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Clean L-arginine production technology

An arginine and process technology, applied in the field of L-arginine clean production technology, can solve the problems of low L-arginine recovery rate, complex extraction process, waste liquid efflux and the like, so as to increase economic benefits and avoid A large amount of waste water and the effect of reuse

Active Publication Date: 2013-06-12
SHANDONG FUFENG FERMENTATION CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent 2010105207645 discloses a method for extracting L-arginine from fermentation broth. The extraction process of this method is complicated, the recovery rate of L-arginine is low, and a large amount of waste liquid is discharged, polluting the environment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A kind of L-arginine clean production technique, it comprises the steps:

[0023] (1) 150L of L-arginine fermentation broth was sterilized by microfiltration membrane filtration, and the retentate and filtrate were collected respectively; Combine with the concentrated solution and dry to obtain 10.3Kg of animal nutrition feed; the above-mentioned purified solution is concentrated 5-10 times and then slowly cooled to 20°C, and the isoelectric solution with a pH of 9.5-10.5 is slowly adjusted with ammonia water (or ammonia gas); The microfiltration membrane is an inorganic ceramic membrane with a molecular weight cut-off of 20,000 MW, a pore size of 2 μm, and a microfiltration temperature of 50-60°C; the ultrafiltration membrane is one of PE, PAN, PP, PES, PC or PVDF, with a molecular weight cut-off 1000MW, the pore size is 50nm;

[0024] (2) Settling the isoelectric solution of step (1) for 6-10 hours, centrifuging, collecting the precipitate 1 and the supernatant 1, st...

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PUM

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Abstract

The invention belongs to the technical field of amino acid production and discloses a clean L-arginine production technology. According to the clean L-arginine production technology, the influence of bacterial proteins on downstream extraction is eliminated by adopting multiple filter membranes for removing bacteria in an L-arginine fermentation liquid extracting process, and an L-arginine product is obtained through low-temperature equal-point extraction, wherein a bacterial protein concentrated solution is used for producing a protein feed, and last mother liquid is used for producing a feremented ammonium sulfate compound fertilizer. The clean L-arginine production technology can avoid the problem of difficulty in waste liquid treatment in the fermentation liquid extraction process, is simple and convenient in industrialization, has strong controllability and considerable economic benefits, is environmentally-friendly in the production process and is a clean arginine large-scale production technical route.

Description

technical field [0001] The invention belongs to the technical field of amino acid production, and relates to a clean production process of L-arginine. Background technique [0002] Arginine (arginine, Arg) chemical name: 2-amino-5-guanidino-pentanoic acid, is an aliphatic basic polar α-amino acid containing guanidinium group, which is positively charged under physiological conditions; L -Arginine is the encoded amino acid in protein synthesis. For mammals, arginine is classified as a semi-essential or conditionally essential amino acid, depending on the developmental stage and health status of the organism. Natural products exist in large quantities in protamine and are also the basic components of various proteins. [0003] L-arginine is hailed as a "magic molecule" by scientists. It is one of the basic amino acids. For healthy adults, it is a non-essential amino acid, but arginine is an essential amino acid for maintaining the growth and development of infants; It is an ...

Claims

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Application Information

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IPC IPC(8): C07C279/14C07C277/08C05G1/00A23K1/16
Inventor 李德衡严纪文李树标刘元涛刘建阳李玉成王玉杰
Owner SHANDONG FUFENG FERMENTATION CO LTD