A kind of preparation method of perfluoroalkane

Abstract

The invention provides a method for preparing perfluoroalkane. The method comprises the following steps of: filling a filler in a reactor, fluorating by using a fluorating agent, keeping the temperature inside the reactor between 100 to 300 DEG C, adding reaction materials in a vaporizer to vaporize, controlling the temperature inside the vaporizer between 130 to 150 DEG C, wherein the reaction materials comprise C5-C16 alkanes and one or more of partial fluorides of the C5-C16 alkanes, continuously bringing reaction material vapor in the reactor by using an inert gas, continuously feeding the fluorating agent in the reactor to react with the reaction material vapor continuously fed in the reactor, and separating and purifying to obtain the perfluoroalkane. The method provided by the invention is suitable for large-scale continuous productions; the reaction conditions are easily controlled; the yield is high; the by-products are less; the reaction production is easily separated and purified; no three wastes are discharged during the production process. With the adoption of the method, perfluorooctane with the purity being greater than or equal to 98% can be prepared and can act as a production material of lung cavity ventilation aerating liquid and a preparation for ophthalmologic operations.

Description

technical field [0001] The invention relates to a preparation method of perfluoroalkane, in particular to a lung cavity ventilation liquid and a preparation method thereof. Background technique [0002] In the past, the preparation methods of perfluorooctane include cobalt trifluoride fluorination method and electrolytic fluorination method. The cobalt trifluoride method needs to convert cobalt difluoride into cobalt trifluoride by fluorination first, and then cobalt trifluoride reacts with octane in the reactor to obtain a mixture containing perfluorooctane; cobalt trifluoride needs to be continuously regenerated , the temperature of the reactor is difficult to control uniformly, the scale-up is limited, the production cannot be carried out continuously, and it is not suitable for mass production. In addition, the electrolytic fluorination method to synthesize perfluorooctane has complex equipment, difficult condition control, many by-products, and low yield, which general...

AI Technical Summary

Problems solved by technology

The cobalt trifluoride method needs to convert cobalt difluoride into cobalt trifluoride by fluorination first, and then cobalt trifluoride reacts with octane in the reactor to obtain a mixture containing perfluorooctane; cobalt trifluoride needs to be continuously regenerated , the reactor temperature is difficult to control uniformly, the scale-up is limited, the production cannot be carried out continuously, and it is not suitable for mass production

In addition, the electrolytic fluorination method to synthesize perfluorooctane has complex equipment, difficult condition control, many by-products, and low yield, which generally does not exceed 15%.