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Promoter for generation of glutathione

A technology of glutathione and accelerators, applied in the direction of anti-toxic agents, organic active ingredients, skin care preparations, etc., can solve the problems of not knowing

Inactive Publication Date: 2012-02-01
ARSOA HONSHA CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, it is not known to extract the extract from a plant belonging to the genus Saussurea, to isolate a prescribed component from an extract from a plant belonging to the genus Saussurea, or to belong to the genus Saussurea. Dihydrodehydrocostuslactone contained in plants of the genus is used as a glutathione production accelerator

Method used

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  • Promoter for generation of glutathione
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0042] The glutathione production accelerator according to Embodiment 1 contains "an extract derived from a plant belonging to the genus Saussurea" as an active ingredient (see figure 1 ).

[0043] In the glutathione production accelerator according to Embodiment 1, the "extract derived from a plant belonging to the genus Saussurea" includes: an extract obtained from a plant belonging to the genus Saussurea by extraction Any of an extract, a dilution or a concentrate of the extract, a dried product obtained by drying the extract, or a crude or refined product of the above-mentioned substances.

[0044] In the extraction process, a plant belonging to the genus Saussurea is used as an extraction raw material. The whole herb can be used as the raw material for extraction, but the aerial parts are preferably used.

[0045] Specific examples of plants belonging to the genus Saussurea include: Saussurea involucrata (Kar. et Kir.) Sch.Blp. or Tianshan Snow Lotus), Jellyfish Snow R...

Embodiment approach 2

[0064] The glutathione production accelerator according to Embodiment 2 contains the following component as an active ingredient: "dissolve an extract derived from a plant belonging to the genus Saussurea in 30% (V / V) methanol, Components adsorbed by porous polystyrene resin when the obtained solution flows through a column supported by porous polystyrene resin" (refer to figure 1 ).

[0065] The "extract derived from a plant belonging to the genus Saussurea" can be obtained by the method described in Embodiment 1 above.

[0066] Examples of the porous polystyrene resin that can be used as a carrier include DIAION (registered trademark of Mitsubishi Chemical Corporation) HP20 and HP21, and SEPABEADS (registered trademark of Mitsubishi Chemical Corporation) SP850, SP700, and SP70.

[0067] In addition, in Embodiment 2, the component adsorbed by the porous polystyrene resin is passed through the column after a solution dissolved in 30% (V / V) methanol is passed through the colum...

Embodiment approach 3

[0071] The glutathione production accelerator according to Embodiment 3 contains the following ingredient as an active ingredient: "the extract derived from a plant belonging to the genus Saussurea (Saussurea) was dissolved in 30% (V / V) methanol , when the obtained solution flows through a chromatographic column supported by porous polystyrene resin, and then 50% (V / V) methanol flows through the chromatographic column, the components adsorbed by the porous polystyrene resin" (refer to figure 1 ).

[0072] The "extract derived from a plant belonging to the genus Saussurea" can be obtained by the method described in Embodiment 1 above.

[0073] As a porous polystyrene resin used as a carrier, DIAION (registered trademark of Mitsubishi Chemical Corporation) HP20 and HP21, SEPABEADS (registered trademark of Mitsubishi Chemical Corporation) SP850, SP700, SP70 etc. are mentioned, for example.

[0074] Furthermore, in Embodiment 3, the component adsorbed by the porous polystyrene re...

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PUM

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Abstract

The invention provides ''a promoter for generation of glutathione obtaining ingredients from natural objects with high safety'', and provides ''pharmaceuticals, foodstuff, or cosmetics comprising the promoter for generation of glutathione and with glutathione generation promoting effect''. The promoter for generation of glutathione comprises a plant extract comprising Saussurea species, in particular an extract selecting from more than one plant of Saussurea involucrata (Kar.et Kir.) Sch.Blp.), Saussurea medusa Maxim.) and Saussurea laniceps Hand.-Mazz. as active ingredients.

Description

technical field [0001] The present invention relates to a glutathione production accelerator and pharmaceuticals, food or cosmetics having a glutathione production promotion effect. Background technique [0002] Glutathione is a tripeptide formed by three amino acids, glutamic acid, cysteine, and glycine. It is an antioxidant substance widely distributed in organisms. It is known that it captures free radicals, regulates cell functions through redox, As the SH group donor of various enzymes, participate in detoxification metabolism, etc. [0003] It is known that when the amount of glutathione in cells decreases, it is associated with cell damage caused by exposure to ultraviolet light, inflammation, acute or chronic alcoholic liver damage, liver disease, Parkinson's disease, Alzheimer's disease, gastric ulcer, Immunodeficiency, acquired immunodeficiency syndrome, aging phenomenon with physiological aging, canceration, etc. [0004] Therefore, if the amount of glutathione ...

Claims

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Application Information

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IPC IPC(8): A61K36/285A61K8/97A61K8/49A61K31/365A23L1/29A61Q19/00A61Q19/10A61P1/04A61P1/16A61P17/00A61P17/16A61P25/16A61P25/28A61P37/02A61P35/00A61P39/06A23L33/00
Inventor 坂本香清水崇之高桥知也三卷祥浩横须贺章人
Owner ARSOA HONSHA CORP
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