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Thiamine preparation for preventing and treating rumen acid chronic acidosis

A technology of thiamine and acidosis, applied in applications, animal feed, animal feed, etc., can solve problems such as rumen acidosis, volatile fatty acid ratio imbalance, lactic acid accumulation, etc., to prevent chronic acidosis, reduce accumulation, improve The effect of fermentation

Inactive Publication Date: 2013-09-18
YANGZHOU UNIV
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  • Abstract
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Problems solved by technology

However, it was found in production that ruminants also need to add water-soluble vitamins such as thiamine to their diets under special physiological conditions such as high-concentrate feeding conditions or lactation and pregnancy. Once the body lacks thiamine, the The obstruction of carbohydrate metabolism will lead to the accumulation of intermediate metabolites lactic acid and the imbalance of volatile fatty acid ratio, which will induce ruminal acidosis

Method used

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  • Thiamine preparation for preventing and treating rumen acid chronic acidosis
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  • Thiamine preparation for preventing and treating rumen acid chronic acidosis

Examples

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Effect test

Embodiment 1

[0020] Embodiment 1: The influence of thiamine hydrochloride compound preparation on rumen fermentation of dairy cows

[0021] In this study, an in vivo test method was used. Three 4-year-old Holstein cows with a body weight of (650±20) kg, an average milk yield of (16.5±0.5) kg, and a ruminal cannula were selected and fed with conventional diets (the ratio of fine to coarse: 40:60 , control group), the diet of the high-concentrate group (concentrate-to-coarse ratio was 70:30), and the diet of the high-concentrate group was supplemented with thiamine compound preparation (concentrate-to-coarse ratio was 70:30, and the amount of thiamine added was 180 mg / kg·DM), a 3×3 Latin square experiment was carried out for each period of 30 days, and the dairy cows fed the high-concentrate diet group all reached SARA in each period. Book

[0022] The effect of thiamine on rumen microbial fermentation of Holstein dairy cows under the condition of high-concentrate diet showed that adding ...

Embodiment 2

[0046] Example 2: Effects of thiamine hydrochloride on growth performance of Holstein cattle

[0047] From July 22, 2012 to September 6, 2012, 60 healthy, 11±1-month-old, and similarly weighted black-and-white cattle in the growing period were selected at Su Niu Farm in Xuzhou City, Jiangsu Province, and divided into 3 groups (Table 6 ), 20 cows in each group, and the test cows were reared in a single pen. The normal diet (concentrate-to-grain ratio was 40:60, control group), the high-concentrate group diet (concentrate-to-coarse ratio was 70:30) and the high-concentrate group diet supplemented with thiamine (concentrate-to-coarse ratio was 70:30, the dosage of thiamine was 180mg / kg·DM), the pre-feeding period of the test was 14 days, and the main test period was 31 days.

[0048] The results of the growth test are shown in Table 2. The growth performance of the high-concentrate and high-concentrate-added thiamine groups was better than that of the conventional diet group, a...

Embodiment 3

[0053] Embodiment 3: the influence of thiamine hydrochloride on the development of dairy cow rumen tissue

[0054] In this experiment, nine 3-month-old calves with a body weight of about 95 kg and similar size were selected and randomly divided into 3 groups, one group was fed a 40:60 conventional diet, and the other group was gradually fed a high-concentrate diet. The other group added 120 mg / kg thiamine hydrochloride during the feeding process of SARA induction until SARA occurred, and the test period was 45 days. After the end of the experimental period, the animals were slaughtered, and the rumen epithelial tissue was collected immediately for electron microscope analysis.

[0055] See the test results Figure 5 . Depend on Figure 5 It can be seen that the ruminal epithelial teats of calves in the conventional diet group and SARA added thiamine group were well developed, showing characteristics such as softness and tongue shape (Fig. 1, 2). Soft (Fig8, Fig9); while th...

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Abstract

The invention relates to a thiamine preparation for preventing and treating rumen acid chronic acidosis, and a use method of the thiamine preparation, for preventing and treating ruminant rumen acid chronic acidosis. The preparation comprises the following ingredients: 180mg of thiamine, 8g of fumaric acid, 0.5g of sodium bicarbonate, 0.03g of nicotinic acid and 0.17g of magnesium oxide. By utilizing the thiamine preparation, by prompting normal conduction of carbohydrate metabolism, the accumulation of lactic acid and VFA (Volatile Fatty Acid) is reduced, and the rumen flora balance is adjusted so as to increase the rumen pH value and improve ruminant rumen fermentation, so that the functions of preventing and treating rumen acidosis, improving ruminant rumen health and improving ruminant production capacity are achieved.

Description

technical field [0001] The invention relates to the preparation of a thiamine preparation for preventing and treating subacute acidosis of rumen acid and its use method, which are used for preventing and treating chronic acidosis of rumen of rumen animals. Background technique [0002] With the gradual development of animal husbandry towards intensive and efficient production, in the production of modern dairy cows, beef cattle and mutton sheep, a large amount of high-concentrate feed with starch as the main energy source is fed in order to improve production efficiency. It also leads to an increase in the incidence of metabolic diseases mainly chronic rumen chronic acidosis (Subacute Ruminal Acidosis, SARA). In developed countries such as Europe and the United States, chronic rumen acidosis has become the main nutritional and metabolic disease concerned by dairy and beef cattle farms. The dairy industry in North America loses 500-1000 million US dollars due to rumen acidosi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K1/175A23K1/18
Inventor 王洪荣王梦芝喻礼怀潘晓花王龙董淑红张红伟蔡晶晶
Owner YANGZHOU UNIV
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