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Device for treating Parkinson's disease

A technology for Parkinson's disease and a treatment device, applied in the field of Parkinson's disease treatment devices, can solve problems such as affecting the survival of electrode nerve cells, increasing electrode interface impedance, increasing the distance between electrodes and target neurons, etc.

Active Publication Date: 2012-11-28
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Deep brain electrical stimulation has a certain therapeutic effect, but there are also many shortcomings: First, deep brain electrical stimulation lacks selectivity and specificity, and in many cases the mechanism of treatment is not clear. A certain degree of unpredictability, and may even have side effects
Secondly, after long-term implantation of stimulation devices, inflammatory reactions are often caused due to surgical trauma and biocompatibility of implanted materials. With the formation of astrocyte cysts, the impedance of the electrode interface will increase significantly. Large, the stimulating effect is significantly weakened
In addition, cysts will also affect the survival of nerve cells around the electrode, increasing the distance between the electrode and the target neuron, which will seriously affect the therapeutic effect of deep brain stimulation
In addition, deep brain electrical stimulation is difficult to achieve neuron inhibition

Method used

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  • Device for treating Parkinson's disease
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Embodiment Construction

[0020] The Parkinson's disease treatment device will be further described below in conjunction with the accompanying drawings.

[0021] Such as figure 1 As shown, an embodiment of Parkinson's disease treatment device 100 is used to detect and treat nerve tissue 200, which includes a central processing system 110, an electrophysiological signal generation detection system 120, a drug delivery system 130 and a light stimulation system 140 .

[0022] The central processing system 110 comprehensively controls the electrophysiological signal generation and detection system 120 , the drug delivery system 130 and the light stimulation system 140 .

[0023] In this embodiment, the electrophysiological signal generation detection system 120 includes a neurotransmitter sensor 122 for detecting the concentration and change of the neurotransmitter in the target area, and a recording electrode for recording the local field potential and neural electrical activity of nerve tissue cells. 1...

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Abstract

The invention relates to a device for treating Parkinson's disease. The device comprises an electrophysiological signal generation detecting system, a drug delivery system, a photostimulation system, and a central processing system. The central processing system controls the electrophysiological signal generation detecting system, the drug delivery system, and the photostimulation system. The electrophysiological signal generation detecting system comprises a neurotransmitter sensor, a recording electrode, and a stimulating electrode. The drug delivery system comprises a syringe pump and a micro-catheter. The central processing system controls the syringe pump to perform drug slow release through the micro-catheter. The photostimulation system comprises a waveform generator, a light source and optical fibers. The waveform generator controls frequency of laser emitted by the light source. The laser emitted by the light source is transmitted to the optical fibers and is used for photostimulation treatment on imported nervous tissue cells with photaesthesia genes. A device for treating the Parkinson's disease is provided, and the device has relatively good monitoring and treating effects and is relatively safe.

Description

technical field [0001] The invention relates to the field of medical equipment, in particular to a treatment device for Parkinson's disease. Background technique [0002] Parkinson's disease (Parkinson's disease) is a common degenerative disease of the central nervous system in middle-aged and elderly people. It becomes stiff, and in the advanced stage, it will cause the patient to be unable to take care of themselves, which will bring a greater burden to the patient and their family members. In addition, with the gradual aging of the global population, neurological diseases such as Parkinson's disease have increased significantly and gradually become a major social burden. [0003] In recent years, neuromodulation therapy has developed rapidly in the application of neurological diseases such as Parkinson's disease. At present, a variety of neuromodulation therapy methods have been developed, such as repetitive transcranial magnetic stimulation, transcranial direct electric...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/36A61N5/067A61B5/04
Inventor 鲁艺王立平张元元钟成蔚鹏飞刘楠
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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