic test strip analysis systems or instruments on the market. Similar instruments or equipment introduced by foreign manufacturers such as GEM Premier have high precision, good stability and are easy to use. But it is only applicable to specific types of test strip products (mostly bundled with the test strips produced by the manufacturer). South Korea's i-CHROMA Reader immunofluorescence analyzer has a detection sensitivity of pg / ml, but the p...

Claims

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Application Information

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IPC IPC(8): G01N33/558G01N21/31G01N21/84
Inventor 朱新宇
Owner 杭州顿力医疗器械有限公司
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