Hemocyte analysis chip and system for using chip thereof

A blood cell analysis and blood cell technology, which is applied in the field of blood cell analysis chips, can solve the problems of large volume of blood cell analyzers, time-consuming and laborious maintenance, and difficulty in popularization, and achieves the effects of fast analysis speed, convenient operation and simple structure.

Active Publication Date: 2013-06-26
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI +1
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Problems solved by technology

This type of blood cell analyzer is bulky, expensive, time-consuming and laborious to repair, and can only analyze one sample at a time. At the s

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  • Hemocyte analysis chip and system for using chip thereof
  • Hemocyte analysis chip and system for using chip thereof
  • Hemocyte analysis chip and system for using chip thereof

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Embodiment Construction

[0026] In order to further explain the technical means and effects of the present invention to achieve the intended purpose of the invention, the specific implementation, structure, Features and their functions are described in detail below.

[0027] figure 1 Shown is a schematic diagram of the blood cell analysis system of the present invention. Such as figure 1 As shown, the blood cell analysis system 100 is a blood cell analysis system based on a microfluidic analysis platform, which includes a blood cell analysis chip 10 , an electrical impedance detection unit 20 , a signal processing system 30 and a display 40 .

[0028] Among them, the blood cell analysis chip 10 is made of quartz, glass, single crystal silicon, polymer materials such as polymethylmethacrylate (PolymethylMethacrylate, PMMA), polydimethylsiloxane (polydimethylsiloxane, PDMS), polycarbonate (Polycarbonate) , PC) etc., on which there are detection channels E1, K1 with detection holes F, M (such as figur...

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Abstract

The invention provides a hemocyte analysis chip and an analysis system. The system comprises the chip, an electrical impedance detection unit and a signal processing system. The chip comprises a first detection chip and a second detection chip. The first detection chip comprises a blood sample channel, an erythrocyte lysate channel, a continuous phase channel and a first detection channel. The second detection chip comprises the blood sample channel, the continuous phase channel and a second detection channel. The blood sample channel, the erythrocyte lysate channel and the continuous phase channel of the first detection chip are communicated, and a communication position is connected with the first detection channel, the blood sample channel of the second detection chip is communicated with the continuous phase channel, and the communication position is connected with second detection channel, a small disperse aperture is provided between the connection positions of first detection channel and the second detection channel and the fluid passage, and a small detection aperture is provided at the position far from the small disperse aperture. The electrical impedance detection unit and the signal processing system use an electrical impedance method for analyzing hemocyte.

Description

technical field [0001] The invention relates to a blood cell analysis chip based on microfluidic droplet technology and a system using the chip. Background technique [0002] Blood flows through various tissues and organs of the human body, and the interaction and mutual influence between various tissues and organs of the human body is realized through the regulation and balance of nerves and body fluids. This balance is reflected in various physical parameters of blood, physiological parameters etc. The information obtained by hematological tests can help diagnose and differentially diagnose diseases related to the blood system, analyze the condition, observe the curative effect, and judge the prognosis, provide evidence for disease prevention, guide clinical medication and carry out clinical medical research. Blood cytology analysis is not only the main basis for diagnosing various diseases of the hematopoietic system, but also provides important information for the diagn...

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Application Information

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IPC IPC(8): G01N33/50G01N15/10G01N27/02
Inventor 李芳芳游璠周树民黄石樊建平
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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