Metamaterial-based optical tweezers

A left-handed material, optical tweezers technology, applied in the direction of analyzing materials, material analysis by optical means, measuring devices, etc., can solve the problems of low molecular ability, poor sensitivity, high cost, reduce the influence of vitality and disturbance, and capture accuracy. High and stable effect

Active Publication Date: 2012-07-11
DALIAN UNIV OF TECH
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Problems solved by technology

However, it cannot operate on nanoscale particles, and the cost is high. For details, see: Advances in Lasers and Optoelectronics, 2007, 44(6): 15-26
[0005] The above-mentioned optical tweezers systems all belong to the struc

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Embodiment Construction

[0021] In order to make the content of the technical solution of the present invention clearer, the specific implementation manners of the present invention will be described in detail below in combination with the technical solution and the accompanying drawings. The thin film growth techniques include: evaporation, sputtering, metal organic chemical vapor deposition (MOCVD), molecular beam epitaxy (MBE), electron beam evaporation (E-beam evaporation) or liquid phase epitaxy (LPE) and other common techniques. The masking process includes electron beam lithography (E-beamlithography, EBL), focused ion beam lithography (Focus Ion Beam lithography, FIBL) and other common techniques. The etching process includes wet etching and dry etching, such as common processes such as acid etching, electron beam etching, focused ion beam etching and reactive ion etching (Reactive Ion Etching, RIE).

[0022] First, an N (N>=1) layer sandwich structure (metal layer-insulation layer-metal layer...

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Abstract

The invention provides metamaterial-based optical tweezers. By preparing a hole array with a periodic structure on one or more layers of sandwich structure including a metal layer, an insulating layer and another metal layer, the optical tweezers can have magnetic dipoles, and under the irradiation of a light source, a negative optical force along the illumination direction is generated, so micro-particles can be captured and selected accurately. With the magnetic dipoles, the optical tweezers can capture the micro-particles under the action of a low-power light source, and influence and interference of the optical tweezers on the activity of a biological sample caused by over-high power of the light source are reduced. The optical tweezers can have the characteristics of small volume, large capturing force, high stability and the like.

Description

technical field [0001] The invention belongs to the field of detection of biological samples (such as proteins, DNA and antibodies, etc.), relates to an optical tweezers based on left-handed materials, and can be applied to disease treatment and diagnosis and biomedicine. Background technique [0002] The development of life sciences provides efficient and convenient means for the diagnosis, treatment and prevention of diseases, but it also faces new challenges, that is, how to manipulate micro-sized tissues, cells, drugs, biomacromolecules and bioactive molecules, etc., to provide Instant, online, accurate and comprehensive analysis. In order to solve these problems, people try to organically combine the laser microbeam optical trap effect with bioengineering, microelectronics technology, and optoelectronics, thus forming a new hotspot in the field of biomedicine: optical tweezers technology. [0003] In 1986, Arthur Ashkin, a scientist at Bell Laboratories in the United S...

Claims

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Application Information

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IPC IPC(8): G01N21/84
Inventor 曹暾
Owner DALIAN UNIV OF TECH
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