Fingerprint measuring method of hopper pepper rheumatism paste and semi-finished product of hopper pepper rheumatism paste

A technology of fingerprints and determination methods, which is applied in the field of determination of fingerprints of traditional Chinese medicines, can solve problems such as lack of comprehensiveness, and achieve good repeatability

Inactive Publication Date: 2012-09-05
HENAN LINGRUI PHARMA
View PDF2 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the quality control of chili rheumatism ointment only has identification, ointment content determination and heat resistance. It is not comprehensive to control the quality of the product based on these indicators alone. For manufacturers, there is an urgent need for a drug that can be used in the production process of the drug. Methods of Monitoring Quality

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Fingerprint measuring method of hopper pepper rheumatism paste and semi-finished product of hopper pepper rheumatism paste
  • Fingerprint measuring method of hopper pepper rheumatism paste and semi-finished product of hopper pepper rheumatism paste
  • Fingerprint measuring method of hopper pepper rheumatism paste and semi-finished product of hopper pepper rheumatism paste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0049] 1. Instruments and reagents

[0050] Instrument: Shimadzu 2010 liquid chromatograph, including quaternary pump, online degassing device, autosampler, LC-solution workstation; acetonitrile is chromatographically pure, phosphoric acid and methanol are analytically pure, and purified water; 10 batches of capsicum rheumatism Paste semi-finished products; 10 batches of chili rheumatism paste preparations.

[0051] 2. Chromatographic conditions

[0052] Agilent C18 chromatographic column (250mm*4.6mm*5um); column temperature 35°C; flow rate 1ml / min; mobile phase A is 0.01% phosphoric acid water (0.1mL is added to 1000mL water); mobile phase B is acetonitrile, wavelength: 210nm, Gradient elution, the elution program is:

[0053] At 0min, mobile phase A: mobile phase B = 55:45

[0054] At 20min, mobile phase A: mobile phase B = 55:45

[0055] At 45min, mobile phase A: mobile phase B = 40:60

[0056] At 75min, mobile phase A: mobile phase B = 40:60

[0057] 3. Establishment ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
wavelengthaaaaaaaaaa
Login to view more

Abstract

The invention relates to a method for monitoring the quality of a hopper pepper rheumatism paste semi-finished product and a hopper pepper rheumatism paste finished product and discloses the fingerprint creating method of the hopper pepper rheumatism paste semi-finished product and the hopper pepper rheumatism paste finished product and the standard HPLC (High Performance Liquid Chromatography) fingerprint of the hopper pepper rheumatism paste semi-finished product and the hopper pepper rheumatism paste finished product. The method disclosed by the invention comprises the following steps: 1. taking a proper amount of test sample, adding methanol, ethanol or mixing at least one solvent in methanol and ethanol to extract a test sample solution; 2. creating the standard fingerprint of the hopper pepper rheumatism paste and the hopper pepper rheumatism paste semi-finished product through HPLC chromatography; and 3. comparing the fingerprint of the test sample with the standard fingerprint of the test sample, conveying the semi-finished products with qualified integral similarity to the next procedure, and delivering the finished products to be tested out of the factory as qualified products. The method disclosed by the invention has the advantages of simple and convenient method, good stability, high precision, good reproducibility, is capable of mastering the quality condition of the hopper pepper rheumatism paste from the integral characteristic condition of the chromatogram, so that the method can serve as the quality control index of the hopper pepper rheumatism paste.

Description

technical field [0001] The present invention relates to the determination method of the traditional Chinese medicine fingerprint of capsicum rheumatism ointment and its semi-finished product, more specifically, relates to the method for measuring the chemical composition of capsicum rheumatism ointment and its semi-finished product by high performance liquid chromatography (HPLC) fingerprint method. technical background [0002] Traditional Chinese medicine fingerprint refers to the spectrum or chromatogram composed of common and characteristic components in a certain Chinese medicinal material (extract, Chinese patent medicine). It is a comprehensive and quantifiable identification method. It is based on the systematic research on the chemical components of traditional Chinese medicine, and is mainly used to evaluate the authenticity, goodness and stability of the quality of Chinese medicinal materials and semi-finished products of traditional Chinese medicine preparations, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/36
Inventor 姜家书程剑军张春霞熊维政谢其亮李敦明武惠斌聂红梅
Owner HENAN LINGRUI PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap