Preparation method of bone repair bracket with osteoid poriform regeneration channel structure
A channel structure, osteoid technology, applied in medical science, prosthesis, etc., can solve the problems of new tissue necrosis, poor permeability, cell apoptosis, etc., to promote bone tissue regeneration and repair, improve mechanical properties, and meet popularization and application. Effect
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[0025] Example 1
[0026] According to the literature (Li JD, Zuo Y, Cheng XM, Yang WH, Wang HN, Li YB, Preparation and characterization of nano-hydroxyapatite / polyamide 66 composite GBR membrane with asymmetric porous structure, Journal of Material Science-materials in medicine, 2009, Vol. 30, No. 5: 1031-1038) reported the preparation of nano-apatite (n-HA)-polyamide 66 (PA66) composite slurry. Heat and evaporate the ethanol solvent, so that the n-HA-PA66 composite slurry can reach the proper viscosity. The composite slurry was evenly coated on a 304 stainless steel wire with a diameter of 300 μm, and then 40 stainless steel wires coated with the slurry were tied into a bundle and placed in a PE heat shrinkable tube, and one end of the heat shrinkable tube was sealed. Heat the heat shrink tube to 90°C and keep it for 0.5 hours to make the heat shrink tube start to shrink. Increase the temperature and continue heating to 95°C and keep it for 4 hours. After the material is co...
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[0027] Example 2
[0028] Prepare nano-apatite-polyamide 66 (n-HA-PA66) composite material according to the method reported in CN1544099, and then use methanol as solvent to prepare n-HA-PA66 composite slurry with suitable viscosity. The composite slurry was evenly coated on 304 stainless steel wires with a diameter of 150 μm, and then 50 stainless steel wires coated with the slurry were tied into a bundle and placed in a PET heat shrinkable tube, and one end of the heat shrinkable tube was sealed. Heat the heat shrink tube to 80°C and keep it for 1 hour to make the heat shrink tube start to shrink. Increase the temperature and continue heating to 100°C and keep it for 6 hours. After the material is completely cured, remove the heat shrinkable tube, soak it in deionized water for 3 hours, and pull out the stainless steel wire after the material swells. Then, the material was ultrasonically cleaned 5 times in deionized water, 5 minutes each time, and dried to obtain a bone repa...
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[0030] Example 3
[0031] According to the method of the literature described in Example 1, the nano-apatite-polyamide 66 (n-HA-PA66) composite slurry was prepared with propanol as the solvent. By heating and evaporating the solvent propanol, the n-HA-PA66 composite slurry can reach the proper viscosity. The composite slurry is uniformly coated on 304 stainless steel wire with a diameter of 500 μm, and then 40 stainless steel wires coated with the slurry are tied into a bundle and placed in a PE heat shrinkable tube, and one end of the heat shrinkable tube is sealed. Heat the heat shrink tube to 110°C and keep it for 2 hours so that the heat shrink tube starts to shrink. Increase the temperature and continue heating to 150°C and keep it for 3 hours. After the material is completely cured, remove the heat shrinkable tube, soak it in deionized water for 3 hours, and pull out the stainless steel wire after the material swells. Then the material was ultrasonically cleaned 5 times...
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