Novel compound donkey-hide glue extract powder formula, preparation and application of novel compound donkey-hide glue extract powder formula
A technology of compound donkey-hide gelatin and extract powder, which is applied to the traditional Chinese medicine prescription of oral or external use. The new compound donkey-hide gelatin traditional Chinese medicine extract and the preparation field thereof can solve the problem of weakening the self-cleaning effect of the vagina, prone to inflammation and iatrogenic infection. and other problems, to achieve the effect of preventing re-bleeding infection, avoiding re-infection, and shortening the course of myogenesis.
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Embodiment 1
[0026] The preparation method of embodiment one compound donkey-hide gelatin extract powder
[0027] According to the difference of yin and yang, qi and blood and according to the severity of damp-heat symptoms, prepare the following different proportions of raw materials:
[0028] Prescription 1: 45 parts of Ejiao, 35 parts of Astragalus, 12 parts of Codonopsis; 24 parts of Salvia, 24 parts of Polyporus, 22 parts of Poria, 25 parts of Radix Paeoniae Rubra, and 3 parts of Puhuang.
[0029] Prescription 2: 30 parts of Ejiao, 0 parts of Astragalus, 35 parts of Codonopsis; 15 parts of Salvia, 6 parts of Polyporus, 18 parts of Poria, 15 parts of Radix Paeoniae Rubra, and 15 parts of Puhuang.
[0030] Prescription 3: 22 parts of donkey-hide gelatin, 22 parts of astragalus, 0 part of Codonopsis pilosula; 18 parts of salvia miltiorrhiza, 16 parts of polyporus, 12 parts of poria cocos, 17 parts of red peony, and 12 parts of Puhuang.
[0031] Prescription 4: 20 parts of donkey-hide ge...
Embodiment 2
[0041] Example 2 Study on the therapeutic effect of new compound donkey-hide gelatin extract powder administered through vaginal route
[0042] (1) Study on the therapeutic effect of new compound donkey-hide gelatin extract powder on acute pelvic inflammatory disease in rats
[0043] 1. Experimental drugs
[0044] 1.1 Name: New compound donkey-hide gelatin extract powder (the name used for the test: jj-0808, prepared from the prescription in Example 1), brown, and the dosage for humans is 1.5-2g / person (calculated according to the extract powder of raw materials).
[0045] 1.2 Positive control drug: Fule Granules, produced by Sichuan Baoguang Pharmaceutical Co., Ltd., 6g x bag, 12g each time, twice a day, take with boiling water. Oral administration (ig), animal dosage 2.4g / kg.
[0046] 1.3 Other drugs
[0047] Ketamine hydrochloride injection, specification: 2ml: 0.18 / ×10 sticks, Jiangsu Hengrui Medicine Co., Ltd.
[0048] Xinwei brand iodophor disinfectant, Jiangsu Xingh...
Embodiment 3
[0146] Example 3 Study on the protective effect of the extract of the present invention on lung injury caused by rabbit oleic acid
[0147] 1. Experimental Drugs
[0148] 1. Luoantai JJ0908 (also called JJ0908 in this practice) (internal use) (extract of the present invention) brown extract containing extract powder 0.47g / mL
[0149] 2. Luoantai JJ0808 (also known as JJ0808 in this implementation) (control) (original technical prescription) brown extract powder
[0150] 3. Oleic acid chemically pure from Shanghai Lingfeng Chemical Reagent Co., Ltd.
[0151] 2. Experimental animals
[0152] New Zealand white rabbits (2.1-2.3kg, half male and half male, 40 rabbits) provided by Nanjing Anlimo Technology Co., Ltd.;
[0153] 3. Animal experiment conditions:
[0154] Experimental site: Animal Laboratory Building, Nanjing Medical University
[0155] Animal laboratory: temperature 20-24 ℃, humidity 40-70%
[0156] 4. Experimental method
[0157] 5.1 Pre-experiment
[0158] 5.1...
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