Application of polysaccharides extracted from wild chrysanthemum in preparation of medicine for enhancing body immunity

Abstract

The invention belongs to the field of extraction of active medicinal ingredients for effectively enhancing body immunity from traditional Chinese medicinal materials. The technical scheme comprises the following steps of: preparing 500g of dried wild chrysanthemum medicinal materials, extracting in a water bath at 90 DEG C for 1 hour by using water as an extractant, continuously extracting for 3 times, filtering, combining the water extracts, concentrating, and then adding 95% ethanol which is 5 times of the concentrated extract, and standing for 24 hours; performing suction-filtration on precipitate obtained after ethanol precipitation, and then sequentially washing the precipitate with absolute ethanol, acetone and ethyl ether in sequence, and drying to obtain wild chrysanthemum crude polysaccharide powder; purifying the wild chrysanthemum crude polysaccharide powder by using LSA-21 macroporous adsorption resin, performing the same ethanol precipitation on the received solution to obtain relatively purified wild chrysanthemum polysaccharide powder, wherein the detection based on the anthrone-sulphuric acid method proves that the content of polysaccharides is 81.29%; preparing the wild chrysanthemum polysaccharide powder into wild chrysanthemum polysaccharide solution with concentration of 40-20 g.L<-1> by normal saline respectively during intragastric administration; and finally, combining the extracted wild chrysanthemum polysaccharides with common auxiliary materials to obtain various dosage forms of medicines for enhancing immunity.

Description

technical field [0001] The invention belongs to the extraction of medicinal active ingredients that can effectively improve the body's immunity from traditional Chinese medicinal materials, in particular the medical application of using polysaccharide components from the Chinese medicinal material Chrysanthemum chrysanthemum to prepare drugs for enhancing body immunity. Background technique [0002] With the development of society and economy, more and more office workers are affected by factors such as overwork, anxiety, lack of exercise and unbalanced diet, which lead to low immunity of the body. How to find a safe and low-cost immune-boosting natural medicine is the goal that researchers in this field have been working tirelessly to find. [0003] The wild chrysanthemum is the inflorescence head of Chrysanthemum indicum L., C.boreale Mak. or C. lavandulaefolium (Fisch.) Mak. of Compositae. Growing on hillside meadows, shrubs, riverside wetlands, coastal saline lands, fie...

AI Technical Summary

Problems solved by technology

Chrysanthemum indicum polysaccharide (CIP) has the functions of anti-aging and scavenging active oxygen free radicals, but the research on its immunomodulatory effect has not been reported so far