Solid granular foreign matter detection device and method for automatic light examining machine

Abstract

The invention relates to a solid granular foreign matter detection device and method for an automatic light examining machine. The solid granular foreign matter detection device comprises a radiation source system, a forward receiving Fourier lens, a forward photodetector array and a signal processing system which are arranged in sequence, and the radiation source system comprises a laser transmitter, a collimating and beam expanding lens, a spatial filter and a backward sending Fourier lens which are arranged in sequence. A divergent laser beam is provided by the radiation source system and forms parallel monochromatic lasers after being subjected to collimation and beam expanding, and a clean liquid medium which contains solid fine granular foreign matter is put in a transparent container which is positioned in front of the forward receiving Fourier lens. Before the detection, the liquid medium and the solid granular foreign matter are uniformly mixed and rotated at high speed, and when the parallel monochromatic lasers irradiate the solid granular foreign matter, the Fraunhofer diffraction phenomenon occurs. Scattered light which is gathered by the photodetector array is converted to a voltage signal which contains information about the solid granular foreign matter, and the solid granular foreign matter is detected by the signal processing system according to the change of the voltage signal.

Description

technical field [0001] The invention relates to a detection device for solid particle foreign matter in a clean liquid medium, especially a detection technology for insoluble solid particle foreign matter mixed in injection injections and infusions in the pharmaceutical industry. Particle foreign matter detection device and method thereof. Background technique [0002] In the manufacturing process of the pharmaceutical industry, the automatic light inspection machine is a special inspection equipment that uses optical imaging and computer to match the obtained images to automatically detect the packaged medical liquid preparations. The computer analyzes and processes the collected image data, detects and judges medical liquid preparations, and rejects unqualified products. [0003] like figure 1 As shown, at present, the existing light inspection machines in China use the LED light source 10 to irradiate the water injection container 6 from the back or the bottom surface, ...

AI Technical Summary

Problems solved by technology

[0004] Due to the software and hardware technical bottlenecks of the existing image processing technology and the inconsistent thickness of the water injection bottles made in China, most of the domestic and even foreign light inspection machines have technical problems of low detection repeatability when used in China, and currently, using The lower limit of detection of solid particles by the image method is about 20 microns, while the Chinese Pharmacopoeia stipulates that there are less than 20 particles larger than 10 microns and less than 3 solid particles larger than 25 microns per milliliter of infusion

Therefore, in the current state of technology, it is difficult to use the image method to detect solid particle foreign matter less than 20 microns, and it is difficult to guarantee the repeatability of the detection results.

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