Iron protein succinylate oral solution and preparation method thereof
A technology of iron protein succinate and oral solution, which is applied in the field of medicine to achieve the effect of good taste, good solubility and simple operation
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Embodiment 1
[0030] A kind of ferric protein succinate oral solution, it is prepared by following method:
[0031] 1) Weigh 45 grams of iron protein succinate, add 600ml of purified water and stir, adjust the pH value to about 6.0 with 4mol / L sodium hydroxide solution, and fully stir to dissolve;
[0032] 2) Weigh 50 grams of sorbitol, 1 gram of sodium methylparaben (sodium methylparaben), 0.1 grams of sodium propylparaben (sodium propylparaben) and 2.5 grams of stevia, and use 100ml Dissolve in water (60°C), add to the above solution after complete dissolution;
[0033] 3) Add 20 grams of propylene glycol and 4.0 grams of orange essence, stir evenly, adjust the pH value to 7.2-7.4 with 4mol / L sodium hydroxide solution, add purified water to make the volume to 1L, stir well, and filter;
[0034] 4) Detect the pH value and iron content. After passing the test, fill it, add a Seza cover, and sterilize at 100°C for 30 minutes;
[0035] 5) Subpackaging in units of 15ml to obtain the iron pro...
Embodiment 2
[0037] A kind of ferric protein succinate oral solution, it is prepared by following method:
[0038] 1) Weigh 65 grams of iron protein succinate, add 600ml of purified water and stir, adjust the pH value to about 6.0 with 4mol / L sodium hydroxide solution, heat to 65°C, and fully stir to dissolve;
[0039] 2) Weigh 120 grams of sorbitol, 10 grams of sodium methylparaben (sodium methylparaben), 3 grams of sodium propylparaben (sodium propylparaben) and 10 grams of stevia, and use 100ml Dissolve in water (60°C), add to the above solution after complete dissolution;
[0040] 3) Add 100 grams of propylene glycol and 10 grams of orange essence, stir evenly, adjust the pH value to 7.2-7.4 with 4mol / L sodium hydroxide solution, add purified water to make the volume to 1L, stir well, and filter;
[0041] 4) Detect the pH value and iron content. After passing the test, fill it, add a Seza cover, and sterilize at 100°C for 30 minutes;
[0042] 5) Subpackaging in units of 15ml to obtai...
Embodiment 3
[0044] A kind of ferric protein succinate oral solution, it is prepared by following method:
[0045] 55.3 grams of iron protein succinate, 93.3 grams of sorbitol, 66.7 grams of propylene glycol, 3.0 grams of sodium methylparaben, 1.0 grams of sodium propylparaben, 2.5 grams of stevia, 4.0 grams of orange flavor, appropriate amount of sodium hydroxide , after dissolving, dilute to 1000 ml with purified water.
[0046] 1) Weigh 55.3 grams of iron protein succinate, add 600ml of purified water and stir, adjust the pH value to about 6.0 with 4mol / L sodium hydroxide solution, and fully stir to dissolve;
[0047] 2) Weigh 93.3 grams of sorbitol, 3.0 grams of sodium methylparaben (sodium methylparaben), 1.0 grams of sodium propylparaben (sodium propylparaben) and 2.5 grams of stevia, and use 100ml Dissolve in water (60°C), add to the above solution after complete dissolution;
[0048]3) Add 66.7 grams of propylene glycol and 4.0 grams of orange essence, stir evenly, adjust the pH ...
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