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Calcium glutamate, and preparation method and application thereof

A technology of calcium glutamate and glutamic acid, which is applied in the fields of application, food preparation, chemical instruments and methods, etc., can solve problems such as general absorption effect, difficult disintegration and absorption of tablets, and high phosphorus content, so as to reduce the cost of calcium supplementation , various indicators are excellent, and the effect of simple operation

Inactive Publication Date: 2013-02-13
SHANGHAI GUANSHENGYUAN TIANCHU FLAVORING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, Calcium Calcium contains 16 mg of calcium per tablet, and if the daily calcium supplement is 1000 mg, 62 tablets are required; each tablet of Vita Calcium is 15.5 mg, and 65 tablets are required; each tablet of various calcium is 28.2 mg, and 34 tablets are required; are not widely available for treatment
[0006] 2. Calcium Ammonium Phosphate: It is a calcium supplement commonly used in Japan. It contains 23.3% calcium, which is relatively high. It is also produced by Chengdu Pharmaceutical Factory in my country. The calcium content of each tablet is 70 mg. The calcium content and drug price are medium, but its The disadvantage is that it is difficult to disintegrate and absorb the tablet, and it is high in phosphorus, which is harmful to people with renal dysfunction, so it is less used
However, due to the average chelating power of citric acid and calcium ions, it will precipitate when it enters the human body, so the absorption effect of the human body is average.
[0008] 4. Active calcium: it is a calcium mixture formed by calcining biological calcium (shellfish) at high temperature. It has high calcium content, but its aqueous solution is strongly alkaline and irritating to the gastrointestinal tract. It is not suitable for elderly people with achlorhydria

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The preparation of embodiment 1 calcium glutamate

[0033] In the aqueous solution of pH 6.0, 1:0.477 glutamic acid and calcium hydroxide were reacted, the reaction temperature was 89° C., and the reaction time was 32 minutes. Yield 98%, purity 99%.

[0034] The obtained calcium glutamate content is 11%, and the index meets the Q / YQSQ210 standard.

Embodiment 2

[0035] The preparation of embodiment 2 calcium glutamate

[0036] In the aqueous solution with pH 5.5, react 1:0.5 glutamic acid and calcium hydroxide, the reaction temperature is 89° C., and the reaction time is 32 minutes. Yield 98%, purity 99%.

[0037] The obtained calcium glutamate content is 11%, and the index meets the Q / YQSQ210 standard.

Embodiment 3

[0038] The preparation of embodiment 3 calcium glutamate

[0039] In the aqueous solution of pH 6.5, react 1:0.3 glutamic acid and calcium hydroxide, the reaction temperature is 89° C., and the reaction time is 32 minutes. Yield 98%, purity 99%.

[0040] The obtained calcium glutamate content is 11%, and the index meets the Q / YQSQ210 standard.

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PUM

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Abstract

The invention discloses a preparation method of calcium glutamate. The preparation method comprises a step that calcium glutamate can be obtained through reacting glutamic acid with calcium hydrate preferably in an aqueous solution having a pH value of 6.0 at 89DEG C for 32min according to a ratio of glutamic acid to calcium hydrate of 1:0.477. The invention also discloses calcium glutamate prepared through the preparation method, and an application of calcium glutamate in the preparation of monosodium glutamate. The content of calcium in calcium glutamate is 11%, the calcium glutamate has a good water solubility and a high human body absorption rate, the chelating ability of glutamic acid to calcium ions is 146.3, and the delicate flavor of the monosodium glutamate obtained through applying the calcium glutamate can reach about 80% of the delicate flavor of common monosodium glutamate, and the monosodium glutamate obtained through applying the calcium glutamate can completely replace the common monosodium glutamate, is a functional delicate flavor adjusting substance integrating calcium supplement with delicate flavor adjustment, can simultaneously replace the common monosodium glutamate and various calcium supplents, accords with a healthy diet concept, and also can reduce the calcium supplement costs of consumers.

Description

technical field [0001] The present invention relates to a kind of calcium glutamate and its preparation method and application. Background technique [0002] Calcium is an inorganic element with the most content in the human body. When a person is born, the calcium content in the body is 20-25 grams, and it reaches 1000-1200 grams in adulthood, accounting for 2% of the body weight. Calcium has three physiological functions: one is to form various bones and teeth that support the body; the other is to maintain the normal activities of nerves and muscles; the third is to promote the activity of various enzymes in the body and participate in the physiological process of blood coagulation. Therefore, calcium is a very important inorganic element with the highest content in the human body. The lack of this important inorganic element will inevitably cause a series of diseases, such as rickets in children, osteomalacia in adults, osteoporosis in middle-aged and elderly people, et...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07C229/24C07C227/18A23L1/228A23L27/22
Inventor 吴坚
Owner SHANGHAI GUANSHENGYUAN TIANCHU FLAVORING
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