Preparation method for ionic liquid silica gel capillary monolithic column stationary phase

A technology of capillary monolithic column and ionic liquid, which is applied in the field of chromatographic stationary phase, can solve the problems that the ionic liquid silica gel capillary monolithic column has not been reported in literature, etc., and achieve the effect of simple preparation method, mild reaction conditions and good reproducibility
CN102500346AInactive Publication Date: 2012-06-20GUANGXI NORMAL UNIV
1 Cites 19 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GUANGXI NORMAL UNIV
Publication Date
2012-06-20
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention provides a preparation method for a novel ionic liquid silica gel capillary monolithic column stationary phase. The novel ionic liquid silica gel capillary monolithic column stationary phase is prepared by a sol-gel and gold nanoparticle surface functionalization technology. According to the characteristic that the gold nanoparticles have strong affinity on a ligand containing sulfydryl, amino and cyan and the excellent properties of the gold nanoparticles, the ionic liquid and the silica gel monolithic column, the prepared ionic liquid silica gel capillary monolithic column hasthe advantages of high selectivity, high column efficiency, simplicity in preparation, wide application rang and the like. An electropositive imidazole ring and an analyte have various kinds of interactions comprising a hydrophobic interaction, an ion exchange interaction, a pi-pi interaction, a dipolar interaction and a weak hydrophilic interaction and also have multiple action mechanisms such as a hydrogen bond action and the like. Therefore, the preparation method can be applied to separation analysis on hydrophobic neutral compounds, alkaline organic compounds, polar compounds and inorganic anions. The ionic liquid silica gel capillary monolithic column stationary phase can serve as a capillary electrochromatography or capillary liquid chromatography fixed phase and has good application potential in the field of separation science.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a chromatographic stationary phase, in particular to a preparation method of a novel ionic liquid silica gel capillary monolithic column stationary phase. Background technique

[0002] As a new chemical material, ionic liquid has the advantages of good thermal stability, low flammability, non-volatile and low toxicity, etc. It has been widely used in various fields and has attracted increasing attention of many researchers. In recent years, the application of ionic liquids in separation analysis has been reported in relevant literature, such as Li et al. (Jing Li, Haifeng Han, Qing Wang, Xia Liu, Shengxiang Jiang, J. Sep. Sci. 2011 , 34, 1555-1560) prepared capillary electrophoresis columns coated with poly-1-vinyl-3-butylimidazolium bromide salt. Qiu et al. (Hongdeng Qiu, Shengxiang Jiang, Xia Liu, Liang Zhao, J. Chromatogr. , 2006, 1116 , 46-50) prepared imidazolyl-based anion-exchange stationary phases for HPLC analysi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More