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Chinese and western medicinal compound preparation for preventing and treating bullfrog streptococcus agalactiae diseases and preparation method

A technology of Streptococcus galactiae and compound preparation, which is applied in the directions of antibacterial drugs, pharmaceutical formulations, medical preparations containing active ingredients, etc. high rate and mortality

Inactive Publication Date: 2013-04-03
ZHEJIANG INST OF FRESH WATER FISHERIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The infection rate and mortality rate of bullfrog streptococcosis agalactiae are high, which has caused serious losses to the bullfrog breeding industry
The conventional treatment method for bullfrog agalactiae streptococcosis is chemical medicine plus antibiotics. Long-term use of antibiotics is likely to cause drug resistance of pathogenic microorganisms and lose the therapeutic effect, while Chinese herbal medicine has no residue and no drug resistance. Therefore, delete It is of great significance to prepare a compound preparation with rapid effect and long-lasting effect by combining the compatibility and curative effect of Chinese and Western medicines that have therapeutic effects on the disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Weigh gallnut 18%, andrographis paniculata 8%, rhubarb 17%, honeysuckle 15%, starch 32%, neomycin sulfate 10%, fineness requirement: 100 mesh, drying weight≤10.0%; Mix completely; add neomycin sulfate and stir evenly to obtain the compound preparation of traditional Chinese medicine and western medicine for preventing and treating bullfrog agalactiae streptococcosis.

Embodiment 2

[0027] Weigh Galla gall 22%, Andrographis paniculata 12%, Rhubarb 13%, Honeysuckle 17%, Starch 28%, Neomycin sulfate 8%, the fineness requirement is: 120 mesh, drying weight≤8.0%; Mix completely; add neomycin sulfate and stir evenly to obtain the compound preparation.

Embodiment 3

[0029] Weigh Galla gall 20%, Andrographis paniculata 5%, Rhubarb 15, Honeysuckle 10%, Neomycin sulfate 15%, Starch 35%, the fineness requirement is: 80 mesh, drying weight ≤ 10.0%; Stir the Chinese medicine ingredients mixed with starch until completely Mix; add neomycin sulfate and stir evenly to obtain the compound preparation.

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PUM

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Abstract

The invention relates to a Chinese and western medicinal compound preparation for preventing and treating bullfrog streptococcus agalactiae diseases and a preparation method, and belongs to the technical field of fish medicines. The Chinese and western medicinal compound preparation is characterized by consisting of the following substances in percentage by weight: 15 to 25 percent of Chinese gall, 5 to 15 percent of common andrographis herb, 10 to 20 percent of rhubarb, 10 to 20 percent of honeysuckle flower, 5 to 15 percent of neomycin sulfate and 25 to 35 percent of starch. The Chinese andwestern medicinal compound preparation is prepared by combining the neomycin sulfate which has a treatment effect on germs and serves as a western medicine, the Chinese gall, the common andrographis herb, the rhubarb and the honeysuckle flower which serve as Chinese medicines and the starch serving as an auxiliary material, has obvious synergistic effect and high curative effect, lasting medicinal effect and low toxicity to the environment and can arouse quick response, and the tolerance is difficult to generate; and the preparation process is simple, easy to realize, safe and convenient to use, popularize and apply.

Description

technical field [0001] The invention belongs to the technical field of fish medicines, and specifically relates to a compound preparation of Chinese and western medicines for preventing and treating streptococcosis agalactiae of bullfrogs and a preparation method thereof. Background technique [0002] At present, streptococcus has become one of the main fish pathogenic bacteria, harming various freshwater and sea fish such as salmon trout, red sea bream, flounder, sweetfish, coho salmon, etc., with high mortality. The infection rate and mortality of bullfrog streptococcosis agalactiae are high, which has caused serious losses to the bullfrog breeding industry. The conventional treatment method for bullfrog agalactiae streptococcosis is chemical medicine plus antibiotics. Long-term use of antibiotics is likely to cause drug resistance of pathogenic microorganisms and lose the therapeutic effect, while Chinese herbal medicine has no residue and no drug resistance. Therefore, d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/708A61P31/04A61K35/64A61K31/7036
Inventor 周冬仁叶雪平罗毅志施伟达杭小英
Owner ZHEJIANG INST OF FRESH WATER FISHERIES
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