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Radiation-proof skin-care gel and preparation method thereof

A skin care gel and radiation protection technology, applied in the field of medicine, can solve the problems of hypoxia secondary cells, pigmentation, skin erythema, etc., and achieve the effect of improving local blood circulation, promoting tissue repair, and reducing radiation damage

Inactive Publication Date: 2013-08-21
SHANXI TUMOUR INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, radiotherapy will cause different degrees of skin damage, leading to the interruption of the course of radiotherapy. After radiotherapy, the patient's skin will appear erythema due to telangiectasia, and then pigmentation, microthrombosis in small blood vessels, resulting in local hypoxia and secondary cell damage. Peeling, ulceration, bleeding, necrosis, etc.
If grade III and above skin reactions occur, radiotherapy needs to be suspended, which will delay the treatment time, affect the curative effect, and increase the pain of the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] formula

[0038] 10 grams of American ginseng, 80 grams of Angelica dahurica, 20 grams of woody fragrance, 10 grams of Sophora japonica, 10 grams of Scutellaria baicalensis, 5 grams of Evodia rutaecarpa, 80 grams of glycerin, and 8 grams of carbomer.

[0039] Preparation

[0040] Mix American ginseng, Angelica dahurica, Woody Fragrance, Sophora japonica, Scutellaria baicalensis and Evodia rutaecarpa according to the above formula ratio, and then crush them into coarse particles, add 75% ethanol with 5 times the mass of the above five main ingredients, seal it, soak it at room temperature for 6 days, and take out the supernatant; Add 3 times the mass of 75% ethanol to the residue, soak at room temperature for 6 days and take out the supernatant; combine the two extracts, filter, add glycerin and stir well, adjust the liquid volume to 1000ml with 75% ethanol, add Dissolve Carbomer 940, homogenize it in a homogenizer, and fill it into a vial.

Embodiment 2

[0042] formula

[0043] 20 grams of American ginseng, 90 grams of Angelica dahurica, 40 grams of woody fragrance, 20 grams of Sophora japonica, 20 grams of Scutellaria baicalensis, 10 grams of Evodia rutaecarpa, 120 grams of glycerin, and 12 grams of carbomer.

[0044] Preparation

[0045]Mix American ginseng, Angelica dahurica, Woody Fragrance, Sophora japonica, Scutellaria baicalensis and Evodia rutaecarpa according to the ratio of the above formula and grind them into coarse particles, add 75% ethanol which is 7 times the mass of the above five main ingredients, seal it, soak it at room temperature for 8 days, and take out the supernatant; Add 5 times the mass of 75% ethanol to the residue, take out the supernatant after soaking at room temperature for 8 days; combine the two extracts, filter, add glycerin and stir well, adjust the liquid volume to 1000ml with 75% ethanol, and add Dissolve Carbomer 940, homogenize it in a homogenizer, and fill it into a vial.

Embodiment 3

[0047] formula

[0048] 15 grams of American ginseng, 85 grams of Angelica dahurica, 30 grams of woody fragrance, 15 grams of Sophora japonica, 15 grams of Scutellaria baicalensis, 8 grams of Evodia rutaecarpa, 100 grams of glycerin, and 10 grams of carbomer.

[0049] Preparation

[0050] Mix American ginseng, Angelica dahurica, Woody Fragrance, Sophora japonica, Scutellaria baicalensis and Evodia rutaecarpa according to the above-mentioned formula ratio, and then crush them into coarse particles, add 75% ethanol with 6 times the mass of the above-mentioned five main ingredients, seal it, soak it at room temperature for 7 days, and take out the supernatant; Add 4 times the mass of 75% ethanol to the residue, take out the supernatant after soaking at room temperature for 7 days; combine the two extracts, filter, add glycerin and stir well, adjust the liquid volume to 1000ml with 75% ethanol, add Dissolve Carbomer 940, homogenize it in a homogenizer, and fill it into a vial.

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PUM

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Abstract

The invention provides radiation-proof skin-care gel. The gel can be used for preventing and treating a radiation skin injury, and comprises the following crude medicines in parts by weight: 10-20 parts of American ginseng, 80-90 parts of radix angelicae, 20-40 parts of elecampane, 10-20 parts of sophora flower, 10-20 parts of scutellaria baicalensis, and 5-10 parts of fructus evodiae; and 80-120 parts of glycerol as a substrate material and 8-12 parts of Carbomer are added when the main crude medicines are prepared into gels. The skin-care gel disclosed by the invention can promote local tissue metabolism, plays a role of protecting the skin, prevents or reduces an injury caused by radiation on the skin tissue, and is good in curative effective, convenient to use and low in medicine cost.

Description

[0001] technical field [0002] The invention relates to a medicine, in particular to an external gel for preventing and treating radiation skin damage during radiation therapy. Background technique [0003] Radiation therapy is an important treatment for patients with malignant tumors. However, radiotherapy will cause different degrees of skin damage, leading to the interruption of the course of radiotherapy. After radiotherapy, the patient's skin will appear erythema due to telangiectasia, and then pigmentation, microthrombosis in small blood vessels, resulting in local hypoxia and secondary cell damage. Desquamation, ulceration, hemorrhage, necrosis, etc. If skin reactions of grade III and above occur, radiotherapy needs to be suspended, thereby delaying the treatment time, affecting the curative effect, and increasing the pain of the patient. Contents of the invention [0004] The object of the present invention is to provide a kind of anti-radiation skin care gel, w...

Claims

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Application Information

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IPC IPC(8): A61K36/754A61K9/06A61P17/16
Inventor 王国平任连生杨喜花张蘋
Owner SHANXI TUMOUR INST
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